Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation

The crystal structure of caspase-6, a selective effector of axonal degeneration

(2009) Renato Baumgartner et al.   BIOCHEMICAL JOURNAL

Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation

(2009) J. Michael Elliott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Small-Molecule Activators of a Proenzyme

(2009) D. W. Wolan et al.   SCIENCE

Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells

(2008) Guy Klaiman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Large-scale preparation of active caspase-3 in E. coli by designing its thrombin-activatable precursors

(2008) Hyo Kang et al.   BMC BIOTECHNOLOGY

Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease

(2008) Guy Klaiman et al.   MOLECULAR & CELLULAR PROTEOMICS