mRNA 3′end processing: A tale of the tail reaches the clinic

Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222

(2013) V Enciso-Mora et al.   BRITISH JOURNAL OF CANCER

Widespread and extensive lengthening of 3' UTRs in the mammalian brain

(2013) P. Miura et al.   GENOME RESEARCH

Alternative cleavage and polyadenylation: extent, regulation and function

(2013) Ran Elkon et al.   NATURE REVIEWS GENETICS

Alternative cleavage and polyadenylation: the long and short of it

(2013) Bin Tian et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

(2012) Michael G. Berg et al.   CELL

Decreased efficiency of MSH6 mRNA polyadenylation linked to a 20-base-pair duplication in Lynch syndrome families

(2012) Adrien Decorsière et al.   CELL CYCLE

Alternative Polyadenylation Mediates MicroRNA Regulation of Muscle Stem Cell Function

(2012) Stéphane C. Boutet et al.   Cell Stem Cell

Alternative Cleavage and Polyadenylation during Colorectal Cancer Development

(2012) A. R. Morris et al.   CLINICAL CANCER RESEARCH

Fragile X Syndrome

(2012) Yingratana McLennan et al.   CURRENT GENOMICS

A Complex Containing the CPSF73 Endonuclease and Other Polyadenylation Factors Associates with U7 snRNP and Is Recruited to Histone Pre-mRNA for 3'-End Processing

(2012) X.-C. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

PARP1 Represses PAP and Inhibits Polyadenylation during Heat Shock

(2012) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

(2012) Mainul Hoque et al.   NATURE METHODS

Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

(2012) Eleonora de Klerk et al.   NUCLEIC ACIDS RESEARCH

An in-depth map of polyadenylation sites in cancer

(2012) Yuefeng Lin et al.   NUCLEIC ACIDS RESEARCH

The τCstF-64 Polyadenylation Protein Controls Genome Expression in Testis

(2012) Wencheng Li et al.   PLoS One

Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory

(2012) C. A. Hartley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation

(2012) C. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cleavage factor Imis a key regulator of 3′ UTR length

(2012) Andreas R. Gruber et al.   RNA Biology

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

(2012) Eva Matoulkova et al.   RNA Biology

Inhibition of polyadenylation reduces inflammatory gene induction

(2012) A. Kondrashov et al.   RNA

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

(2012) Georges Martin et al.   Cell Reports

Genetics and Regulatory Impact of Alternative Polyadenylation in Human B-Lymphoblastoid Cells

(2012) Oh Kyu Yoon et al.   PLoS Genetics

E2F mediates enhanced alternative polyadenylation in proliferation

(2012) Ran Elkon et al.   GENOME BIOLOGY

Ending the message: poly(A) signals then and now

(2011) N. J. Proudfoot   GENES & DEVELOPMENT

Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing

(2011) Y. Fu et al.   GENOME RESEARCH

Coordinated Post-transcriptional Regulation of Hsp70.3 Gene Expression by MicroRNA and Alternative Polyadenylation

(2011) Michael Tranter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spermatogenetic but not immunological defects in mice lacking the τCstF-64 polyadenylation protein

(2011) Kathy Jo Hockert et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

p38 MAPK Controls Prothrombin Expression by Regulated RNA 3′ End Processing

(2011) Sven Danckwardt et al.   MOLECULAR CELL

Transcriptional Activators Enhance Polyadenylation of mRNA Precursors

(2011) Takashi Nagaike et al.   MOLECULAR CELL

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

Differential usage of transcriptional start sites and polyadenylation sites in FMR1 premutation alleles

(2011) F. Tassone et al.   NUCLEIC ACIDS RESEARCH

CKI isoforms α and ε regulate Star–PAP target messages by controlling Star–PAP poly(A) polymerase activity and phosphoinositide stimulation

(2011) Rakesh S. Laishram et al.   NUCLEIC ACIDS RESEARCH

p53 inhibits mRNA 3′ processing through its interaction with the CstF/BARD1 complex

(2011) F I Nazeer et al.   ONCOGENE

Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

(2011) P. J. Shepard et al.   RNA

Signals for pre-mRNA cleavage and polyadenylation

(2011) Bin Tian et al.   Wiley Interdisciplinary Reviews-RNA

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

(2010) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

α-thalassaemia

(2010) Cornelis L Harteveld et al.   Orphanet Journal of Rare Diseases

An up-close look at the pre-mRNA 3’-end processing complex

(2010) Yongsheng Shi et al.   RNA Biology

Immunoglobulin heavy chain gene regulation through polyadenylation and splicing competition

(2010) Martha L. Peterson   Wiley Interdisciplinary Reviews-RNA

3′ processing of eukaryotic precursor tRNAs

(2010) Richard J. Maraia et al.   Wiley Interdisciplinary Reviews-RNA

Association of a Polyadenylation Polymorphism in the Serotonin Transporter and Panic Disorder

(2009) Sandeep Gyawali et al.   BIOLOGICAL PSYCHIATRY

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex

(2009) Yongsheng Shi et al.   MOLECULAR CELL

Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing

(2009) Kathleen Martincic et al.   NATURE IMMUNOLOGY

A physical and functional link between splicing factors promotes pre-mRNA 3′ end processing

(2009) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

3′ end mRNA processing: molecular mechanisms and implications for health and disease

(2008) Sven Danckwardt et al.   EMBO JOURNAL

CKIα Is Associated with and Phosphorylates Star-PAP and Is Also Required for Expression of Select Star-PAP Target Messenger RNAs

(2008) Michael L. Gonzales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs

(2008) David L. Mellman et al.   NATURE

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE