Gating modes of calcium-activated chloride channels TMEM16A and TMEM16B

Study of permeation and blocker binding in TMEM16A calcium-activated chloride channels

(2015) JP Reyes et al.   Channels

The role of Ca2+ activated Cl− channels in blood pressure control

(2015) Vladimir V Matchkov et al.   CURRENT OPINION IN PHARMACOLOGY

A fluid secretion pathway unmasked by acinar-specificTmem16Agene ablation in the adult mouse salivary gland

(2015) Marcelo A. Catalán et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels

(2015) Christian J. Peters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a lipid scrambling domain in ANO6/TMEM16F

(2015) Kuai Yu et al.   eLife

Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

(2014) Anke Bill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions between permeation and gating in the TMEM16B/anoctamin2 calcium-activated chloride channel

(2014) Giulia Betto et al.   JOURNAL OF GENERAL PHYSIOLOGY

X-ray structure of a calcium-activated TMEM16 lipid scramblase

(2014) Janine D. Brunner et al.   NATURE

The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

(2014) Steven D. Broadbent et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Acidic Amino Acids in the First Intracellular Loop Contribute to Voltage- and Calcium- Dependent Gating of Anoctamin1/TMEM16A

(2014) Qinghuan Xiao et al.   PLoS One

Inhibition of TMEM16A Expression Suppresses Growth and Invasion in Human Colorectal Cancer Cells

(2014) Yujie Sui et al.   PLoS One

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity

(2014) Jason Tien et al.   eLife

The Ca2+-activated Cl−channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis

(2014) Zhiqiang Qu et al.   Cancer Medicine

TMEM16A–TMEM16B chimaeras to investigate the structure–function relationship of calcium-activated chloride channels

(2013) Paolo Scudieri et al.   BIOCHEMICAL JOURNAL

Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels

(2013) Kerstin Vocke et al.   JOURNAL OF GENERAL PHYSIOLOGY

Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes

(2013) Aiste Adomaviciene et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anion permeation in calcium-activated chloride channels formed by TMEM16A from Xenopus tropicalis

(2013) J. P. Reyes et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

(2012) U. Duvvuri et al.   CANCER RESEARCH

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology

(2012) Kuai Yu et al.   CIRCULATION RESEARCH

The voltage dependence of the TMEM16B/anoctamin2 calcium-activated chloride channel is modified by mutations in the first putative intracellular loop

(2012) Valentina Cenedese et al.   JOURNAL OF GENERAL PHYSIOLOGY

Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop

(2011) Q. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tmem16AEncodes the Ca2+-activated Cl−Channel in Mouse Submandibular Salivary Gland Acinar Cells

(2010) Victor G. Romanenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TMEM16A(a)/anoctamin-1 Shares a Homodimeric Architecture with CLC Chloride Channels

(2010) Ghada Fallah et al.   MOLECULAR & CELLULAR PROTEOMICS

Control of volume-sensitive chloride channel inactivation by the coupled action of intracellular chloride and extracellular protons

(2010) Carmen Y. Hernández-Carballo et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of TMEM16A Chloride Channel Properties by Alternative Splicing

(2009) Loretta Ferrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart

(2009) Dayue Duan   JOURNAL OF PHYSIOLOGY-LONDON

Functional interactions between P2X4and P2X7receptors from mouse salivary epithelia

(2009) Griselda Casas-Pruneda et al.   JOURNAL OF PHYSIOLOGY-LONDON

TMEM16B induces chloride currents activated by calcium in mammalian cells

(2009) Simone Pifferi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification

(2009) Aaron B. Stephan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains

(2008) Jennie Garcia-Olivares et al.   JOURNAL OF PHYSIOLOGY-LONDON

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE