Rad and Rem are non-canonical G-proteins with respect to the regulatory role of guanine nucleotide binding in CaV1.2 channel regulation

Small G Proteins in the Cardiovascular System: Physiological and Pathological Aspects

(2013) Gervaise Loirand et al.   PHYSIOLOGICAL REVIEWS

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing

(2013) P. Subramanyam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rad GTPase Deletion Increases L‐type Calcium Channel Current Leading to Increased Cardiac Contraction

(2013) Janet R. Manning et al.   Journal of the American Heart Association

Structure of the GDP-bound G domain of the RGK protein Rem2

(2012) Philippe Reymond et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Regulation of voltage-dependent calcium channels by RGK proteins

(2012) Tingting Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Rem-GTPase regulates cardiac myocyte L-type calcium current

(2012) Janos Magyar et al.   Channels

Distinct RGK GTPases Differentially Use α1- and Auxiliary β-Binding-Dependent Mechanisms to Inhibit CaV1.2/CaV2.2 Channels

(2012) Tingting Yang et al.   PLoS One

RGK Family G-Domain:GTP Analog Complex Structures and Nucleotide-Binding Properties

(2011) Yehezkel Sasson et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the Dominant Negative S17N Mutant of Ras,

(2010) Nicolas Nassar et al.   BIOCHEMISTRY

Regulation of calcium channels by RGK proteins

(2010) Robyn Flynn et al.   Channels

Molecular Mechanisms, and Selective Pharmacological Rescue, of Rem-Inhibited Ca V 1.2 Channels in Heart

(2010) Xianghua Xu et al.   CIRCULATION RESEARCH

Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase

(2010) Tingting Yang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rad As a Novel Regulator of Excitation–Contraction Coupling and β-Adrenergic Signaling in Heart

(2009) Gang Wang et al.   CIRCULATION RESEARCH

Primary Culture of Adult Rat Heart Myocytes

(2009) Xianghua Xu et al.   Jove-Journal of Visualized Experiments

Alanine-Scanning Mutagenesis Defines a Conserved Energetic Hotspot in the CaVα1 AID-CaVβ Interaction Site that Is Critical for Channel Modulation

(2008) Filip Van Petegem et al.   STRUCTURE

The RGK family of GTP-binding proteins: Regulators of voltage-dependent calcium channels and cytoskeleton remodeling

(2007) Robert N. Correll et al.   CELLULAR SIGNALLING