Article
Biochemistry & Molecular Biology
Natcha Rasitanon, Kornautchaya Veenuttranon, Hnin Thandar Lwin, Kanyawee Kaewpradub, Tonghathai Phairatana, Itthipon Jeerapan
Summary: This study successfully integrated glucose oxidase (GOx) with nanomaterial-modified electrodes using egg white proteins, and demonstrated the potential of this biocompatible interface in bioelectronics, such as glucose sensors and biofuel cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Energy & Fuels
Aimi Yoshida, Seiya Tsujimura
Summary: This study investigates the impact of varying anions in an electrolyte solution on current generation by a redox hydrogel electrode. Different anions either increase or decrease the catalytic current generated by the electrode, with chaotropic anions like nitrate and chloride affecting FAD-GDH and GOx electrodes differently. Adsorption of anions onto the enzyme surface can induce a negative charge, altering electrostatic interactions and influencing current generation. Hydrogel shrinkage due to kosmotropic anions like sulphate and phosphate can increase catalytic current by changing enzyme and mediator concentrations within the hydrogel architecture. Understanding ion identity is crucial for designing high-performance redox hydrogel electrodes.
JOURNAL OF PHYSICS-ENERGY
(2021)
Article
Electrochemistry
Franziska Schachinger, Su Ma, Roland Ludwig
Summary: The redox potential is important for the rational use of oxidoreductases as bioelectrocatalysts. In this study, the redox potential of glucose dehydrogenase (GDH), which is widely used in glucose biosensors, was determined. The low redox potential of GDH can be used to develop glucose oxidizing bioanodes with a low operating potential, reducing susceptibility to electroactive substances in glucose biosensors or increasing the cell voltage in biofuel cells.
ELECTROCHEMISTRY COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Lucia Simona Ferraraccio, Paolo Bertoncello
Summary: In this study, dehydrogenase enzymes for glucose and lactate were encapsulated in alginate hydrogels and deposited on glassy carbon electrodes. These enzyme modified alginate hydrogels were used as electrochemiluminescence (ECL)-based biosensors for the detection of glucose and lactate. The ECL response was obtained through the redox reaction between the substrate, NAD+, and the encapsulated enzyme. The results suggest that the encapsulated dehydrogenases have potential for the development of biocompatible sensors for glucose and lactate detection in physiological fluids.
BIOELECTROCHEMISTRY
(2023)
Article
Physics, Applied
Cheong Hoon Kwon, Minchul Kang, Minseong Kwon, Donghyeon Nam, Yongkwon Song, Euiju Yong, Min-Kyu Oh, Yongju Kim, Bongjun Yeom, Jun Hyuk Moon, Seung Woo Lee, Jinhan Cho
Summary: This study demonstrates the use of a unique amphiphilic assembly method to generate hybrid biofuel cells with high power output and good operational stability. The assembled biofuel cell exhibits remarkably high power output (7.3 mW cm(-2)) and good operational durability.
APPLIED PHYSICS REVIEWS
(2022)
Article
Biochemistry & Molecular Biology
Takumi Yanase, Junko Okuda-Shimazaki, Ryutaro Asano, Kazunori Ikebukuro, Koji Sode, Wakako Tsugawa
Summary: The aim of this research is to develop a versatile method for creating a DET-type oxidoreductase complex based on the SpyCatcher/SpyTag technique. By combining SpyCatcher-fused heme c and SpyTag-fused non-DET-type oxidoreductases, DET-type oxidoreductase complexes with retained enzymatic activity and electron transfer ability to the electrode were successfully formed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Shoichi Nishitani, Tiffany Tran, Andrew Puglise, Sounghyun Yang, Markita P. Landry
Summary: This study presents the development of near-infrared fluorescent single-walled carbon nanotube (SWCNT) based nanosensors for glucose imaging. The authors find that the fluorescence modulation of GOx-SWCNT is not associated with the enzymatic activity but rather triggered by the substrate-enzyme binding. Leveraging this unique mechanism, the authors developed catalytically inactive nanosensors that enable glucose imaging in mouse brain slices.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Immunology
Alexia Dumas, Ulla G. Knaus
Summary: Redox medicine is a new therapeutic concept targeting reactive oxygen species (ROS) and their secondary reaction products. Selective strategies for intervention are needed, especially in inflammatory diseases where source-specific inhibitors of ROS may be more beneficial.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Jana M. Becker, Anna Lielpetere, Julian Szczesny, Sabrina Bichon, Sebastien Gounel, Nicolas Mano, Wolfgang Schuhmann
Summary: A new redox polymer/bilirubin oxidase-based gas diffusion electrode has been developed as a non-current and non-stability limiting biocathode in a glucose/O2 biofuel cell, serving as a self-powered glucose biosensor.
BIOELECTROCHEMISTRY
(2023)
Review
Chemistry, Analytical
Lynette Alvarado-Ramirez, Magdalena Rostro-Alanis, Jose Rodriguez-Rodriguez, Juan Eduardo Sosa-Hernandez, Elda M. Melchor-Martinez, Hafiz M. N. Iqbal, Roberto Parra-Saldivar
Summary: The use of sensors in critical areas such as water, food, and health has increased in recent decades, especially biosensors based on enzymes have emerged as reliable, sensitive, and selective tools. With advancements in nanotechnology, enzyme-based biosensors have the capability to detect multiple analytes, showing promise in the field of biosensors.
Review
Biochemical Research Methods
Oren Bachar, Roy Cohen, Matan M. Meirovich, Yifat Cohen, Omer Yehezkeli
Summary: The advances in biotic-abiotic interfaced systems have great potential in bioanalytics and biocatalysis applications. The combination of nanoelements' unique electronic and optic properties with the selectivity and catalytic abilities of biotic materials can lead to superior features. These new nanobiohybrids may contribute to addressing global challenges such as alternative energy utilization and affordable biodiagnostics and therapeutics tools.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Paulina K. Wells, Oleh Smutok, Zhong Guo, Kirill Alexandrov, Evgeny Katz
Summary: Advances in protein engineering have made it possible to create protein biosensors as alternatives to analytical and diagnostic methods. This study focuses on the construction of a protein biosensor array using an artificial variant of PQQ-glucose dehydrogenase, which addresses the challenges of sensitivity, multiplexing, and manufacturability. By immobilizing GDH protein on silica nanoparticles and monitoring changes in fluorescence, a highly sensitive biosensor array with low background and a wide dynamic range has been successfully developed for quantitative detection of drugs in biological fluids.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Natcha Rasitanon, Parinthorn Rattanapan, Kanyawee Kaewpradub, Chittanon Buranachai, Itthipon Jeerapan
Summary: This article introduces a strategy to synthesize functional biorecognition microparticles by combining proteins with glucose oxidase, which can be directly applied to printed electrodes and exhibit good performance in electrochemical biosensors. Utilizing food-based proteins to accommodate enzymes and create redox-active microparticles for catalyzing glucose oxidation offers advantages in developing affordable and degradable bioelectrodes. This concept holds promise for advancing biocompatible electrodes in biosensor and bioelectronics applications.
Review
Biochemical Research Methods
Zhiguang Zhu, Haiyan Song, Yuanming Wang, Yi-Heng P. J. Zhang
Summary: The development of electrochemical biosensors has received significant attention, with protein engineering being used to enhance the properties of redox enzymes for applicable biosensors. This review focuses on recent advances in protein engineering for improving enzymatic catalysis, facilitating electron transfer and enzyme immobilization, and constructing allosteric protein biosensors. The pros and cons of different protein engineering strategies are briefly discussed, along with future perspectives.
CURRENT OPINION IN BIOTECHNOLOGY
(2022)
Article
Biophysics
Kavita Jayakumar, Anna Lielpetere, Daniel A. Domingo-Lopez, Ruth E. Levey, Garry P. Duffy, Wolfgang Schuhmann, Donal Leech
Summary: Foreign body response (FBR) is a challenge for implantable biosensors and medical devices. Zwitterionic polymers (ZPs) show promise in reducing biofouling. A ZP containing MPC was found to effectively resist fibrinogen adsorption and fibroblast adhesion, while maintaining sensor performance.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Electrochemistry
Tien D. Le, Lin Zhang, Stephane Reculusa, Gerard Vignoles, Nicolas Mano, Alexander Kuhn, Didier Lasseux
Article
Chemistry, Multidisciplinary
Claire Stines-Chaumeil, Francois Mavre, Brice Kauffmann, Nicolas Mano, Benoit Limoges
Article
Chemistry, Multidisciplinary
Adrian Ruff, Julian Szczesny, Maria Vega, Sonia Zacarias, Pedro M. Matias, Sebastien Gounel, Nicolas Mano, Ines A. C. Pereira, Wolfgang Schuhmann
Article
Materials Science, Multidisciplinary
A. Baux, G. Couegnat, G. L. Vignoles, D. Lasseux, A. Kuhn, C. Carucci, N. Mano, T. D. Le
MATERIALS & DESIGN
(2020)
Article
Engineering, Chemical
T. D. Le, D. Lasseux, L. Zhang, C. Carucci, S. Gounel, S. Bichon, F. Lorenzutti, A. Kuhn, T. Safarik, N. Mano
Summary: This work focuses on a multi-scale modeling of coupled diffusion and reaction in a porous micro electrode operating in the Direct Electron Transfer mode. By developing and validating the model, it provides an operational simple way of understanding and further optimizing the functioning of porous electrodes in DET mode.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Alina Sekretareva, Shiliang Tian, Sebastien Gounel, Nicolas Mano, Edward Solomon
Summary: High-potential multicopper oxidases (MCOs) are efficient catalysts for oxygen reduction with low overpotentials and commonly used in biofuel cells. This study investigated the electron transfer pathways in MCO electrocatalysis and found that electron transfer primarily occurs through the T1 site to the trinuclear copper cluster (TNC). The research provides insights into the factors controlling the kinetics of MCO electrocatalysis and guidance for designing more efficient biocathodes for the ORR.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Serena Arnaboldi, Gerardo Salinas, Aleksandar Karajic, Patrick Garrigue, Tiziana Benincori, Giorgia Bonetti, Roberto Cirilli, Sabrina Bichon, Sebastien Gounel, Nicolas Mano, Alexander Kuhn
Summary: One key method for designing bioinspired machines is transferring concepts from nature to man-made structures by integrating biomolecules into artificial mechanical systems, allowing the conversion of molecular information into macroscopic action. Hybrid bioelectrochemical swimmers can convert chiral information into enantiospecific macroscopic trajectories, with potential biomedical applications and food quality testing.
Article
Electrochemistry
Taiki Adachi, Ievgen Mazurenko, Nicolas Mano, Yuki Kitazumi, Kunishige Kataoka, Kenji Kano, Keisei Sowa, Elisabeth Lojou
Summary: This study investigated the effects of Cu2+ on the bioelectrocatalytic reduction of O2 by CueO, and found that Cu2+ decreased the activity of CueO and caused inactivation and reactivation processes. Kinetic analysis and pseudo-steady-state analysis revealed the relationship between Cu2+ and the enzymatic activity.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Tatjana Safarik, Aleksandar Karajic, Stephane Reculusa, Philip N. Bartlett, Nicolas Mano, Alexander Kuhn
Summary: This study reports the electrochemical elaboration and characterization of a 3D coaxial macroporous twin-electrode, which is obtained by a low-cost bottom-up approach using nanoengineered highly organized porous material. The resulting electrode architecture allows for signal amplification in electroanalytical measurements and has potential applications in various (bio)electroanalytical fields.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Jana M. Becker, Anna Lielpetere, Julian Szczesny, Sabrina Bichon, Sebastien Gounel, Nicolas Mano, Wolfgang Schuhmann
Summary: A new redox polymer/bilirubin oxidase-based gas diffusion electrode has been developed as a non-current and non-stability limiting biocathode in a glucose/O2 biofuel cell, serving as a self-powered glucose biosensor.
BIOELECTROCHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Serena Arnaboldi, Gerardo Salinas, Sabrina Bichon, Sebastien Gounel, Nicolas Mano, Alexander Kuhn
Summary: This study introduces an autonomous bi-enzymatic system that utilizes the spontaneous oxidation and reduction of glucose and oxygen to trigger reversible motion. The system operates without the need for any external trigger, relying on the asymmetric uptake and release of ions on a conducting polymer strip that houses glucose oxidase and bilirubin oxidase enzymes. The time-asymmetric consumption of both fuels by the enzymatic reactions leads to the autonomous actuation of the device.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Sabrina Bichon, Priscilla Staigre, Sebastien Gounel, Tatjana Safarik, Cristina Carucci, Alexander Kuhn, Nicolas Mano
Summary: The researchers have developed a strategy to stabilize and maintain enzyme activity in mixed-solvent systems by using engineered enzymes and tuned osmium-based redox polymers. They have validated this approach and demonstrated the wide applicability of the electrode in various organic solvents.
JOURNAL OF CATALYSIS
(2023)
Article
Engineering, Electrical & Electronic
Luigi Di Trocchio, Cristina Carucci, Kotagudda Ranganath Sindhu, Chloe Morel, Jean Luc Lachaud, Sabrina Bichon, Sebastien Gounel, Nicolas Mano, Claudine Boiziau, Corinne Dejous, Alexander Kuhn, Simon Hemour
Summary: This study introduces a light, battery-less, and wireless strategy for continuous monitoring of an implanted biofuel cell in laboratory rats by utilizing a Radio Frequency Identification (RFID) link. The lightweight and flexible tag antenna presented in the work has communication capability above 60 cm in a field environment, and operational capabilities were demonstrated through 24-hour continuous monitoring of an enzymatic glucose/O-2 reaction both in vitro and in vivo.
IEEE JOURNAL OF ELECTROMAGNETICS RF AND MICROWAVES IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Physical
Aleksandar Karajic, Pascal Merzeau, Emmanuel Suraniti, Sebastien Gounel, Christele Jaillet, Alexander Kuhn, Nicolas Mano
ACS APPLIED ENERGY MATERIALS
(2020)
Review
Chemistry, Physical
Nicolas Mano
CURRENT OPINION IN ELECTROCHEMISTRY
(2020)
Article
Electrochemistry
Abdul Qayoom Mugheri, Shaista Khan, Ali Asghar Sangah, Aijaz Ahmed Bhutto, Muhammad Younis Laghari, Nadeem Ahmed Mugheri, Asif Ali Jamali, Arsalan Ahmed Mugheri, Nagji Sodho, Abdul Waheed Mastoi, Aftab Kandhro
Summary: Green hydrogen has the potential to transition to a pollution-free energy infrastructure. This study proposes a solution to produce hydrogen during the photoelectrochemical process, offering greater stability and control over chemical reactions. Techno-economic assessments show the efficiency and economic feasibility of co-producing value-added chemicals to enhance green hydrogen production.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Danpeng Cheng, Wuxin Sha, Qigao Han, Shun Tang, Jun Zhong, Jinqiao Du, Jie Tian, Yuan-Cheng Cao
Summary: LiNixCoyMn1-x-yO2 (NCM) is a critical cathode material for lithium-ion batteries in electric vehicles. The aging of cathode/electrolyte interfaces leads to capacity degradation and long-term cycle instability. A novel neural network model called ACGNet is developed to predict electrochemical stability windows of crystals, allowing for high-throughput screening of coating materials. LiPO3 is identified as a promising coating material with high oxidation voltage and low cost, which significantly improves the cycle stability of NCM batteries. This study demonstrates the accuracy and potential of machine learning in battery materials.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
P. Mohana, R. Yuvakkumar, G. Ravi, S. Arunmetha
Summary: This study successfully fabricates a non-noble CuO/NiO/rGO nanocomposite and investigates its electrocatalytic performance for oxygen evolution reaction in alkaline environment. The experimental results demonstrate that the electrocatalyst exhibits high activity and good stability, offering a new synthetic approach for sustainable energy production.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Qiong Qu, Jing Guo, Hongyu Wang, Kai Zhang, Jingde Li
Summary: In this study, a bifunctional electrode host design consisting of carbon nanofibers implanted ordered porous Co-decorated Al2O3 supported on carbon nanotube film (CNTF) was proposed to address the shuttling effect of lithium polysulfides (LiPSs) and dendrite formation of metal lithium anode in lithium-sulfur (Li-S) batteries. The electrode exhibited excellent conductivity, efficient confinement of LiPSs, and catalytic conversion performance, resulting in high initial capacity and good capacity retention during cycling. As an anode, the electrode showed excellent Li+ diffusion performance and uniform lithium growth behavior, achieving a dendrite-free lithium electrode. The flexible pack cell assembled from these electrodes delivered a specific capacity of 972 mAh g(-1) with good capacity retention.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Hong Zhang, Jin-Peng Yu, Chen Chen, Cheng-Yong Shu, Guang-Yu Xu, Jie Ren, Kai Cui, Wen-Fang Cai, Yun-Hai Wang, Kun Guo
Summary: Spray coating of acetylene black nanoparticles onto stainless steel mesh can enhance its biofilm formation ability and current density, making it a promising electrode material for microbial electrochemical systems. The spray coating method is simple, cost-effective, and suitable for large-size stainless steel electrodes.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Binpeng Hou, Jingjin Chen, Li-Hong Zhang, Xiaowen Shi, Zizhong Zhu
Summary: The electrochemical performance of Li1.20Mn0.44Ni0.32Co0.04O2 and its oxygen-deficient phase Li1.20Mn0.44Ni0.32Co0.04O1.83 was studied through first-principles calculations. The results show that the oxygen-deficient phase has a higher theoretical capacity but lower voltage platform and higher chemical activity compared to the pristine phase.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Yating Du, Sayoko Shironita, Daisuke Asakura, Eiji Hosono, Yoshitsugu Sone, Yugo Miseki, Eiichi Kobayashi, Minoru Umeda
Summary: This study investigates the effect of high- and low-temperature environments on the charge-discharge performance of a Li-ion battery. The deterioration mechanisms of the battery at different temperatures are analyzed through various characterization techniques. The results indicate that the battery performance deteriorates more significantly at a low-temperature environment of 5 degrees C compared to higher temperatures. The understanding of the deterioration mechanisms can contribute to the development of safer battery usage methods.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Si-Si Shi, Zhi-Xiang Yuan, Fei Zhang, Ping Chen
Summary: In this study, a new nano-electrocatalyst was prepared, which exhibited superior electrocatalytic activity for the reduction of NO2- to ammonia in a neutral electrolyte, potentially due to the synergistic enhancement between Co3O4-x and Co.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Berna Dalkiran, Havva Bekirog
Summary: This study reports the use of deep eutectic solvents (DES) based on ethylene glycol and urea as low-cost and green electrolytes for enhancing electrochemical detection of natural antioxidants. The study successfully developed a disposable and effective electrochemical sensing platform for simultaneous determination of ascorbic acid (AA) and gallic acid (GA) using NaOH nanorods on a pencil graphite electrode. The proposed electrode showed improved analytical performance, with higher peak currents and shifted oxidation potentials in DES compared to BR buffer medium.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Sijun Ren, Jianguo Huang
Summary: In this study, a novel bio-inspired nanofibrous WO3/carbon composite was synthesized using a facile hydrothermal method. The three-dimensional network structure of the composite alleviated the volume expansion of WO3 nanorods and enhanced the charge-transport kinetics. The optimized composite exhibited superior lithium storage properties.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Zhilong Zheng, Yu Chen, Hongxia Yin, Hengbo Xiao, Xiangji Zhou, Zhiwen Li, Ximin Li, Jin Chen, Songliu Yuan, Junjie Guo, Haibin Yu, Zhen Zhang, Lihua Qian
Summary: This study found that interstitial Zn cations in CoMoO4 can modulate the dissolution kinetics of Mo cations and improve the OER performance. The interstitial Zn cations can prevent the dissolution of Co cations at high potential, enhancing the durability of the catalyst.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Xiaobo Lin, Shern R. Tee, Debra J. Searles, Peter T. Cummings
Summary: Molecular dynamics simulations using the constant potential method were used to investigate the charging dynamics and charge storage of supercapacitors. The simulations revealed that the water-in-salt electrolyte exhibited the highest charge storage and significantly higher capacitance on the negative electrode. The varying contributions of different electrode regions to supercapacitor performance were also demonstrated.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Wiktoria Lipinska, Vita Saska, Katarzyna Siuzdak, Jakub Karczewski, Karol Zaleski, Emerson Coy, Anne de Poulpiquet, Ievgen Mazurenko, Elisabeth Lojou
Summary: The spatial distribution of enzymes on electrodes is important for bioelectrocatalysis. In this study, controlled spatial distribution of gold nanoparticles on Ti nanodimples was achieved. The efficiency of enzymatic O2 reduction was found to be influenced by the size of the gold nanoparticles and their colocalization with TiO2. The highest stability of enzymatic current was observed with the largest gold nanoparticles.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Tariq M. Al-Hejri, Zeenat A. Shaikh, Ahmed H. Al-Naggar, Siddheshwar D. Raut, Tabassum Siddiqui, Hamdan M. Danamah, Vijaykumar V. Jadhav, Abdullah M. Al-Enizi, Rajaram S. Mane
Summary: This study explores a promising self-growth approach for the synthesis of nickel hydroxide (Ni(OH)2) nanosponge-balls on the surface of a nickel-foam (NiF) electrode. The modified NiF electrode, named Ni(OH)2@NiF, shows distinctive nanosponge-ball morphology and demonstrates excellent energy storage capability and electrocatalytic performance in both hydrogen and oxygen evolution reactions.
ELECTROCHIMICA ACTA
(2024)
Article
Electrochemistry
Rafael Del Olmo, Gregorio Guzman-Gonzalez, Oihane Sanz, Maria Forsyth, Nerea Casado
Summary: The use of Lithium-Ion Batteries (LIBs) is becoming increasingly extensive, and it is important to optimize the devices to achieve their maximum practical specific capacity. In this study, mixed ionic-electronic conducting (MIEC) binders based on PEDOT:PSS and PEDOT: PDADMA-TFSI were developed for Li-ion cathodes, and their performance was compared with conventional formulations. The influence of electrode formulations, including the addition of conducting carbon and an Organic Ionic Plastic Cristal (OIPC), was also analyzed. The proposed binders showed improved performance compared to conventional formulations with different electrolyte types and active materials.
ELECTROCHIMICA ACTA
(2024)
