The correlation between Topoisomerase-1 (Topo1) expression and outcome of treatment with capecitabine and irinotecan in advanced colorectal cancer (ACC) patients (pts) treated in the CAIRO study of the Dutch Colorectal Cancer Group (DCCG)
EJC SUPPLEMENTS (2009)
Journal
EJC SUPPLEMENTS
Volume 7, Issue 2, Pages 321-322Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Keywords
Categories
Ask authors/readers for more resources
Authors
I am an author on this paper
Reviews
Recommended
Effectiveness and safety of capecitabine, irinotecan and panitumumab in advanced colorectal cancer
Pui Lam Yip, Wai Him Brian Fung, Francis Ann Shing Lee, Chak Fei Lee, Natalie Sean Man Wong, Shing Fung Lee
FRONTIERS IN ONCOLOGY (2023)
Bevacizumab plus capecitabine as later-line treatment for patients with metastatic colorectal cancer refractory to irinotecan, oxaliplatin, and fluoropyrimidines
Yeong Hak Bang, Jeong Eun Kim, Ji Sung Lee, Sun Young Kim, Kyu-Pyo Kim, Tae Won Kim, Yong Sang Hong
SCIENTIFIC REPORTS (2021)
Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer
Hiroyuki Arai, Yi Xiao, Joshua Millstein, Jingyuan Wang, Francesca Battaglin, Natsuko Kawanishi, Priya Jayachandran, Shivani Soni, Wu Zhang, Christoph Mancao, Bodour Salhia, Shannon M. Mumenthaler, Aparna R. Parikh, Heinz-Josef Lenz
BRITISH JOURNAL OF CANCER (2022)
Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer
Seobin Yoon, Bum-Kyu Lee, Keun Pil Kim
PHYTOMEDICINE (2023)
Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study
Xiu Liu, Kai Ou, Xiaoting Ma, Lizhen Gao, Qi Wang, Haizeng Zhang, Lin Yang
BMC CANCER (2022)
Activity of Sorafenib Plus Capecitabine in Previously Treated Metastatic Colorectal Cancer
Thomas J. George, Alison M. Ivey, Azka Ali, Ji-Hyun Lee, Yu Wang, Karen C. Daily, Brian H. Ramnaraign, Sanda A. Tan, Krista P. Terracina, Thomas E. Read, Long H. Dang, Atif Iqbal
ONCOLOGIST (2021)
LEF1 silencing sensitizes colorectal cancer cells to oxaliplatin, 5-FU, and irinotecan
Elham Fakhr, Fatemeh Zare, Kayhan Azadmanesh, Ladan Teimoori-Toolabi
BIOMEDICINE & PHARMACOTHERAPY (2021)
Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase
Bei Yue, Ruiyang Gao, Cheng Lv, Zhilun Yu, Hao Wang, Xiaolong Geng, Zhengtao Wang, Wei Dou
FRONTIERS IN PHARMACOLOGY (2021)
Translational Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Oxaliplatin and Irinotecan in Colorectal Cancer
Jinwei Zhu, Yicui Zhang, Yixin Zhao, Jingwei Zhang, Kun Hao, Hua He
PHARMACEUTICS (2023)
Combining gut microbiota modulation and chemotherapy by capecitabine-loaded prebiotic nanoparticle improves colorectal cancer therapy
Tianqun Lang, Runqi Zhu, Xiao Zhu, Wenlu Yan, Yu Li, Yihui Zhai, Ting Wu, Xin Huang, Qi Yin, Yaping Li
NATURE COMMUNICATIONS (2023)
Advanced colorectal cancer subtypes (aCRCS) help select oxaliplatin-based or irinotecan-based therapy for colorectal cancer
Shin Takahashi, Yasuhiro Sakamoto, Tadamichi Denda, Atsuo Takashima, Yoshito Komatsu, Masato Nakamura, Hisatsugu Ohori, Tatsuro Yamaguchi, Yoshimitsu Kobayashi, Hideo Baba, Masanori Kotake, Kenji Amagai, Hitoshi Kondo, Ken Shimada, Atsushi Sato, Satoshi Yuki, Akira Okita, Kota Ouchi, Keigo Komine, Mika Watanabe, Satoshi Morita, Chikashi Ishioka
CANCER SCIENCE (2021)
Integrated Bioinformatics Analysis of the Hub Genes Involved in Irinotecan Resistance in Colorectal Cancer
Jakub Kryczka, Joanna Boncela
BIOMEDICINES (2022)
Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
Pietro Paolo Vitiello, Giulia Martini, Luigi Mele, Emilio Francesco Giunta, Vincenzo De Falco, Davide Ciardiello, Valentina Belli, Claudia Cardone, Nunzia Matrone, Luca Poliero, Virginia Tirino, Stefania Napolitano, Carminia Della Corte, Francesco Selvaggi, Gianpaolo Papaccio, Teresa Troiani, Floriana Morgillo, Vincenzo Desiderio, Fortunato Ciardiello, Erika Martinelli
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
Cytotoxic T-Lymphocyte Antigen-4 in Colorectal Cancer: Another Therapeutic Side of Capecitabine
Afshin Derakhshani, Shahryar Hashemzadeh, Zahra Asadzadeh, Mahdi Abdoli Shadbad, Farnaz Rasibonab, Hossein Safarpour, Vahid Jafarlou, Antonio Giovanni Solimando, Vito Racanelli, Pankaj Kumar Singh, Souzan Najafi, Darya Javadrashid, Oronzo Brunetti, Nicola Silvestris, Behzad Baradaran
CANCERS (2021)
Adjuvant Capecitabine and Oxaliplatin for Elderly Patients with Colorectal Cancer
Kazuaki Okamoto, Hiroaki Nozawa, Shigenobu Emoto, Koji Murono, Kazuhito Sasaki, Soichiro Ishihara
ONCOLOGY (2022)
Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer
Louise C. Brown, Janet Graham, David Fisher, Richard Adams, Jenny Seligmann, Matthew Seymour, Richard Kaplan, Emma Yates, Mahesh Parmar, Susan D. Richman, Philip Quirke, Rachel Butler, Kaikeen Shiu, Gary Middleton, Leslie Samuel, Richard H. Wilson, Timothy S. Maughan
CLINICAL TRIALS (2022)
FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing
Susan D. Richman, Gemma Hemmings, Helen Roberts, Niall Gallop, Rachel Dodds, Lyndsay Wilkinson, Jonathan Davis, Rhian White, Emma Yates, Bharat Jasani, Louise Brown, Tim S. Maughan, Rachel Butler, Philip Quirke, Richard Adams
JOURNAL OF CLINICAL PATHOLOGY (2023)
Spend less to achieve more: Economic analysis of intermittent versus continuous cetuximab in KRAS wild-type patients with metastatic colorectal cancer
Raymond H. Henderson, Declan French, Ethna McFerran, Richard Adams, Harpreet Wasan, Robert Glynne-Jones, David Fisher, Susan Richman, Philip D. Dunne, Lisa Wilde, Timothy S. Maughan, Richard Sullivan, Mark Lawler
JOURNAL OF CANCER POLICY (2022)
Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial
Dion Morton, Matthew Seymour, Laura Magill, Kelly Handley, James Glasbey, Bengt Glimelius, Andy Palmer, Jenny Seligmann, Soren Laurberg, Keigo Murakami, Nick West, Philip Quirke, Richard Gray, FOxTROT Collaborative Grp
JOURNAL OF CLINICAL ONCOLOGY (2023)
FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty
J. R. Platt, O. M. Todd, P. Hall, Z. Craig, A. Quyn, M. Seymour, M. Braun, J. Roodhart, C. Punt, N. Christou, J. Taieb, M. Karoui, J. Brown, D. A. Cairns, D. Morton, A. Gilbert, J. F. Seligmann
ESMO OPEN (2023)
Female Sex but Not Oestrogen Receptor Expression Predicts Survival in Advanced Gastroesophageal Adenocarcinoma-A Post-hoc Analysis of the GO2 Trial
Mark A. Baxter, Lindsay C. Spender, Shaun Walsh, Susan Bray, Gemma Skinner, Sharon S. King, Peter S. Hall, Matthew J. Seymour, Russell D. Petty
CANCERS (2023)
Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study
Jan Moritz Niehues, Philip Quirke, Nicholas P. West, Heike I. Grabsch, Marko van Treeck, Yoni Schirris, Gregory P. Veldhuizen, Gordon G. A. Hutchins, Susan D. Richman, Sebastian Foersch, Titus J. Brinker, Junya Fukuoka, Andrey Bychkov, Wataru Uegami, Daniel Truhn, Hermann Brenner, Alexander Brobeil, Michael Hoffmeister, Jakob Nikolas Kather
CELL REPORTS MEDICINE (2023)
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study
Sophia J. Wagner, Daniel Reisenbuechler, Nicholas P. West, Jan Moritz Niehues, Jiefu Zhu, Sebastian Foersch, Gregory Patrick Veldhuizen, Philip Quirke, Heike I. Grabsch, Piet A. van den Brandt, Gordon G. A. Hutchins, Susan D. Richman, Tanwei Yuan, Rupert Langer, Josien C. A. Jenniskens, Kelly Offermans, Wolfram Mueller, Richard Gray, Stephen B. Gruber, Joel K. Greenson, Gad Rennert, Joseph D. Bonner, Daniel Schmolze, Jitendra Jonnagaddala, Nicholas J. Hawkins, Robyn L. Ward, Dion Morton, Matthew Seymour, Laura Magill, Marta Nowak, Jennifer Hay, Viktor H. Koelzer, David N. Church, Christian Matek, Carol Geppert, Chaolong Peng, Cheng Zhi, Xiaoming Ouyang, Jacqueline A. James, Maurice B. Loughrey, Manuel Salto-Tellez, Hermann Brenner, Michael Hoffmeister, Daniel Truhn, Julia A. Schnabel, Melanie Boxberg, Tingying Peng, Jakob Nikolas Kather
CANCER CELL (2023)
Reply to S. Chakrabarti et al, R. Cohen et al, and DC Guven
Richard Gray, Matt Seymour, Laura Magill, Kelly Handley, Philip Quirke, Nick West, Dion Morton
JOURNAL OF CLINICAL ONCOLOGY (2023)
The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC).
Jenny F. Seligmann, Enric Domingo, David Fisher, Faye Elliott, Louise C. Brown, Matthew T. Seymour, Susan Richman, Philip Quirke, Rachel Butler, Helen Roberts, Carme Camps, Pamela Kaisaki, David N. Church, David James Kerr, Rachel Kerr, Richard H. Wilson, Oliver Sieber, Jenny Taylor, Ian Tomlinson, Tim Maughan
JOURNAL OF CLINICAL ONCOLOGY (2022)
A biomarker enrichment trial of anti-EGFR agents in right primary tumor location (rPTL), RAS wild-type (RAS-wt) advanced colorectal cancer (aCRC): ARIEL (ISRCTN11061442)
Christopher Williams, Jake Emmerson, Andrew David Beggs, Nicholas West, John A. Bridgewater, Janet Graham, Matthew T. Seymour, Gemma Hemmings, Claire Dimbleby, Geraldine A. Murden, Alexandra Gilbert, David M. Meads, David A. Cairns, Richard Adams, Jenny F. Seligmann
JOURNAL OF CLINICAL ONCOLOGY (2022)
Metastatic Colorectal Cancer Outcomes by Age Among ARCAD First-and Second-Line Clinical Trials
Nadine J. McCleary, William S. Harmsen, Ellana Haakenstad, James M. Cleary, Jeffrey A. Meyerhardt, John Zalcberg, Richard Adams, Axel Grothey, Alberto F. Sobrero, Eric Van Cutsem, Richard M. Goldberg, Marc Peeters, Josep Tabernero, Matt Seymour, Leonard B. Saltz, Bruce J. Giantonio, Dirk Arnold, Mace L. Rothenberg, Miriam Koopman, Hans-Joachim Schmoll, Henry C. Pitot, Paulo M. Hoff, Niall Tebbutt, Gianluca Masi, John Souglakos, Carsten Bokemeyer, Volker Heinemann, Takayuki Yoshino, Benoist Chibaudel, Aimery deGramont, Qian Shi, Stuart M. Lichtman
JNCI CANCER SPECTRUM (2022)