Article
Chemistry, Physical
Bahar Kanci Bozoglan, Osman Duman, Sibel Tunc
Summary: New OXI-loaded hydrogels with high antifungal activity were developed for onychomycosis treatment. The release of OXI from the hydrogels can be controlled by adjusting the amount of MMT in the hydrogel matrix.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Biochemistry & Molecular Biology
Parinaz Jabbari, Gholam Reza Mahdavinia, Parisa Fathi Rezaei, Bagher Kazemi Heragh, Parisa Labib, Hessam Jafari, Shahrzad Javanshir
Summary: A nanocomposite carrier with double-responsive features was developed by integrating magnetic montmorillonite into a chitosan matrix and crosslinking it with citric acid. The carrier showed high sustained release and antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Fahimeh Farshi Azhar, Mehrnoush Rezaei, Ali Olad, Hanieh Mousazadeh
Summary: The study demonstrated a significant synergistic effect of GO and MMT on the controlled release of GEM, with the nanocomposite containing 17wt% MMT showing optimal drug release rate and content, with a T-50% of about 2 hours. Non-Fickian diffusion mechanism and Korsmeyer-Peppas kinetic model were used to confirm drug release behavior. Additionally, in vitro cytotoxicity assay confirmed the potential of the nanocomposite as a breast cancer therapy system for controlled delivery of GEM.
Article
Biochemistry & Molecular Biology
Bagher Kazemi Heragh, Shahrzad Javanshir, Gholam Reza Mahdavinia, Mohammad Reza Naimi Jamal
Summary: A pH-responsive drug carrier was developed for controllable drug release in the gastric environment by grafting hydroxyapatite into a chitosan/nano-clay matrix. The co-precipitation method led to the penetration of hydroxyapatite nanoparticles inside the matrix, reducing drug release rate. The nanocomposite showed high sensitivity to pH and significantly decreased drug release rate in both gastric and intestinal environments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Alamri Rahmah Dhahawi Ahmad, Saifullahi Shehu Imam, Rohana Adnan, Wen Da Oh, Ahmad Faiz Abdul Latip, Alomari Asma Dhahawi Ahmad
Summary: The aim of this study was to develop an economical and effective catalyst for wastewater remediation using the Fenton oxidation process. Fe3O4-montmorillonite alginate (FeMA) composite beads were synthesized and evaluated for the degradation of the antibiotic ofloxacin (OFL) in water. The FeMA composite beads showed higher surface area, porosity, and thermal stability compared to pristine alginate beads. The results demonstrated that FeMA composite beads can be a promising material for wastewater remediation via the Fenton oxidation process.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Gustavo Cabrera-Barjas, Liliam Becheran, Oscar Valdes, Ady Giordano, Rodrigo Segura-del Rio, Gaston Bravo-Arrepol, Esteban F. Duran-Lara, Juan Cea, Alex Berg, Johana Castanos, Saddys Rodriguez-Llamazares, Gast on Fuentes, Plamen Katsarov, Paolina Lukova, Cedric Delattre
Summary: The overuse of antibiotics can lead to the development of resistance to targeted bacteria. A controlled release system, such as the nanocomposite films prepared in this study, can provide a solution for achieving higher drug efficiency without overdosing and drug resistance. The films, made from chitosan reinforced with cellulose nanofibrils, showed promising properties for antibiotic release. The content of nanofibers in the film formulation affected the swelling capacity, stiffness, and tensile strength of the films, as well as the release rate of vancomycin, suggesting the potential application of these films for pharmaceutical purposes.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Physical
Zahra Shariatinia, Mahdieh Ziba
Summary: Chitosan was functionalized and utilized as smart pH-responsive drug delivery systems for the anticancer drug cyclophosphamide. Different synthesized materials showed varied drug release rates under different pH conditions, with CS-AC-U-CP being identified as the most desirable DDS.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Physical
Islam M. Minisy, Nehal A. Salahuddin, Mohamad M. Ayad
Summary: In this study, an eco-friendly adsorbent of chitosan-montmorillonite/polyaniline nanocomposite was synthesized and used for methylene blue removal from aqueous solutions. The polyaniline base composite proved to be a better dye adsorbent and exhibited a maximum adsorption capacity of 111 mg g-1.
APPLIED CLAY SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Khushbu, Vasudha Vaid, Kuljit Kaur, Ankush Panwar, Anupama Devi, Anshul Bansal, Rajeev Jindal
Summary: This study prepared an inclusion complex of chlorphenamine and montmorillonite and compared it with direct loading of the free drug. The results showed that the inclusion complex loaded nanocomposite had a high drug release concentration under different pH conditions, and diffusion and relaxation phenomena were the main mechanisms of drug release. The host-guest interactions of montmorillonite contributed to sustained drug release.
Article
Biochemical Research Methods
Zahra Sayyar, Gholam Reza Mahdavinia, Alireza Khataee
Summary: In this study, Chito/HA-mMMt hydrogels were prepared as drug carriers with sustained release behavior and pH-dependence, showing great potential for applications in drug delivery systems. The hydrogels also exhibited wound healing properties.
JOURNAL OF BIOLOGICAL ENGINEERING
(2023)
Article
Materials Science, Biomaterials
Hessam Jafari, Ziba Atlasi, Gholam Reza Mahdavinia, Somayeh Hadifar, Mohammad Sabzi
Summary: This study designed montmorillonite-incorporated pH-responsive and magnetic kappa-carrageenan/chitosan hydrogels for controlled release of sunitinib anticancer drug. The drug loading efficiency of nanocomposite hydrogels was increased by introducing montmorillonite, and the release was more efficient in acidic solutions for hydrogels containing a high content of magnetic montmorillonite.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Pegah Sanjarnia, Jhamak Nourmohammadi, Saeed Hesaraki
Summary: This research introduces a new wound dressing made from chitosan and copper-containing Janus nanoparticles (JNPs) that have antibacterial and anti-inflammatory properties. The JNPs were synthesized by attaching copper to PDA nanospheres and were embedded in chitosan at different concentrations. The resulting JNPs showed successful adhesion of Cu2+ ions and increased pore size and porosity with higher JNPs concentration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Rui Cui, Jiatong Yan, Jianxin Cao, Yuyue Qin, Minglong Yuan, Lin Li
Summary: This study aimed to prepare a controlled-release antibacterial food packaging film using chitosan and acidified modified montmorillonite loaded with CIN. The coordination of acid-MMt-CIN significantly enhanced the barrier properties of CS film, and the addition of acid-MMt-CIN had a significant inhibitory effect on Staphylococcus aureus and Escherichia coli. Overall, the CS/acid-MMt-CIN film showed potential as an antibacterial active food packaging film with improved UV resistance.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Materials Science, Biomaterials
Fahimeh Farshi Azhar, Aylin Ahmadinia, Hanieh Mousazadeh, Elnaz Kheirkhah
Summary: In this study, a pH-sensitive magnetic hydrogel nanocomposite was synthesized for extended release of methotrexate (MTX). The nanocomposite exhibited less burst release in the gastric and intestinal fluid, leading to the intact beads passing through the stomach and releasing the drug at a slower rate in the intestine. In breast cancer cells, the nanocomposite showed anti-proliferative and apoptotic effects.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Mohammadjavad Ahmadi, Mehrab Pourmadadi, Sohrab Ali Ghorbanian, Fatemeh Yazdian, Hamid Rashedi
Summary: Recent studies have focused on investigating the harmful side effects of chemotherapeutic agents, with Fe2O3 nanoparticles being explored as potential drug carriers due to their porosity. A nanocomposite of Fe2O3/chitosan/montmorillonite was developed to encapsulate quercetin nanoparticles with less side effects. The designed Fe2O3-CS-MMT@QC showed high drug encapsulation efficiency and controlled release, demonstrating potential for drug delivery to cancer cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Yan Liu, Yongfeng Zhu, Yongsheng Wang, Xicun Wang, Li Zong, Aiqin Wang
Summary: A novel degradable superabsorbent polymer (SAP) was successfully prepared through grafting polymerization, and its properties were systematically studied. The results showed that the SAP exhibited excellent water absorption capabilities and degraded significantly, suggesting its great potential in modern agriculture.
Review
Rheumatology
Yingnan Liu, Yumei Wei, Yueyi Zhang, Huixia Yang
Summary: This meta-analysis aimed to investigate the effect of hydroxychloroquine (HCQ) intervention on the incidence of preeclampsia and other maternal and fetal outcomes in pregnant women with autoimmune disorders. The findings showed that HCQ treatment significantly reduced the risk of preeclampsia and premature delivery, especially in pregnant women with lupus, by lowering the risk of gestational hypertension and preterm birth.
CLINICAL RHEUMATOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Fangfang Yang, Yameng Song, Aiping Hui, Bin Mu, Aiqin Wang
Summary: The rapid development of antibiotic resistance is a major threat to public health. Nanomaterials, particularly ZnO nanocrystal clusters, have shown excellent bactericidal ability. The clusters, formed through a green structure-tuning synthesis process, exhibited superior performance in killing Escherichia coli and Staphylococcus aureus. The antibacterial action is attributed to increased contact with bacteria, the release of small ZnO nanoparticles, and the generation of reactive oxygen species, which damage the bacterial cell membrane. In addition, the attachment of phenolic compounds from olive leaf extract enhances the antibacterial activity of ZnO clusters. This study presents a feasible and clean strategy for improving the structure-bioactivity relationship of ZnO and highlights the potential of ZnO clusters in antibacterial applications due to their excellent performance and green fabrication method.
ACS APPLIED BIO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Teng Zhang, Renyi Li, Xiaoyu Hao, Quanzhen Zhang, Huixia Yang, Yanhui Hou, Baofei Hou, Liangguang Jia, Kaiyue Jiang, Yu Zhang, Xu Wu, Xiaodong Zhuang, Liwei Liu, Yugui Yao, Wei Guo, Yeliang Wang
Summary: Ullmann-like on-surface synthesis is an appropriate approach for fabricating covalent organic nanostructures. In this study, we used 2D hBN as a protective layer and successfully achieved Ullmann-like coupling of a planar biphenylene-based molecule on an hBN/Rh(111) surface. This finding is expected to be important for high-yield fabrication of functional nanostructures for future information devices.
Article
Medicine, General & Internal
Jiahui Chen, Jing Huai, Li Lin, Boya Li, Yuchun Zhu, Huixia Yang
Summary: This study aimed to evaluate the bleeding risk of low-dose aspirin treatment in high-risk pregnant women and the incidence of postpartum hemorrhage (PPH) according to maternal characteristics. The results showed that a dosage of 100 mg aspirin per day did not increase the risk of bleeding or PPH, regardless of maternal characteristics. However, in the aspirin group, there was a significant correlation between BMI and PPH.
CHINESE MEDICAL JOURNAL
(2023)
Article
Ecology
Jun Zhang, Hui-xia Yang, Fan Zhou, Jia-liang Li, Dong-mei Zhou, Guo-zhang Cen, Jing Ma, Xiao-yan Zhu
Summary: The study analyzed the agricultural water footprint (AWF) and its spatiotemporal characteristics in the Hexi corridor, Northwest of China from 2002 to 2017 using the water footprint theory. The AWF increased during the study period, with a rapid increase in the water footprint of cash crops and a slower and stable increase in the water footprint of grain production. There were significant differences in the water footprint of agricultural products among the counties in the Hexi corridor. The study also explored the relationship between AWF and GDP, population, grain yield, fertilization, and urbanization rate, and found that economic growth, grain yield, and fertilization had a significant positive relationship with AWF.
JOURNAL OF ARID ENVIRONMENTS
(2023)
Editorial Material
Microbiology
Yu Liu, Huixia Yang
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Shue Li, Penji Yan, Bin Mu, Yuru Kang, Aiqin Wang
Summary: This study focuses on the preparation, characterization, and multifunctional properties of intelligent hybrid nanopigments. These hybrid nanopigments were fabricated based on natural Monascus red, surfactant, and sepiolite through a simple grinding process. The obtained hybrid nanopigments exhibited excellent antibacterial and antioxidant properties, with enhanced interactions between Monascus red and sepiolite. Furthermore, by combining hybrid nanopigments with fluorinated polysiloxane, gas-sensitive reversible alochroic superamphiphobic coatings were successfully designed with excellent thermal and chemical stability. Therefore, these intelligent multifunctional hybrid nanopigments have great potential applications in related fields.
Article
Green & Sustainable Science & Technology
H. Yu, Y. Zhu, F. Duan, A. Wang
Summary: Researchers have pursued cleanliness and environmental friendliness in the fabrication, adsorption, and regeneration of adsorbent materials. A novel and eco-friendly porous material was successfully fabricated using Pickering aqueous foam, and it was applied for the removal of organic pollutants. The Pickering foam showed excellent stability and was synergistically stabilized by natural nanomaterials attapulgite and gallnut. The adsorbent exhibited excellent adsorption capacities and could be cyclically utilized through carbonization regeneration. This work provides a sustainable and eco-friendly approach, with potential practical applications due to its outstanding adsorption performance and reusability.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Agricultural Engineering
Xinquan Deng, Fangzhi Duan, Yongfeng Zhu, Aiqin Wang, Yian Zheng
Summary: In this study, a highly porous adsorbent was successfully fabricated using a green and stable water-based foam template. The adsorbent, stabilized with agricultural waste quinoa husk, showed high adsorption capacity for dye pollutants in wastewater. A sustainable method for handling the spent adsorbent by converting it into biochar was proposed. Additionally, the biochar was observed to effectively improve soil properties and enhance crop growth.
BIORESOURCE TECHNOLOGY
(2023)
Article
Engineering, Environmental
Fangzhi Duan, Yongfeng Zhu, Hong Zhang, Yushen Lu, Aiqin Wang
Summary: In recent years, attapulgite (APT) has gained wide attention in stabilizing Pickering foam due to its excellent properties. This study investigated the properties of Pickering foam stabilized by APT with structural evolution using oxalic acid and Sapindus mukorossi. The results showed that APT with intact crystal structures had excellent removal rate at low concentration dye, while APT with large crystal defects had advantages in adsorption at high concentration dye. Furthermore, the waste adsorbents were used to prepare soil conditioner, improving the pH, cation exchange capacity, and electrical conductivity of the soil.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Obstetrics & Gynecology
Jie Ning, Jie Yan, Huixia Yang
Summary: This review focuses on the regulatory role of N6-methyladenosine (m6A) in the great obstetrical syndromes and its clinical relevance. The authors discuss the mechanisms of m6A regulation in diseases such as preeclampsia, spontaneous abortion, hyperglycemia in pregnancy, and fetal growth, as well as its relationship with placental function. They summarize the recent research progress and provide a brief perspective on its prospective applications.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Green & Sustainable Science & Technology
Y. Lu, Q. Zhang, B. Mu, A. Wang
Summary: In this study, functional Zn-based mixed metal oxides (Zn-MMOs) were fabricated using a ZnO-assisted hydrothermal coprecipitation method with spent metal ions from acid-leached clay for antibiotic and microorganism removal from water. The results demonstrated that the composition, micro-structure, adsorption, and antibacterial activity of Zn-MMOs were influenced by the amount of ZnO added. Zn-MMOs showed high adsorption capabilities for tetracycline and chlortetracycline, as well as comparable antibacterial activity to commercial ZnO, making them effective for eliminating microbial contaminants in water. This work offers a collaborative solution for waste resource utilization and wastewater pollution treatment, contributing to the promotion of green economy and sustainable development.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Materials Science, Biomaterials
Junli Liu, Jiahao Shen, Yile Wang, Chenfeng Dong, Jin Liu, Yunxiao Yi, Hui Liu, Yan Bao, AiPing Hui, Aiqin Wang
Summary: By modifying polydopamine (PDA) on the surface of molybdenum disulfide (MoS2), small-sized copper nanoparticles were grown uniformly to form MoS2/PDA@Cu nanozyme. This nanozyme exhibited excellent peroxidase-like activity and antibacterial properties, showing a more pronounced inhibitory effect on bacterial growth with the addition of H2O2. The maximum reaction rate (V-max) of the MoS2/PDA@Cu nanozyme is significantly higher than that of horseradish peroxidase (HRP), and it also demonstrated excellent biocompatibility, hemocompatibility, and potential anticancer properties.
BIOMATERIALS SCIENCE
(2023)
Review
Materials Science, Biomaterials
Yinfeng Yang, Xiaomei Wang, Fangfang Yang, Bin Mu, Aiqin Wang
Summary: This review summarizes the hemostatic mechanisms of natural clay minerals based on their nanostructures, reviews the latest research progress for clay minerals-based hemostatic hybrid and nanocomposite materials, and discusses the challenges and developments in this field.
BIOMATERIALS SCIENCE
(2023)
