Saffron: a natural product with potential pharmaceutical applications

Determination of antioxidant activity of saffron taken from the flower of Crocus sativus grown in Lebanon

(2016) Makhlouf Hassane et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

The Effect ofCrocus sativusL. and Its Constituents on Memory: Basic Studies and Clinical Applications

(2015) Nikolaos Pitsikas   Evidence-based Complementary and Alternative Medicine

Safranal, a Crocus sativus L constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. In silico and in vitro study

(2014) George D. Geromichalos et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-tumor activity of safranal against neuroblastoma cells

(2014) JabbariAzad Farahzad et al.   Pharmacognosy Magazine

Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer

(2013) S. Zahra Bathaie et al.   Biochemistry and Cell Biology

Bioactivity assessment and toxicity of crocin: A comprehensive review

(2013) Seyedeh Hoda Alavizadeh et al.   FOOD AND CHEMICAL TOXICOLOGY

Antihyperglycemic and Antioxidant Activity of Crocin in Streptozotocin-Induced Diabetic Rats

(2013) Ziba Rajaei et al.   JOURNAL OF MEDICINAL FOOD

Saffron (Crocus sativus L.) increases glucose uptake and insulin sensitivity in muscle cells via multipathway mechanisms

(2012) Changkeun Kang et al.   FOOD CHEMISTRY

Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study

(2012) Ladan Kashani et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Effects of the active constituents of Crocus Sativus L., crocins, in an animal model of obsessive–compulsive disorder

(2012) G. Georgiadou et al.   NEUROSCIENCE LETTERS

Effect of Crocin on the Insulin Resistance and Lipid Profile of Streptozotocin-Induced Diabetic Rats

(2012) Saeed Shirali et al.   PHYTOTHERAPY RESEARCH

Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial

(2012) Amirhossein Modabbernia et al.   PSYCHOPHARMACOLOGY

Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats

(2011) Saurabh Bharti et al.   EUROPEAN JOURNAL OF NUTRITION

Saffron (Crocus sativus) Aqueous Extract and its Constituent Crocin Reduces Stress-induced Anorexia in Mice

(2011) Bahar-al-Sadat Halataei et al.   PHYTOTHERAPY RESEARCH

Immunomodulatory Effects of Saffron: A Randomized Double-Blind Placebo-Controlled Clinical Trial

(2011) S. Kianbakht et al.   PHYTOTHERAPY RESEARCH

The Effect of Saffron Consumption on Biochemical and Histopathological Heart Indices of Rats with Myocardial Infarction

(2010) Siyavash Joukar et al.   Cardiovascular Toxicology

New Applications and Mechanisms of Action of Saffron and its Important Ingredients

(2010) S. Zahra Bathaie et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Selective Th2 Upregulation byCrocus sativus: A Neutraceutical Spice

(2010) Sarang Bani et al.   Evidence-based Complementary and Alternative Medicine

An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment

(2010) M R Safarinejad et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

ORIGINAL ARTICLE: Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial

(2010) S. Akhondzadeh et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study

(2009) Ila Das et al.   ACTA HISTOCHEMICA

Protective Effect of Saffron Extract and Crocin on Reactive Oxygen Species-Mediated High Glucose-Induced Toxicity in PC12 Cells

(2009) S. H. Mousavi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Further Examination of Antiradical Properties ofCrocus sativusStigmas Extract Rich in Crocins

(2009) Stella A. Ordoudi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.

(2009) Yang Wang et al.   Journal of Natural Medicines

An overview of structural features of DNA and RNA complexes with saffron compounds: Models and antioxidant activity

(2009) C.D. Kanakis et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: A pilot study

(2009) Ali Shamsa et al.   PHYTOMEDICINE

Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats

(2009) S.N. Goyal et al.   PHYTOMEDICINE

Anxiolytic and hypnotic effect ofCrocus sativusaqueous extract and its constituents, crocin and safranal, in mice

(2009) Hossein Hosseinzadeh et al.   PHYTOTHERAPY RESEARCH

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

(2009) Shahin Akhondzadeh et al.   PSYCHOPHARMACOLOGY

Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial

(2008) M Agha-Hosseini et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers

(2008) Mohammad-Hadi Modaghegh et al.   PHYTOMEDICINE

Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety

(2008) N. Pitsikas et al.   PHYTOMEDICINE

The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats

(2007) H. Hosseinzadeh et al.   PHYTOMEDICINE