Pharmacodynamic models of age-structured cell populations

Distributed transit compartments for arbitrary lifespan distributions in aging populations

(2015) Gilbert Koch et al.   JOURNAL OF THEORETICAL BIOLOGY

Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells

(2013) Salaheldin S. Hamed et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Solution and implementation of distributed lifespan models

(2013) Gilbert Koch et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

A semi-mechanistic red blood cell survival model provides some insight into red blood cell destruction mechanisms

(2013) Julia Korell et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model

(2013) Libin Rong et al.   PLoS Computational Biology

Pharmacodynamics-Mediated Drug Disposition (PDMDD) and Precursor Pool Lifespan Model for Single Dose of Romiplostim in Healthy Subjects

(2010) Yow-Ming C. Wang et al.   AAPS Journal

Interpretation of transit compartments pharmacodynamic models as lifespan based indirect response models

(2010) Wojciech Krzyzanski   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Pharmacodynamic Analysis of Recombinant Human Erythropoietin Effect on Reticulocyte Production Rate and Age Distribution in Healthy Subjects

(2009) Juan José Pérez-Ruixo et al.   CLINICAL PHARMACOKINETICS

Flow cytometric analysis of reticulocyte maturation after erythropoietin administration in rats

(2009) Pawel Wiczling et al.   CYTOMETRY PART A

Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients

(2008) Jürgen B. Bulitta et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep

(2008) Kevin J. Freise et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells

(2008) Wojciech Krzyzanski et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS