Interpretation of transit compartments pharmacodynamic models as lifespan based indirect response models

Pharmacodynamics-Mediated Drug Disposition (PDMDD) and Precursor Pool Lifespan Model for Single Dose of Romiplostim in Healthy Subjects

(2010) Yow-Ming C. Wang et al.   AAPS Journal

Population Modeling of Filgrastim PK-PD in Healthy Adults Following Intravenous and Subcutaneous Administrations

(2010) Wojciech Krzyzanski et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacodynamic Analysis of Recombinant Human Erythropoietin Effect on Reticulocyte Production Rate and Age Distribution in Healthy Subjects

(2009) Juan José Pérez-Ruixo et al.   CLINICAL PHARMACOKINETICS

Flow cytometric analysis of reticulocyte maturation after erythropoietin administration in rats

(2009) Pawel Wiczling et al.   CYTOMETRY PART A

Pharmacokinetic and Pharmacodynamic Modeling of Pegylated Thrombopoietin Mimetic Peptide (PEG-TPOm) After Single Intravenous Dose Administration in Healthy Subjects

(2009) Mahesh N. Samtani et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Flow cytometric assessment of homeostatic aging of reticulocytes in rats

(2008) Paweł Wiczling et al.   EXPERIMENTAL HEMATOLOGY

Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep

(2008) Kevin J. Freise et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Pharmacodynamic modeling of the effect of changes in the environment on cellular lifespan and cellular response

(2008) Kevin J. Freise et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells

(2008) Wojciech Krzyzanski et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS