Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates

Impact of ascites volume on clinical outcomes in ovarian cancer: A cohort study

(2017) J. Brian Szender et al.   GYNECOLOGIC ONCOLOGY

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis

(2017) Y Klymenko et al.   ONCOGENE

Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination

(2017) Yuliya Klymenko et al.   NEOPLASIA

Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer

(2017) Yuliya Klymenko et al.   Cancers

Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin

(2016) Alexandra S. Piotrowski-Daspit et al.   Integrative Biology

The mechanical regulation of integrin–cadherin crosstalk organizes cells, signaling and forces

(2016) Keeley L. Mui et al.   JOURNAL OF CELL SCIENCE

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

(2016) Brian D. Cosgrove et al.   NATURE MATERIALS

Stability of the hybrid epithelial/mesenchymal phenotype

(2016) Mohit Kumar Jolly et al.   Oncotarget

Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis

(2015) Mohit Kumar Jolly   Frontiers in Oncology

Compressive Stress Inhibits Proliferation in Tumor Spheroids through a Volume Limitation

(2014) Morgan Delarue et al.   BIOPHYSICAL JOURNAL

Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-LikePhenotype and Activate Wnt/β-Catenin Pathway

(2014) Lilian Gonçalves dos Reis Bastos et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

(2014) Rachel A. Davidowitz et al.   JOURNAL OF CLINICAL INVESTIGATION

Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse

(2013) Triantafyllos Stylianopoulos et al.   CANCER RESEARCH

Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression

(2013) Andrew J. Steward et al.   Journal of the Mechanical Behavior of Biomedical Materials

The epigenetics of epithelial-mesenchymal plasticity in cancer

(2013) Wai Leong Tam et al.   NATURE MEDICINE

Epithelial ovarian cancer experimental models

(2013) E Lengyel et al.   ONCOGENE

Mechanical Stress Impairs Mitosis Progression in Multi-Cellular Tumor Spheroids

(2013) Annaïck Desmaison et al.   PLoS One

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

(2013) K. Alessandri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)

(2013) R Y-J Huang et al.   Cell Death & Disease

Expression of Wnt3 Activates Wnt/ -Catenin Pathway and Promotes EMT-like Phenotype in Trastuzumab-Resistant HER2-Overexpressing Breast Cancer Cells

(2012) Y. Wu et al.   MOLECULAR CANCER RESEARCH

In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis

(2012) Rachel A. Davidowitz et al.   Jove-Journal of Visualized Experiments

TGF-β Blockade Controls Ascites by Preventing Abnormalization of Lymphatic Vessels in Orthotopic Human Ovarian Carcinoma Models

(2011) Shan Liao et al.   CLINICAL CANCER RESEARCH

Mechanical compression drives cancer cells toward invasive phenotype

(2011) J. M. Tse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micro-Environmental Mechanical Stress Controls Tumor Spheroid Size and Morphology by Suppressing Proliferation and Inducing Apoptosis in Cancer Cells

(2009) Gang Cheng et al.   PLoS One

Hydrostatic Pressure Enhances Chondrogenic Differentiation of Human Bone Marrow Stromal Cells in Osteochondrogenic Medium

(2008) Diane R. Wagner et al.   ANNALS OF BIOMEDICAL ENGINEERING

Relapse and survival in early-stage ovarian cancer

(2008) S. Miriam Lenhard et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression

(2008) Laurie G. Hudson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Treatment of Malignant Ascites

(2008) Michael Chung et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis

(2008) Yuanmei Lou et al.   DEVELOPMENTAL DYNAMICS

Intraperitoneal bevacizumab for the palliation of malignant ascites in refractory ovarian cancer

(2008) Chad A. Hamilton et al.   GYNECOLOGIC ONCOLOGY

Tensegrity-based mechanosensing from macro to micro

(2008) Donald E. Ingber   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Molecular mechanisms underlying postoperative peritoneal tumor dissemination may differ between a laparotomy and carbon dioxide pneumoperitoneum: a syngeneic mouse model with controlled respiratory support

(2008) Sachiko Matsuzaki et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Gene Expression Pattern in Biomechanically Stretched Cardiomyocytes

(2007) Derk Frank et al.   HYPERTENSION