Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse

(2013) Javier A. Carrero et al.   PLoS One

A Variable CD3+ T-Cell Frequency in Peripheral Blood Lymphocytes Associated with Type 1 Diabetes Mellitus Development in the LEW.1AR1-iddm Rat

(2013) Tanja Arndt et al.   PLoS One

Etanercept suppresses regenerative hyperplasia in psoriasis by acutely downregulating epidermal expression of interleukin (IL)-19, IL-20 and IL-24

(2012) F. Wang et al.   BRITISH JOURNAL OF DERMATOLOGY

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Anti-TNF Monoclonal Antibodies in Inflammatory Bowel Disease: Pharmacokinetics-Based Dosing Paradigms

(2012) I Ordás et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The problems and promises of research into human immunology and autoimmune disease

(2012) Bart O Roep et al.   NATURE MEDICINE

The Role of TNF-α in Mice with Type 1- and 2- Diabetes

(2012) Maria Koulmanda et al.   PLoS One

What causes type 1 diabetes? Lessons from animal models

(2011) KARSTEN BUSCHARD   APMIS

Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1

(2011) R. Goldbach-Mansky   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differential effects of proinflammatory cytokines on cell death and ER stress in insulin-secreting INS1E cells and the involvement of nitric oxide

(2011) Stella Kacheva et al.   CYTOKINE

Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice

(2011) Eitan M. Akirav et al.   DIABETES

How Does Type 1 Diabetes Develop?: The Notion of Homicide or  -Cell Suicide Revisited

(2011) M. A. Atkinson et al.   DIABETES

Cytokines Tumor Necrosis Factor-α and Interferon-γ Induce Pancreatic β-Cell Apoptosis through STAT1-mediated Bim Protein Activation

(2011) Jenny Barthson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose and aging control the quiescence period that follows pancreatic beta cell replication

(2010) S. J. Salpeter et al.   DEVELOPMENT

 -Cell Growth and Regeneration: Replication Is Only Part of the Story

(2010) S. Bonner-Weir et al.   DIABETES

Diabetes Prevention by Immunomodulatory FTY720 Treatment in the LEW.1AR1-iddmRat Despite Immune Cell Activation

(2010) Anne Jörns et al.   ENDOCRINOLOGY

Enhanced islet expansion by β-cell proliferation in young diabetes-prone rats fed a protective diet

(2010) Gen-Sheng Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Anti-TNFα therapy—killing two birds with one stone?

(2010) Sefina Arif et al.   LANCET

The pancreas in human type 1 diabetes

(2010) Patrick A. Rowe et al.   Seminars in Immunopathology

Immunopathology of the human pancreas in type-I diabetes

(2010) Sarah J. Richardson et al.   Seminars in Immunopathology

Etanercept Treatment in Children With New-Onset Type 1 Diabetes: Pilot randomized, placebo-controlled, double-blind study

(2009) L. Mastrandrea et al.   DIABETES CARE

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

(2009) C. Gysemans et al.   DIABETOLOGIA

Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

(2008) F. Ortis et al.   DIABETOLOGIA