Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic β-cells

(2010) Ismail Syed et al.   BIOCHEMICAL PHARMACOLOGY

Small G Proteins in Islet β-Cell Function

(2010) Anjaneyulu Kowluru   ENDOCRINE REVIEWS

Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

(2009) E N Gurzov et al.   CELL DEATH AND DIFFERENTIATION

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-κB) signalling in human islets and in a mouse beta cell line

(2009) S. A. Sarkar et al.   DIABETOLOGIA

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

(2009) P. Newsholme et al.   DIABETOLOGIA

Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic β-Cells

(2009) D. Morgan et al.   ENDOCRINOLOGY

Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways

(2009) Xiao-Ling Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic β-cells

(2008) Rajakrishnan Veluthakal et al.   BIOCHEMICAL PHARMACOLOGY

NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes?

(2008) Cécile Guichard et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation

(2008) T. Chen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells

(2008) Kleber L A Souza et al.   JOURNAL OF ENDOCRINOLOGY