Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets

C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells

(2012) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

Differential usage of NF-κB activating signals by IL-1β and TNF-α in pancreatic beta cells

(2012) F. Ortis et al.   FEBS LETTERS

A Simple Matter of Life and Death—The Trials of Postnatal Beta-Cell Mass Regulation

(2012) Elena Tarabra et al.   International Journal of Endocrinology

Regulation of pancreatic β-cell survival by nitric oxide

(2012) Francisco J. Bedoya et al.   Islets

Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function

(2011) F. A. Grieco et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Regulation of TNF-induced NF-κB activation by different cytoplasmic ubiquitination events

(2011) Kelly Verhelst et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Genome-Wide RNAi Screens Identify Genes Required for Ricin and PE Intoxications

(2011) Dimitri Moreau et al.   DEVELOPMENTAL CELL

An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells

(2011) A. Beck et al.   DIABETOLOGIA

Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant

(2011) Jonathan S. Rink et al.   SURGERY

A Novel Domain Mediates Insulin-Induced Proteasomal Degradation of Insulin Receptor Substrate 1 (IRS-1)

(2010) Sigalit Boura-Halfon et al.   MOLECULAR ENDOCRINOLOGY

Adhesion of pancreatic beta cells to biopolymer films

(2009) S. Janette Williams et al.   BIOPOLYMERS

Ubiquitin in NF-κB Signaling

(2009) Yu-Hsin Chiu et al.   CHEMICAL REVIEWS

Islet  -Cells Deficient in Bcl-xL Develop but Are Abnormally Sensitive to Apoptotic Stimuli

(2009) E. M. Carrington et al.   DIABETES

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-κB) signalling in human islets and in a mouse beta cell line

(2009) S. A. Sarkar et al.   DIABETOLOGIA

Recent progress in research on beta-cell apoptosis by cytokines

(2009) Kyoung-Ah Kim   Frontiers in Bioscience-Landmark

Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6

(2009) Shu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis and specificity of human otubain 1-mediated deubiquitination

(2008) Mariola J. Edelmann et al.   BIOCHEMICAL JOURNAL

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

(2007) David Komander et al.   BIOCHEMICAL JOURNAL

Transplantation: current developments and future directions; The future of clinical islet transplantation as a cure for diabetes

(2007) Anthony Hogan   Frontiers in Bioscience-Landmark