Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes

Vitamin D in autoimmune, infectious and allergic diseases: A vital player?

(2011) Tom L. Van Belle et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Interleukin-21 Is Critically Required in Autoimmune and Allogeneic Responses to Islet Tissue in Murine Models

(2011) Helen M. McGuire et al.   DIABETES

Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells

(2011) C. Penaranda et al.   JOURNAL OF IMMUNOLOGY

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

(2011) Nicole Sherry et al.   LANCET

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice

(2010) Devangi S. Mehta et al.   IMMUNOLOGY

Genetics, pathogenesis and clinical interventions in type 1 diabetes

(2010) Jeffrey A. Bluestone et al.   NATURE

Immune therapy for type 1 diabetes mellitus—what is unique about anti-CD3 antibodies?

(2010) Lucienne Chatenoud   Nature Reviews Endocrinology

Low-dose cyclosporine A therapy increases the regulatory T cell population in patients with atopic dermatitis

(2009) C. Brandt et al.   ALLERGY

Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients

(2009) B. Keymeulen et al.   BLOOD

Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

(2009) A. P.R. Sutherland et al.   DIABETES

Expansion of Antigen-Specific Regulatory T Cells with the Topical Vitamin D Analog Calcipotriol

(2009) Mehran Ghoreishi et al.   JOURNAL OF IMMUNOLOGY