cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets
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Title
cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets
Authors
Keywords
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Journal
DIABETOLOGIA
Volume 55, Issue 1, Pages 166-174
Publisher
Springer Nature
Online
2011-10-25
DOI
10.1007/s00125-011-2338-7
References
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Related references
Note: Only part of the references are listed.- β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition
- (2011) Catherine A. Jurgens et al. AMERICAN JOURNAL OF PATHOLOGY
- Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
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- Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3
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- Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin
- (2010) Xiao-Ling Li et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status
- (2010) Ilir Mehmeti et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- Beta cell apoptosis in diabetes
- (2009) Helen E. Thomas et al. APOPTOSIS
- Bad News for -Cell Apoptosis
- (2009) H. E. Thomas et al. DIABETES
- Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax
- (2009) M. D. McKenzie et al. DIABETES
- Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-κB) signalling in human islets and in a mouse beta cell line
- (2009) S. A. Sarkar et al. DIABETOLOGIA
- Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress
- (2009) R. L. Hull et al. DIABETOLOGIA
- JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis
- (2009) S. Abdelli et al. DIABETOLOGIA
- Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
- (2009) S. Zraika et al. DIABETOLOGIA
- Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways
- (2009) Xiao-Ling Li et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Islet Graft Response to Transplantation Injury Includes Upregulation of Protective as Well as Apoptotic Genes
- (2008) Silvia Rodríguez-Mulero et al. CELL TRANSPLANTATION
- Glucose and leptin induce apoptosis in human β-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases
- (2008) Kathrin Maedler et al. FASEB JOURNAL
- Initiation and execution of lipotoxic ER stress in pancreatic -cells
- (2008) D. A. Cunha et al. JOURNAL OF CELL SCIENCE
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