Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis

The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease

(2014) Mark A Feitelson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cell cycle-related kinase mediates viral-host signalling to promote hepatitis B virus-associated hepatocarcinogenesis

(2014) Zhuo Yu et al.   GUT

HBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma

(2013) L-p Liu et al.   BRITISH JOURNAL OF CANCER

The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinoma

(2013) Xiaojun Li et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus X Protein-Induced Aberrant Epigenetic Modifications Contributing to Human Hepatocellular Carcinoma Pathogenesis

(2013) Y. Tian et al.   MOLECULAR AND CELLULAR BIOLOGY

Role and Functional Domain of Hepatitis B Virus X Protein in Regulating HBV Transcription and Replication in Vitro and in Vivo

(2013) Dao-Yin Gong et al.   Viruses-Basel

C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by c-jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma

(2012) Karen M.F. Sze et al.   HEPATOLOGY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cell cycle–related kinase is a direct androgen receptor–regulated gene that drives β-catenin/T cell factor–dependent hepatocarcinogenesis

(2011) Hai Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Carboxyl-Terminal Truncated HBx Regulates a Distinct MicroRNA Transcription Program in Hepatocellular Carcinoma Development

(2011) Wing-Kit Yip et al.   PLoS One

The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

(2010) D. Sir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53-Dependent Translational Control of Senescence and Transformation via 4E-BPs

(2009) Emmanuel Petroulakis et al.   CANCER CELL

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Deregulated Direct Targets of the Hepatitis B Virus (HBV) Protein, HBx, Identified through Chromatin Immunoprecipitation and Expression Microarray Profiling

(2009) Wing-Kin Sung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis

(2009) Yasunobu Matsuda et al.   Medical Molecular Morphology

COX-2 mediates hepatitis B virus X protein abrogation of p53-induced apoptosis

(2008) Alfred S.L. Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

COOH-Terminal Truncated HBV X Protein Plays Key Role in Hepatocarcinogenesis

(2008) N.-F. Ma et al.   CLINICAL CANCER RESEARCH

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS