The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease

Hepatocystin/80K-H inhibits replication of hepatitis B virus through interaction with HBx protein in hepatoma cell

(2013) Gu-Choul Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hepatitis B virus inhibits liver regeneration via epigenetic regulation of urokinase-type plasminogen activator

(2013) Eun-Sook Park et al.   HEPATOLOGY

Methyltransferase PRMT1 Is a Binding Partner of HBx and a Negative Regulator of Hepatitis B Virus Transcription

(2013) S. Benhenda et al.   JOURNAL OF VIROLOGY

Hepatitis B Virus X Protein-Induced Aberrant Epigenetic Modifications Contributing to Human Hepatocellular Carcinoma Pathogenesis

(2013) Y. Tian et al.   MOLECULAR AND CELLULAR BIOLOGY

HBx-mediated miR-21 upregulation represses tumor-suppressor function of PDCD4 in hepatocellular carcinoma

(2013) X Qiu et al.   ONCOGENE

Hepatitis B virus (HBV) induces the expression of interleukin-8 that in turn reduces HBV sensitivity to interferon-alpha

(2013) Teresa Pollicino et al.   VIROLOGY

Role and Functional Domain of Hepatitis B Virus X Protein in Regulating HBV Transcription and Replication in Vitro and in Vivo

(2013) Dao-Yin Gong et al.   Viruses-Basel

Hedgehog Signaling Blockade Delays Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein

(2012) A. Arzumanyan et al.   CANCER RESEARCH

Hepatitis B virus X protein modulates oncogene yes-associated protein by CREB to promote growth of hepatoma cells

(2012) Tao Zhang et al.   HEPATOLOGY

C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by c-jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma

(2012) Karen M.F. Sze et al.   HEPATOLOGY

Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinoma

(2012) Limin Xia et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus Encoded X Protein Suppresses Apoptosis by Inhibition of the Caspase-Independent Pathway

(2012) Haiying Liu et al.   JOURNAL OF PROTEOME RESEARCH

Hepatitis B Virus X Protein Drives Multiple Cross-Talk Cascade Loops Involving NF-κB, 5-LOX, OPN and Capn4 to Promote Cell Migration

(2012) Xuan Zhang et al.   PLoS One

Role of miR-148a in Hepatitis B Associated Hepatocellular Carcinoma

(2012) Ke Yuan et al.   PLoS One

The role of hepatitis B virus X protein is related to its differential intracellular localization

(2011) J. Ma et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway

(2011) Yi Mao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Does the Hepatitis B Antigen HBx Promote the Appearance of Liver Cancer Stem Cells?

(2011) A. Arzumanyan et al.   CANCER RESEARCH

FoxM1: A Master Regulator of Tumor Metastasis

(2011) P. Raychaudhuri et al.   CANCER RESEARCH

Proinflammatory cytokine TNF-α increases the stability of hepatitis B virus X protein through NF-κB signaling

(2011) Ruchi Shukla et al.   CARCINOGENESIS

Prolyl cis/trans isomerase signalling pathways in cancer

(2011) Martin Theuerkorn et al.   CURRENT OPINION IN PHARMACOLOGY

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

(2011) Julie Lucifora et al.   JOURNAL OF HEPATOLOGY

Upregulation of IL-23 Expression in Patients with Chronic Hepatitis B Is Mediated by the HBx/ERK/NF- B Pathway

(2011) L. Xia et al.   JOURNAL OF IMMUNOLOGY

Interleukin-32 expression induced by hepatitis B virus protein X is mediated through activation of NF-κB

(2011) Xingfei Pan et al.   MOLECULAR IMMUNOLOGY

Upregulated MicroRNA-29a by Hepatitis B Virus X Protein Enhances Hepatoma Cell Migration by Targeting PTEN in Cell Culture Model

(2011) Guangyao Kong et al.   PLoS One

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

(2011) Yih-Cherng Liou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Induction of Cyclooxygenase-2 Expression by Hepatitis B Virus Depends on Demethylation-associated Recruitment of Transcription Factors to the Promoter

(2011) Xin Yue et al.   Virology Journal

Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein

(2011) Junyi Jiang et al.   Protein & Cell

The Role of NF-κB in Hepatitis B Virus X Protein-Mediated Upregulation of VEGF and MMPs

(2010) Li-ping Liu et al.   CANCER INVESTIGATION

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3

(2010) Yu Wang et al.   JOURNAL OF HEPATOLOGY

The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein

(2010) C. Wei et al.   JOURNAL OF IMMUNOLOGY

HBx-Induced Hepatic Steatosis and Apoptosis Are Regulated by TNFR1- and NF-κB-Dependent Pathways

(2010) Ji Yeon Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

(2010) D. Sir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HBx protein induces EMT through c-Src activation in SMMC-7721 hepatoma cell line

(2009) Shi Zhong Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation

(2009) Brigitte Lankat-Buttgereit et al.   BIOLOGY OF THE CELL

Putative roles of hepatitis B x antigen in the pathogenesis of chronic liver disease

(2009) Mark A. Feitelson et al.   CANCER LETTERS

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression

(2009) M.-Y. Cha et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis B virus X protein overcomes the growth-inhibitory potential of retinoic acid by downregulating retinoic acid receptor- 2 expression via DNA methylation

(2009) J. K. Jung et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis B virus X protein induces hypermethylation of p16INK4Apromoter via DNA methyltransferases in the early stage of HBV-associated hepatocarcinogenesis

(2009) Y.-Z. Zhu et al.   JOURNAL OF VIRAL HEPATITIS

Hepatitis B Virus X Protein Modulates Apoptosis in Primary Rat Hepatocytes by Regulating both NF- B and the Mitochondrial Permeability Transition Pore

(2009) A. J. Clippinger et al.   JOURNAL OF VIROLOGY

Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis

(2009) Yasunobu Matsuda et al.   Medical Molecular Morphology

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

(2009) L. Belloni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression

(2008) Hong Tang et al.   HEPATOLOGY

The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells

(2008) Samuel Martín-Vílchez et al.   HEPATOLOGY

Effects of Hepatitis B Virus X Protein (HBx) on Cell-Growth Inhibition in a CCL13-HBx Stable Cell Line

(2008) Chan-Yen Kuo et al.   INTERVIROLOGY

Hepatitis B virus X protein induces apoptosis by enhancing translocation of Bax to mitochondria

(2008) Hye Jin Kim et al.   IUBMB LIFE

Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A

(2008) Da-Li Zheng et al.   JOURNAL OF HEPATOLOGY

Hepatitis B virus X protein upregulates expression of SMYD3 and C-MYC in HepG2 cells

(2008) Lian Yang et al.   MEDICAL ONCOLOGY

Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells

(2008) Y-G Yoo et al.   ONCOGENE