Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection

Inhibition of Interleukin-1  Decreases Aneurysm Formation and Progression in a Novel Model of Thoracic Aortic Aneurysms

(2014) W. F. Johnston et al.   CIRCULATION

Inhibition of Platelet Activation by Clopidogrel Prevents Hypertension-Induced Cardiac Inflammation and Fibrosis

(2013) Li-Xin Jia et al.   CARDIOVASCULAR DRUGS AND THERAPY

Cathepsin S contributes to macrophage migration via degradation of elastic fibre integrity to facilitate vein graft neointimal hyperplasia

(2013) Hong-Tao Shi et al.   CARDIOVASCULAR RESEARCH

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice

(2013) Christina M. O'Neill et al.   ENDOCRINOLOGY

Molecular mechanisms of thoracic aortic dissection

(2013) Darrell Wu et al.   JOURNAL OF SURGICAL RESEARCH

Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects

(2013) Hirotsugu Kurobe et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice

(2012) Yanwen Qin et al.   CARDIOVASCULAR RESEARCH

Neutrophil-Derived Matrix Metalloproteinase 9 Triggers Acute Aortic Dissection

(2012) Tomohiro Kurihara et al.   CIRCULATION

Clopidogrel, a Platelet P2Y12 Receptor Inhibitor, Reduces Vascular Inflammation and Angiotensin II Induced-Abdominal Aortic Aneurysm Progression

(2012) Ou Liu et al.   PLoS One

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques

(2010) Hiroto Tsukano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

What Is the Role of ER Stress in the Heart?

(2010) Masafumi Kitakaze et al.   CIRCULATION RESEARCH

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

(2009) Nicholas J. Leeper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechano-Sensitive Transcriptional Factor Egr-1 Regulates Insulin-Like Growth Factor-1 Receptor Expression and Contributes to Neointima Formation in Vein Grafts

(2009) Xiaoqian Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mouse strain determines the outcome of wound healing after myocardial infarction

(2009) Susanne W.M. van den Borne et al.   CARDIOVASCULAR RESEARCH

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Mice with Disrupted TGFβ Signaling Have Normal Cerebella Development, but Exhibit Facial Dysmorphogenesis and Strain-Dependent Deficits in Their Body Wall

(2009) Yoshiya Asano et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice

(2009) Brian C. Tieu et al.   JOURNAL OF CLINICAL INVESTIGATION

ER stress in cardiovascular disease

(2009) Tetsuo Minamino et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cellular and molecular mechanisms of thoracic aortic aneurysms

(2009) Ismail El-Hamamsy et al.   Nature Reviews Cardiology

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

(2008) Murray C.H. Clarke et al.   CIRCULATION RESEARCH

Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: Focus on cell–matrix signaling

(2007) Alessandro Della Corte et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY