Inhibition of Platelet Activation by Clopidogrel Prevents Hypertension-Induced Cardiac Inflammation and Fibrosis

Interleukin-12p35 Deletion Promotes CD4 T-Cell–Dependent Macrophage Differentiation and Enhances Angiotensin II–Induced Cardiac Fibrosis

(2012) Yulin Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Serum-Glucocorticoid Regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Contributing to Angiotensin II–Induced Inflammation and Cardiac Fibrosis

(2012) Min Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets: active players in the pathogenesis of arthritis and SLE

(2012) Eric Boilard et al.   Nature Reviews Rheumatology

Reciprocal Interaction between Macrophages and T cells Stimulates IFN-γ and MCP-1 Production in Ang II-induced Cardiac Inflammation and Fibrosis

(2012) Ya-lei Han et al.   PLoS One

Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II

(2012) Feifei Ma et al.   PLoS One

Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhances Ang II–Induced Cardiac Inflammation

(2012) Lili Pan et al.   PLoS One

Novel Role of Platelets in Mediating Inflammatory Responses and Ventricular Rupture or Remodeling Following Myocardial Infarction

(2011) Yang Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angiotensin II Infusion–Induced Inflammation, Monocytic Fibroblast Precursor Infiltration, and Cardiac Fibrosis are Pressure Dependent

(2011) Guanming Qi et al.   Cardiovascular Toxicology

Angiotensin II induces inflammation leading to cardiac remodeling

(2011) Lixin Jia   Frontiers in Bioscience-Landmark

Platelet–Leukocyte Interactions in Cardiovascular Disease and Beyond

(2010) Licia Totani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Modulation of Angiotensin II–Mediated Cardiac Remodeling by the MEF2A Target Gene Xirp2

(2010) Sarah A. McCalmon et al.   CIRCULATION RESEARCH

Smad3 Mediates Cardiac Inflammation and Fibrosis in Angiotensin II–Induced Hypertensive Cardiac Remodeling

(2010) Xiao R. Huang et al.   HYPERTENSION

The immunology of fibrosis: innate and adaptive responses

(2010) Georg Wick et al.   TRENDS IN IMMUNOLOGY

Platelets Control Leukocyte Recruitment in a Murine Model of Cutaneous Arthus Reaction

(2009) Toshihide Hara et al.   AMERICAN JOURNAL OF PATHOLOGY

Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways

(2009) Shoken Honsho et al.   CIRCULATION RESEARCH

Targeting the Degradation of Angiotensin II With Recombinant Angiotensin-Converting Enzyme 2

(2009) Jan Wysocki et al.   HYPERTENSION

Interleukin-1 Receptor Type I Signaling Critically Regulates Infarct Healing and Cardiac Remodeling

(2008) Marcin Bujak et al.   AMERICAN JOURNAL OF PATHOLOGY

Association of low-grade inflammation and platelet activation in patients with hypertension with microalbuminuria

(2008) Patrizia Ferroni et al.   CLINICAL SCIENCE

Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension

(2008) B. Klanke et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY