A novel human model of the neurodegenerative disease GM1 gangliosidosis using induced pluripotent stem cells demonstrates inflammasome activation

Inflammasomes in the CNS

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Comparative receptor tyrosine kinase profiling identifies a novel role for AXL in human stem cell pluripotency

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Targeting the unfolded protein response in disease

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Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

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Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency

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Caspase Functions in Cell Death and Disease

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Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

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Inflammasomes in health and disease

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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

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Functional Roles of Gangliosides in Neurodevelopment: An Overview of Recent Advances

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Intracellular sensing of microbes and danger signals by the inflammasomes

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Lysosomal accumulation of Trk protein in brain of GM1-gangliosidosis mouse and its restoration by chemical chaperone

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Somatic coding mutations in human induced pluripotent stem cells

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Copy number variation and selection during reprogramming to pluripotency

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Genetic engineering of human pluripotent cells using TALE nucleases

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

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Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells

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NLR functions beyond pathogen recognition

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Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

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Dampening insulin signaling by an NLRP3 'meta-flammasome'

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hESC derived neuro-epithelial rosettes recapitulate early mammalian neurulation events; an in vitro model

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Changes in Glycosphingolipid Composition During Differentiation of Human Embryonic Stem Cells to Ectodermal or Endodermal Lineages

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The Inflammasomes

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Common and Uncommon Pathogenic Cascades in Lysosomal Storage Diseases

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A role for mitochondria in NLRP3 inflammasome activation

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

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Genome editing with engineered zinc finger nucleases

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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

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Involvement of neuropeptide Y and its Y1 and Y5 receptors in maintaining self-renewal and proliferation of human embryonic stem cells

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GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

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Enhanced autophagy and mitochondrial aberrations in murine GM1-gangliosidosis

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NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production

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GM1 gangliosidosis: Review of clinical, molecular, and therapeutic aspects

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The NALP3 inflammasome is involved in the innate immune response to amyloid-β

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