Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia

(2014) M. J. Kiel et al.   BLOOD

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

(2014) J. Iqbal et al.   BLOOD

Identification of putative pathogenic microRNA and its downstream targets in anaplastic lymphoma kinase–negative anaplastic large cell lymphoma

(2014) Meenakshi Mehrotra et al.   HUMAN PATHOLOGY

miR-155 Activates Cytokine Gene Expression in Th17 Cells by Regulating the DNA-Binding Protein Jarid2 to Relieve Polycomb-Mediated Repression

(2014) Thelma M. Escobar et al.   IMMUNITY

Reliable Quantification of Protein Expression and Cellular Localization in Histological Sections

(2014) Michaela Schlederer et al.   PLoS One

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

(2013) M. Boi et al.   BLOOD

Lead identification of novel and selective TYK2 inhibitors

(2013) Jun Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

STAT3-mediated activation of microRNA cluster 17 92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

(2013) E. Spaccarotella et al.   HAEMATOLOGICA

A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

(2013) S. J. Sohn et al.   JOURNAL OF IMMUNOLOGY

Therapeutic opportunities of the IL-22–IL-22R1 system

(2013) Robert Sabat et al.   NATURE REVIEWS DRUG DISCOVERY

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP

(2013) Jan Meier et al.   RNA Biology

TYK2–STAT1–BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia

(2013) Takaomi Sanda et al.   Cancer Discovery

Extensive Promoter DNA Hypermethylation and Hypomethylation Is Associated with Aberrant MicroRNA Expression in Chronic Lymphocytic Leukemia

(2012) C. Baer et al.   CANCER RESEARCH

PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

(2012) Daniela Laimer et al.   NATURE MEDICINE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

(2011) Stephan Blüml et al.   ARTHRITIS AND RHEUMATISM

Anaplastic large-cell lymphoma

(2011) Giorgio Inghirami et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing

(2010) A. L. Feldman et al.   BLOOD

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma

(2010) O. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-21 Contributes to JAK3/STAT3 Activation and Promotes Cell Growth in ALK-Positive Anaplastic Large Cell Lymphoma

(2009) Jennifer Dien Bard et al.   AMERICAN JOURNAL OF PATHOLOGY

NPM-ALK inhibits the p53 tumor suppressor pathway in an MDM2 and JNK-dependent manner

(2009) Y.-X. Cui et al.   BLOOD

B7-H1 expression is regulated by MEK/ERK signaling pathway in anaplastic large cell lymphoma and Hodgkin lymphoma

(2009) Ryo Yamamoto et al.   CANCER SCIENCE

Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma

(2009) S Eckerle et al.   LEUKEMIA

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project

(2008) K. J. Savage et al.   BLOOD

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma

(2008) J Dien Bard et al.   LEUKEMIA