Glucagon-like peptide-1: modulator ofβ-cell dysfunction and death

Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes

(2012) Z. F. Kang et al.   DIABETOLOGIA

Antiapoptotic Actions of Exendin-4 against Hypoxia and Cytokines Are Augmented by CREB

(2012) Kalpana Velmurugan et al.   ENDOCRINOLOGY

Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion

(2012) Sonya G. Fonseca et al.   NATURE CELL BIOLOGY

In Vitro Proliferation of Adult Human Beta-Cells

(2012) Sabine Rutti et al.   PLoS One

Snapin Mediates Incretin Action and Augments Glucose-Dependent Insulin Secretion

(2011) Woo-Jin Song et al.   Cell Metabolism

The potential of incretin-based therapies in type 1 diabetes

(2011) Chen S. Suen et al.   DRUG DISCOVERY TODAY

Activation of the GLP-1 Receptor Signalling Pathway: A Relevant Strategy to Repair a Deficient Beta-Cell Mass

(2011) Bernard Portha et al.   Experimental Diabetes Research

Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor

(2011) K. Coopman et al.   MOLECULAR ENDOCRINOLOGY

Roles and Regulation of the Transcription Factor CREB in Pancreatic β -Cells

(2011) Stephane Dalle et al.   Current Molecular Pharmacology

Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells

(2009) Jenny Vikman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional β-Cell Mass and Insulin Sensitivity Is Decreased in Insulin-Independent Pancreas-Kidney Recipients

(2009) Pieter Gillard et al.   TRANSPLANTATION

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

(2008) Zhi-Liang Chu et al.   ENDOCRINOLOGY

Role of the cAMP sensor Epac as a determinant of KATPchannel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells

(2008) Guoxin Kang et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

(2008) W. Kim et al.   PHARMACOLOGICAL REVIEWS