Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion

cAMP-secretion coupling is impaired in diabetic GK/Par rat β-cells: a defect counteracted by GLP-1

(2011) Manuel Dolz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic  -cells

(2011) M. Hatanaka et al.   HUMAN MOLECULAR GENETICS

Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells

(2010) B. Roger et al.   DIABETOLOGIA

cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

(2010) Olof Idevall-Hagren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

(2010) Sonya G. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94

(2009) Chihiro Kakiuchi et al.   PLoS One

Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs

(2008) C. Pinto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Synchronizing Ca2+ and cAMP oscillations in pancreatic β-cells: a role for glucose metabolism and GLP-1 receptors?Focus on “Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic β-cell: a computational approach”

(2007) George G. Holz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY