Cell Replacement Strategies Aimed at Reconstitution of the β-Cell Compartment in Type 1 Diabetes

Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering

(2013) Sayed-Hadi Mirmalek-Sani et al.   BIOMATERIALS

Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering

(2013) Saik-Kia Goh et al.   BIOMATERIALS

Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells

(2013) Maria João Lima et al.   DIABETES

Biliary tree stem cells, precursors to pancreatic committed progenitors: Evidence for possible life-long pancreatic organogenesis

(2013) Yunfang Wang et al.   STEM CELLS

Biologic scaffolds composed of central nervous system extracellular matrix

(2012) Peter M. Crapo et al.   BIOMATERIALS

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

(2012) Yong Zhao et al.   BMC Medicine

Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

(2012) Jieun Lee et al.   CELL

Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation

(2012) R Rizzi et al.   CELL DEATH AND DIFFERENTIATION

Cell and organ bioengineering technology as applied to gastrointestinal diseases

(2012) Giuseppe Orlando et al.   GUT

Efficient differentiation of AR42J cells towards insulin-producing cells using pancreatic transcription factors in combination with growth factors

(2012) Maria João Lima et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The biliary tree—a reservoir of multipotent stem cells

(2012) Vincenzo Cardinale et al.   Nature Reviews Gastroenterology & Hepatology

From cellular therapies to tissue reprogramming and regenerative strategies in the treatment of diabetes

(2012) Camillo Ricordi et al.   Regenerative Medicine

Concise Review: Mesenchymal Stem Cells for Diabetes

(2012) Juan Domínguez-Bendala et al.   Stem Cells Translational Medicine

Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

(2011) Ori Bar-Nur et al.   Cell Stem Cell

Towards xenotransplantation of pig islets in the clinic

(2011) Robert B Elliott   Current Opinion in Organ Transplantation

Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases

(2011) G. Basta et al.   DIABETES CARE

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Functional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiation

(2011) Tao Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TGF- i Promotes Islet  -Cell Function and Regeneration

(2011) B. Han et al.   JOURNAL OF IMMUNOLOGY

Somatic coding mutations in human induced pluripotent stem cells

(2011) Athurva Gore et al.   NATURE

Copy number variation and selection during reprogramming to pluripotency

(2011) Samer M. Hussein et al.   NATURE

The dark side of induced pluripotency

(2011) Martin F. Pera   NATURE

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells

(2011) Yuki Ohi et al.   NATURE CELL BIOLOGY

Organ engineering based on decellularized matrix scaffolds

(2011) Jeremy J. Song et al.   TRENDS IN MOLECULAR MEDICINE

Bone marrow-derived mesenchymal stem cells for treatment of heart failure: is it all paracrine actions and immunomodulation?

(2010) Pankaj Kumar Mishra   Journal of Cardiovascular Medicine

Bio-engineered endocrine pancreas based on decellularized pancreatic matrix and mesenchymal stem cell/islet cell coculture

(2010) Claudius Conrad et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence

(2010) Qiang Feng et al.   STEM CELLS

Memory in Induced Pluripotent Stem Cells: Reprogrammed Human Retinal-Pigmented Epithelial Cells Show Tendency for Spontaneous Redifferentiation

(2010) Qirui Hu et al.   STEM CELLS

Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression

(2010) Denis Dufrane et al.   TRANSPLANTATION

Cellular plasticity of the pancreas

(2009) Luc Baeyens et al.   BIOLOGICAL CHEMISTRY

Bioengineering of a functional sheet of islet cells for the treatment of diabetes mellitus

(2009) Hirofumi Shimizu et al.   BIOMATERIALS

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

(2009) Jie Deng et al.   NATURE BIOTECHNOLOGY

Mesenchymal Stem Cells Derived From Human Exocrine Pancreas Express Transcription Factors Implicated in Beta-Cell Development

(2009) Reto M. Baertschiger et al.   PANCREAS

Mesenchymal Stem Cells Adopt β-Cell Fate Upon Diabetic Pancreatic Microenvironment

(2009) Caihong Chang et al.   PANCREAS

Induced pluripotent stem cells: an emerging technology platform and the Gartner hype cycle

(2009) Chris Mason et al.   Regenerative Medicine

In Vivo Selection of Biocompatible Alginates for Islet Encapsulation and Subcutaneous Transplantation

(2009) Sophie Vériter et al.   TISSUE ENGINEERING PART A

Autologous stem cell transplantation for early type 1 diabetes mellitus

(2008) Carlos Eduardo Barra Couri et al.   AUTOIMMUNITY

Systemic Administration of Multipotent Mesenchymal Stromal Cells Reverts Hyperglycemia and Prevents Nephropathy in Type 1 Diabetic Mice

(2008) Fernando E. Ezquer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes

(2008) R. Abdi et al.   DIABETES

A Simple Method to Induce Differentiation of Murine Bone Marrow Mesenchymal Cells to Insulin-producing Cells Using Conophylline and Betacellulin-delta4

(2008) Etsuko HISANAGA et al.   ENDOCRINE JOURNAL

Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts

(2008) Keisuke Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decision time for pancreatic islet-cell transplantation

(2008) Piero Ruggenenti et al.   LANCET

Mesenchymal stem cell therapy for diabetes through paracrine mechanisms

(2008) Yu-Xin Xu et al.   MEDICAL HYPOTHESES

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

Cell–Matrix Interactions Improve β-Cell Survival and Insulin Secretion in Three-Dimensional Culture

(2008) Laney M. Weber et al.   TISSUE ENGINEERING PART A

Fibronectin and pellet suspension culture promote differentiation of human mesenchymal stem cells into insulin producing cells

(2007) Ching-Fang Chang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A