From cellular therapies to tissue reprogramming and regenerative strategies in the treatment of diabetes

Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

(2012) A. Rezania et al.   DIABETES

Regeneration of pancreatic beta-cell mass for the treatment of diabetes

(2012) Juan Domínguez-Bendala et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

(2011) Ori Bar-Nur et al.   Cell Stem Cell

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Somatic coding mutations in human induced pluripotent stem cells

(2011) Athurva Gore et al.   NATURE

Copy number variation and selection during reprogramming to pluripotency

(2011) Samer M. Hussein et al.   NATURE

The dark side of induced pluripotency

(2011) Martin F. Pera   NATURE

Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells

(2011) Yuya Kunisada et al.   Stem Cell Research

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Bone marrow-derived mesenchymal stem cells for treatment of heart failure: is it all paracrine actions and immunomodulation?

(2010) Pankaj Kumar Mishra   Journal of Cardiovascular Medicine

Phenotypic differences during the osteogenic differentiation of single cell-derived clones isolated from human lipoaspirates

(2010) Beatriz Paredes et al.   Journal of Tissue Engineering and Regenerative Medicine

A nonviral minicircle vector for deriving human iPS cells

(2010) Fangjun Jia et al.   NATURE METHODS

Stem cell therapy for type 1 diabetes mellitus

(2010) Cristina Aguayo-Mazzucato et al.   Nature Reviews Endocrinology

Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence

(2010) Qiang Feng et al.   STEM CELLS

New perspectives in human stem cell therapeutic research

(2009) Alan Trounson   BMC Medicine

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

How to make β cells?

(2009) Malgorzata Borowiak et al.   CURRENT OPINION IN CELL BIOLOGY

Stem Cells to Pancreatic β-Cells: New Sources for Diabetes Cell Therapy

(2009) Tingxia Guo et al.   ENDOCRINE REVIEWS

Stem cells as a therapeutic target for diabetes

(2009) Paras Kumar Mishra   Frontiers in Bioscience-Landmark

Insulin-producing cells derived from stem/progenitor cells: therapeutic implications for diabetes mellitus

(2009) Yuichi Hori   Medical Molecular Morphology

Reprogramming into pancreatic endocrine cells based on developmental cues

(2009) Simon Kordowich et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A small molecule that directs differentiation of human ESCs into the pancreatic lineage

(2009) Shuibing Chen et al.   Nature Chemical Biology

Induced pluripotent stem cells and reprogramming: seeing the science through the hype

(2009) Juan Carlos Izpisúa Belmonte et al.   NATURE REVIEWS GENETICS

Mesenchymal Stem Cells Derived From Human Exocrine Pancreas Express Transcription Factors Implicated in Beta-Cell Development

(2009) Reto M. Baertschiger et al.   PANCREAS

Autoimmune Pancreatitis Associated With High Prevalence of Gastric Ulcer Independent of Helicobacter pylori Infection Status

(2009) Ming-Chu Chang et al.   PANCREAS

Induced pluripotent stem cells: an emerging technology platform and the Gartner hype cycle

(2009) Chris Mason et al.   Regenerative Medicine

Plasticity of stem cells derived from adult periodontal ligament

(2009) C-Y Charles Huang et al.   Regenerative Medicine

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Challenges in Umbilical Cord Blood Stem Cell Banking for Stem Cell Reviews and Reports

(2009) Karen Ballen   Stem Cell Reviews and Reports

Private Cord Blood Banking: Current Use and Clinical Future

(2009) Peter Hollands et al.   Stem Cell Reviews and Reports

Generation of Pancreatic Hormone-Expressing Islet-Like Cell Aggregates from Murine Adipose Tissue-Derived Stem Cells

(2009) Vikash Chandra et al.   STEM CELLS

Insulin-Secreting Cells from Human Eyelid-Derived Stem Cells Alleviate Type I Diabetes in Immunocompetent Mice

(2009) Hyun Mi Kang et al.   STEM CELLS

Prolonged Insulin Independence After Islet Allotransplants in Recipients with Type 1 Diabetes

(2008) M. D. Bellin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Systemic Administration of Multipotent Mesenchymal Stromal Cells Reverts Hyperglycemia and Prevents Nephropathy in Type 1 Diabetic Mice

(2008) Fernando E. Ezquer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

(2008) Yan Shi et al.   Cell Stem Cell

Mesenchymal stroma cells improve hyperglycemia and insulin deficiency in the diabetic porcine pancreatic microenvironment

(2008) C. Chang et al.   CYTOTHERAPY

Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes

(2008) R. Abdi et al.   DIABETES

A Simple Method to Induce Differentiation of Murine Bone Marrow Mesenchymal Cells to Insulin-producing Cells Using Conophylline and Betacellulin-delta4

(2008) Etsuko HISANAGA et al.   ENDOCRINE JOURNAL

Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts

(2008) Keisuke Tateishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Fibronectin and pellet suspension culture promote differentiation of human mesenchymal stem cells into insulin producing cells

(2007) Ching-Fang Chang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A