The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

The role of aging upon β cell turnover

(2013) Jake A. Kushner   JOURNAL OF CLINICAL INVESTIGATION

The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis

(2012) Martine Vaxillaire et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells

(2012) Xin Cheng et al.   Cell Stem Cell

Monogenic Models: What Have the Single Gene Disorders Taught Us?

(2012) Tomasz Klupa et al.   Current Diabetes Reports

Munc18-1 Regulates First-phase Insulin Release by Promoting Granule Docking to Multiple Syntaxin Isoforms

(2012) Eunjin Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

(2012) Shouhong Xuan et al.   JOURNAL OF CLINICAL INVESTIGATION

GATA4 and GATA6 control mouse pancreas organogenesis

(2012) Manuel Carrasco et al.   JOURNAL OF CLINICAL INVESTIGATION

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Mechanisms of Control of the Free Ca2+ Concentration in the Endoplasmic Reticulum of Mouse Pancreatic  -Cells: Interplay With Cell Metabolism and [Ca2+]c and Role of SERCA2b and SERCA3

(2011) M. A. Ravier et al.   DIABETES

Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets

(2011) C. Dai et al.   DIABETOLOGIA

Loss of Granuphilin and Loss of Syntaxin-1A Cause Differential Effects on Insulin Granule Docking and Fusion

(2011) Hao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MafA and MafB activity in pancreatic β cells

(2011) Yan Hang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

(2010) C. Aguayo-Mazzucato et al.   DIABETOLOGIA

Phosphorylation within the MafA N Terminus Regulates C-terminal Dimerization and DNA Binding

(2010) Shuangli Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Islet  -Cell-Specific MafA Transcription Requires the 5'-Flanking Conserved Region 3 Control Domain

(2010) J. C. Raum et al.   MOLECULAR AND CELLULAR BIOLOGY

Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion

(2009) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

(2009) Jennifer M. Oliver-Krasinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

On the origin of the   cell

(2008) J. M. Oliver-Krasinski et al.   GENES & DEVELOPMENT

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

MafA is a dedicated activator of the insulin gene in vivo

(2008) Isabella Artner et al.   JOURNAL OF ENDOCRINOLOGY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

A Polymorphism Within the G6PC2 Gene Is Associated with Fasting Plasma Glucose Levels

(2008) N. Bouatia-Naji et al.   SCIENCE