4.2 Review

Fifty years of allergy: 1965-2015

Journal

JOURNAL OF PAEDIATRICS AND CHILD HEALTH
Volume 51, Issue 1, Pages 91-93

Publisher

WILEY
DOI: 10.1111/jpc.12806

Keywords

advances; allergy; future; history

Categories

Ask authors/readers for more resources

The last 50 years in allergy could almost be considered the first 50 years. Over this time period, we have witnessed the emergence of allergy as a subspecialty, have seen and continue to observe a tremendous change in prevalence of allergic disease and have gained insight into the mechanisms that underlie allergic predisposition and disease manifestation. We have improved the care of children with many forms of allergic disease and now sit poised to be able to alter the natural history of allergic disease with the use of specific immunotherapy. There is much left to do in the next 50 years including understanding what underlies both the predisposition to atopic disease and its natural resolution and identifying the environmental cofactors involved in the allergic epidemic' and therefore targets for effective primary prevention.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Allergy

Added Diagnostic Value of Peanut Component Testing: A Cross-Sectional Study in Australian Children

Narinder Kaur, Sam Mehr, Constance Katelaris, Brynn Wainstein, Betina Altavilla, Rebecca Saad, Carolina Valerio, Miriam Codarini, Pamela Burton, Fiona Perram, Karl Baumgart, Elizabeth H. Barnes, Dianne E. Campbell

Summary: This study found that sensitization to a combination of Ara h 1, 2, and 3 was highly predictive of peanut allergy. Among individual components, only Ara h 2 was most correlated with severity of reaction at challenge and adrenaline use. Ara h 8 and 9 were not useful in predicting challenge outcome.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Article Allergy

An exploration of factors associated with food protein-induced enterocolitis syndrome: Birth, infant feeding and food triggers

Eric Lee, Elizabeth H. Barnes, Sam Mehr, Dianne E. Campbell

Summary: In this retrospective cohort study on children with acute FPIES in Australia, rice, cow's milk, and soya were identified as the most common triggers. Vaginal delivery may have a protective effect against the development of multiple FPIES and severe reactions. Patients with fish-induced FPIES took longer to outgrow their reactions compared to those with rice or grains-induced FPIES.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2021)

Article Allergy

Using data from food challenges to inform management of consumers with food allergy: A systematic review with individual participant data meta-analysis

Nandinee Patel, Daniel C. Adelman, Katherine Anagnostou, Joseph L. Baumert, W. Marty Blom, Dianne E. Campbell, R. Sharon Chinthrajah, E. N. Clare Mills, Bushra Javed, Natasha Purington, Benjamin C. Remington, Hugh A. Sampson, Alexander D. Smith, Ross A. R. Yarham, Paul J. Turner

Summary: The study found that 5% of individuals with peanut allergy may develop anaphylaxis in response to exposure at ED01 or ED05 levels of peanut. Additionally, 2.4% of patients initially tolerating 5 mg of peanut protein developed reactions at subsequent challenge.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Article Allergy

COVID-19 vaccine-associated anaphylaxis: A statement of the World Allergy Organization Anaphylaxis Committee

Paul J. Turner, Ignacio J. Ansotegui, Dianne E. Campbell, Victoria Cardona, Motohiro Ebisawa, Yehia El-Gamal, Stanley Fineman, Mario Geller, Alexei Gonzalez-Estrada, Paul A. Greenberger, Agnes S. Y. Leung, Michael E. Levin, Antonella Muraro, Mario Sanchez Borges, Gianenrico Senna, Luciana K. Tanno, Bernard Yu-Hor Thong, Margitta Worm

Summary: Vaccines against COVID-19 are crucial for controlling the pandemic, with most adverse events being a result of immune response rather than allergic reactions. Although anaphylaxis is rare with vaccines, recent data on reactions to the Pfizer-BioNTech vaccine suggest a closer incidence rate of 1 in 200,000 doses. A global surveillance strategy led by allergists is proposed to gather data and provide evidence-based guidance to public health bodies and the public for reassurance.

WORLD ALLERGY ORGANIZATION JOURNAL (2021)

Article Nutrition & Dietetics

The Milk Metabolome of Non-secretor and Lewis Negative Mothers

Aidong Wang, Petya Koleva, Elloise du Toit, Donna T. Geddes, Daniel Munblit, Susan L. Prescott, Merete Eggesbo, Christine C. Johnson, Ganesa Wegienka, Naoki Shimojo, Dianne Campbell, Anita L. Kozyrskyj, Carolyn M. Slupsky

Summary: This research report highlights the differences in milk metabolome between Se-Le- mothers and other HMO phenotypes, showing major variances in free fatty acids, free amino acids, and metabolites related to energy metabolism in the Se-Le- milk samples.

FRONTIERS IN NUTRITION (2021)

Letter Allergy

Predicted number of peanut-allergic patients needed to treat with epicutaneous immunotherapy (EPIT) to prevent one allergic reaction: A novel approach to assessing relevance

Benjamin C. Remington, Stef J. Koppelman, Todd D. Green, Gideon Lack, Graham Roberts, Dianne E. Campbell

ALLERGY (2021)

Letter Allergy

Reduction in peanut reaction severity during oral challenge after 12 months of epicutaneous immunotherapy

Philippe Begin, John Andrew Bird, Jonathan M. Spergel, Dianne E. Campbell, Todd D. Green, Katharine J. Bee, Romain Lambert, Hugh A. Sampson, David M. Fleischer

ALLERGY (2021)

Letter Allergy

Impact of COVID-19 pandemic on quality of life for children and adolescents with food allergy

Gang Chen, Audrey DunnGalvin, Dianne E. Campbell

CLINICAL AND EXPERIMENTAL ALLERGY (2022)

Article Allergy

Anaphylaxis knowledge gaps and future research priorities: A consensus report

Timothy E. Dribin, David Schnadower, Julie Wang, Carlos A. Camargo, Kenneth A. Michelson, Marcus Shaker, Susan A. Rudders, David Vyles, David B. K. Golden, Jonathan M. Spergel, Ronna L. Campbell, Mark Neuman, Peter S. Capucilli, Michael Pistiner, Mariana Castells, Juhee Lee, David C. Brousseau, Lynda C. Schneider, Amal H. Assa'ad, Kimberly A. Risma, Rakesh D. Mistry, Dianne E. Campbell, Margitta Worm, Paul J. Turner, John K. Witry, Yin Zhang, Brad Sobolewski, Hugh A. Sampson

Summary: This study systematically identifies and evaluates knowledge gaps and future research priorities in the field of anaphylaxis. It emphasizes the importance of harmonizing scientific pursuits to optimize outcomes for patients with and at risk of anaphylaxis.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Article Pediatrics

Anaphylaxis to foods purchased from food establishments in Australia

Giovanni A. Zurzolo, Dianne E. Campbell, Maria Said, Rachel L. Peters, Shyamali C. Dharmage

Summary: Despite a high proportion of individuals declaring their food allergy to staff, anaphylaxis from food purchased at food establishments is not uncommon. Consumers with food allergy would like to see allergen information listed on menus and for staff to proactively inquire about food allergies. A regularly updated food allergen matrix is required to provide easy access to information on menu items and common allergens for both staff and consumers.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH (2022)

Article Allergy

Deriving health utility indices from a food allergy quality-of-life questionnaire

Gang Chen, Audrey DunnGalvin, Matthew Greenhawt, Marcus Shaker, Dianne E. Campbell

Summary: This study aimed to develop mapping algorithms from the FAQLQ-PF onto HSU scores generated by generic, preference-based, health-related quality-of-life instruments. Results showed mean FAQLQ-PF total score, AQoL-6D, and CHU9D utility scores, with optimal mapping algorithms generated from selected FAQLQ-PF items and AQoL-6D demonstrating better performance.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2021)

Article Allergy

Peanut Can Be Used as a Reference Allergen for Hazard Characterization in Food Allergen Risk Management: A Rapid Evidence Assessment and Meta-Analysis

Paul J. Turner, Nandinee Patel, Barbara K. Ballmer-Weber, Joe L. Baumert, W. Marty Blom, Simon Brooke-Taylor, Helen Brough, Dianne E. Campbell, Hongbing Chen, R. Sharon Chinthrajah, Rene W. R. Crevel, Anthony E. J. Dubois, Motohiro Ebisawa, Arnon Elizur, Jennifer D. Gerdts, M. Hazel Gowland, Geert F. Houben, Jonathan O. B. Hourihane, Andre C. Knulst, Sebastien La Vieille, Maria Cristina Lopez, E. N. Clare Mills, Gustavo A. Polenta, Natasha Purington, Maria Said, Hugh A. Sampson, Sabine Schnadt, Eva Sodergren, Stephen L. Taylor, Benjamin C. Remington

Summary: Regional and national legislation require the disclosure of priority allergens in foods, but unintentional allergen presence is not regulated. Precautionary allergen labels (PAL) are frequently ignored by food-allergic consumers. Establishing internationally agreed reference doses and conducting hazard characterization at low-level allergen exposure can aid in better allergen risk management and the use of PAL.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2022)

Editorial Material Pediatrics

Food protein enterocolitis syndrome: underdiagnosed, not treated optimally

Dianne E. Campbell, Paul J. Turner

ARCHIVES OF DISEASE IN CHILDHOOD (2022)

Article Immunology

Hyper-IgE Syndrome due to an Elusive Novel Intronic Homozygous Variant in DOCK8

Stuart G. Tangye, Paul E. Gray, Bethany A. Pillay, Jin Yan Yap, William A. Figgett, John Reeves, Sarah K. Kummerfeld, Jennifer Stoddard, Gulbu Uzel, Huie Jing, Helen C. Su, Dianne E. Campbell, Anna Sullivan, Leslie Burnett, Jane Peake, Cindy S. Ma

Summary: Rare biallelic loss-of-function mutations in the DOCK8 gene can lead to severe immune deficiency with symptoms such as recurrent cutaneous infections, eczema, allergies, and susceptibility to malignancy. Next-generation sequencing technologies enable rapid molecular diagnosis of rare monogenic diseases, facilitating the implementation of gene-guided treatments.

JOURNAL OF CLINICAL IMMUNOLOGY (2022)

Article Allergy

Commercial shellfish skin prick test extracts show critical variability in allergen repertoire

Thimo Ruethers, Elecia B. Johnston, Shaymaviswanathan Karnaneedi, Shuai Nie, Roni Nugraha, Aya C. Taki, Sandip D. Kamath, Nicholas A. Williamson, Sam S. Mehr, Dianne E. Campbell, Andreas L. Lopata

ALLERGY (2023)

No Data Available