Modeling of Autism Genetic Variations in Mice: Focusing on Synaptic and Microcircuit Dysfunctions

RETRACTED: Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism

(2011) M Ali Bangash et al.   CELL

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Risk factors for autism: translating genomic discoveries into diagnostics

(2011) Stephen W. Scherer et al.   HUMAN GENETICS

Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes

(2011) Swarkar Sharma et al.   HUMAN MOLECULAR GENETICS

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Targeted treatments for fragile X syndrome

(2011) Elizabeth Berry-Kravis et al.   Journal of Neurodevelopmental Disorders

A new synaptic player leading to autism risk: Met receptor tyrosine kinase

(2011) Matthew C. Judson et al.   Journal of Neurodevelopmental Disorders

Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase

(2011) S. Qiu et al.   JOURNAL OF NEUROSCIENCE

Regulation of MET by FOXP2, Genes Implicated in Higher Cognitive Dysfunction and Autism Risk

(2011) Z. Mukamel et al.   JOURNAL OF NEUROSCIENCE

Altered Neocortical Rhythmic Activity States in Fmr1 KO Mice Are Due to Enhanced mGluR5 Signaling and Involve Changes in Excitatory Circuitry

(2011) S. A. Hays et al.   JOURNAL OF NEUROSCIENCE

SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism

(2011) C M Durand et al.   MOLECULAR PSYCHIATRY

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

(2011) Sébastien Jacquemont et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

The conundrums of understanding genetic risks for autism spectrum disorders

(2011) Matthew W State et al.   NATURE NEUROSCIENCE

Gene expression studies in autism: Moving from the genome to the transcriptome and beyond

(2011) Irina Voineagu   NEUROBIOLOGY OF DISEASE

Solving the Autism Puzzle a Few Pieces at a Time

(2011) Christian P. Schaaf et al.   NEURON

SnapShot: Genetics of Autism

(2011) Kimberly A. Aldinger et al.   NEURON

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism

(2011) G. Horev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

The autism risk genes MET and PLAUR differentially impact cortical development

(2010) Kathie L. Eagleson et al.   Autism Research

A Common Genetic Variant in the Neurexin Superfamily Member CNTNAP2 Is Associated with Increased Risk for Selective Mutism and Social Anxiety-Related Traits

(2010) Murray B. Stein et al.   BIOLOGICAL PSYCHIATRY

Conserved Subcortical and Divergent Cortical Expression of Proteins Encoded by Orthologs of the Autism Risk Gene MET

(2010) Matthew C. Judson et al.   CEREBRAL CORTEX

Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain

(2010) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

(2010) J. L. Olmos-Serrano et al.   JOURNAL OF NEUROSCIENCE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits

(2010) Megan E. Williams et al.   NEURON

The Genetics of Child Psychiatric Disorders: Focus on Autism and Tourette Syndrome

(2010) Matthew W. State   NEURON

The Clinical-Basic Interface in Defining Pathogenesis in Disorders of Neurodevelopmental Origin

(2010) Barbara L. Thompson et al.   NEURON

The Challenge of Translation in Social Neuroscience: A Review of Oxytocin, Vasopressin, and Affiliative Behavior

(2010) Thomas R. Insel   NEURON

Neurexins Physically and Functionally Interact with GABAA Receptors

(2010) Chen Zhang et al.   NEURON

Further evidence for the role of MET in autism susceptibility

(2010) Ismail Thanseem et al.   NEUROSCIENCE RESEARCH

Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2

(2010) A. A. Scott-Van Zeeland et al.   Science Translational Medicine

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

(2010) Roberto Toro et al.   TRENDS IN GENETICS

Further evidence that the rs1858830 C variant in the promoter region of theMETgene is associated with autistic disorder

(2009) Pamela B. Jackson et al.   Autism Research

Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome

(2009) Regina Dahlhaus et al.   BEHAVIOURAL BRAIN RESEARCH

A Topographic Study of Minicolumnar Core Width by Lamina Comparison between Autistic Subjects and Controls: Possible Minicolumnar Disruption due to an Anatomical Element In-Common to Multiple Laminae

(2009) Manuel F. Casanova et al.   BRAIN PATHOLOGY

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

The Postsynaptic Density Proteins Homer and Shank Form a Polymeric Network Structure

(2009) Mariko Kato Hayashi et al.   CELL

Extending the phenotype of recurrent rearrangements of 16p11.2: Deletions in mentally retarded patients without autism and in normal individuals

(2009) E.K. Bijlsma et al.   European Journal of Medical Genetics

The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders

(2009) Pat Levitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain

(2009) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Synaptic Circuit Abnormalities of Motor-Frontal Layer 2/3 Pyramidal Neurons in an RNA Interference Model of Methyl-CpG-Binding Protein 2 Deficiency

(2009) L. Wood et al.   JOURNAL OF NEUROSCIENCE

Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

(2009) Joseph T. Glessner et al.   NATURE

Microduplications of 16p11.2 are associated with schizophrenia

(2009) Shane E McCarthy et al.   NATURE GENETICS

Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

(2009) Nurit Ballas et al.   NATURE NEUROSCIENCE

Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007

(2009) M. D. Kogan et al.   PEDIATRICS

Mouse neurexin-1  deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments

(2009) M. R. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copy-number variants in neurodevelopmental disorders: promises and challenges

(2009) Alison K. Merikangas et al.   TRENDS IN GENETICS

The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

(2009) Catalina Betancur et al.   TRENDS IN NEUROSCIENCES

Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene

(2008) Maricela Alarcón et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Common Genetic Variant in the Neurexin Superfamily Member CNTNAP2 Increases Familial Risk of Autism

(2008) Dan E. Arking et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Cytogenetic Analysis and Resequencing of Contactin Associated Protein-Like 2 in Autism Spectrum Disorders

(2008) Betul Bakkaloglu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder

(2008) Daniel B. Campbell et al.   Autism Research

Autism and Brain Development

(2008) Christopher A. Walsh et al.   CELL

MET and autism susceptibility: family and case–control studies

(2008) Inês Sousa et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A partial loss of function allele of Methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

(2008) R. C. Samaco et al.   HUMAN MOLECULAR GENETICS

Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice

(2008) I. Bureau et al.   JOURNAL OF NEUROSCIENCE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Advances in autism genetics: on the threshold of a new neurobiology

(2008) Brett S. Abrahams et al.   NATURE REVIEWS GENETICS

The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13

(2008) Amber Hogart et al.   NEUROBIOLOGY OF DISEASE

A Functional Genetic Link between Distinct Developmental Language Disorders

(2008) Sonja C. Vernes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association between Microdeletion and Microduplication at 16p11.2 and Autism

(2008) Lauren A. Weiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA