Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1β and suppressor of cytokine signalling-1 in mouse pancreatic beta cells

(2010) Panagiotis D. Venieratos et al.   CELLULAR SIGNALLING

Mitochondria mediated cell death in diabetes

(2009) Gyorgy Szabadkai et al.   APOPTOSIS

Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6

(2009) Amanda C. Korchnak et al.   CELLULAR SIGNALLING

Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue

(2009) Shigeki Miyamoto et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Glucose Regulates Steady-state Levels of PDX1 via the Reciprocal Actions of GSK3 and AKT Kinases

(2009) Rohan K. Humphrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing Mitogen-activated Protein 4 Kinase 4 (MAP4K4) Protects Beta Cells from Tumor Necrosis Factor-α-induced Decrease of IRS-2 and Inhibition of Glucose-stimulated Insulin Secretion

(2009) Karim Bouzakri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIB3 is implicated in glucotoxicity- and oestrogen receptor-stress-induced β-cell apoptosis

(2008) Bo Qian et al.   JOURNAL OF ENDOCRINOLOGY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

Commitment in apoptosis: slightly dead but mostly alive

(2008) Clare Sheridan et al.   TRENDS IN CELL BIOLOGY

PKB and the mitochondria: AKTing on apoptosis

(2007) Arnaud Parcellier et al.   CELLULAR SIGNALLING