Drosophila as a model of wound healing and tissue regeneration in vertebrates

MicroRNA Epigenetics

(2011) Luckshman Bavan et al.   BIODRUGS

APC as a master regulator of intestinal homeostasis and transformation: From flies to vertebrates

(2011) Julia Cordero et al.   CELL CYCLE

The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus)

(2011) Shree Ram Singh et al.   CELL CYCLE

Role of c-Jun N-terminal kinase activation in blastema formation during planarian regeneration

(2011) Junichi Tasaki et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells

(2011) Na Xu et al.   DEVELOPMENTAL BIOLOGY

Ecdysteroids affectDrosophilaovarian stem cell niche formation and early germline differentiation

(2011) Annekatrin König et al.   EMBO JOURNAL

Polycomb group genes in stem cell self-renewal: A double-edged sword

(2011) Yulong Su et al.   Epigenetics

Cell wound repair inDrosophilaoccurs through three distinct phases of membrane and cytoskeletal remodeling

(2011) Maria Teresa Abreu-Blanco et al.   JOURNAL OF CELL BIOLOGY

Differential expression of microRNA patterns in planarian normal and regenerative tissues

(2011) Qing-Nan Tian et al.   MOLECULAR BIOLOGY REPORTS

MicroRNA181a plays a key role in hair cell regeneration in the avian auditory epithelium

(2011) Corey S. Frucht et al.   NEUROSCIENCE LETTERS

Endocytic and Recycling Endosomes Modulate Cell Shape Changes and Tissue Behaviour during Morphogenesis in Drosophila

(2011) Ana Margarida Mateus et al.   PLoS One

Clonogenic Neoblasts Are Pluripotent Adult Stem Cells That Underlie Planarian Regeneration

(2011) D. E. Wagner et al.   SCIENCE

Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid

(2010) Rui E. Castro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

(2010) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Rho-family small GTPases are required for cell polarization and directional sensing in Drosophila wound healing

(2010) Seung Hee Baek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nonmuscle myosin II localization is regulated by JNK during Drosophila larval wound healing

(2010) Young-Chang Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Imaginal discs: Renaissance of a model for regenerative biology

(2010) Cora Bergantiños et al.   BIOESSAYS

Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs

(2010) Enrique Blanco et al.   BMC DEVELOPMENTAL BIOLOGY

The Steroid Hormone Ecdysone Functions with Intrinsic Chromatin Remodeling Factors to Control Female Germline Stem Cells in Drosophila

(2010) Elizabeth T. Ables et al.   Cell Stem Cell

EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila

(2010) Huaqi Jiang et al.   Cell Stem Cell

Coupling of Apoptosis and L/R Patterning Controls Stepwise Organ Looping

(2010) Magali Suzanne et al.   CURRENT BIOLOGY

Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

(2010) Binnaz Kucuk Staley et al.   CURRENT BIOLOGY

The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis

(2010) R. Rousset et al.   DEVELOPMENT

The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

(2010) R. L. Shaw et al.   DEVELOPMENT

The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

(2010) P. Karpowicz et al.   DEVELOPMENT

Cell death-induced regeneration in wing imaginal discs requires JNK signalling

(2010) C. Bergantinos et al.   DEVELOPMENT

The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation

(2010) S. Bahri et al.   DEVELOPMENT

The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila

(2010) D. J. V. David et al.   DEVELOPMENT

Transcriptional control of stem cell maintenance in the Drosophila intestine

(2010) A. J. Bardin et al.   DEVELOPMENT

Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure

(2010) G. B. Blanchard et al.   DEVELOPMENT

Stem cell system in tissue regeneration in fish

(2010) Atsushi Kawakami   DEVELOPMENT GROWTH & DIFFERENTIATION

Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors

(2010) Gongping Sun et al.   DEVELOPMENTAL BIOLOGY

Expression of Drosophila Cabut during early embryogenesis, dorsal closure and nervous system development

(2010) Yaiza Belacortu et al.   GENE EXPRESSION PATTERNS

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Integrative approaches to morphogenesis: Lessons from dorsal closure

(2010) Nicole Gorfinkiel et al.   GENESIS

A Targeted UAS-RNAi Screen in Drosophila Larvae Identifies Wound Closure Genes Regulating Distinct Cellular Processes

(2010) C. Lesch et al.   GENETICS

Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo

(2010) Tina M. Chavoshi et al.   MECHANISMS OF DEVELOPMENT

Interaction between Ras V12 and scribbled clones induces tumour growth and invasion

(2010) Ming Wu et al.   NATURE

Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo

(2010) Xiaobo Wang et al.   NATURE CELL BIOLOGY

miRNAs in Newt Lens Regeneration: Specific Control of Proliferation and Evidence for miRNA Networking

(2010) Kenta Nakamura et al.   PLoS One

Apoptosis, Stem Cells, and Tissue Regeneration

(2010) A. Bergmann et al.   Science Signaling

MicroRNA Profiling in Mid- and Late-Gestational Fetal Skin: Implication for Scarless Wound Healing

(2010) Jie Cheng et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Daily genetic profiling indicates JAK/STAT signaling promotes early hepatic stellate cell transdifferentiation

(2010) Ashley M Lakner   WORLD JOURNAL OF GASTROENTEROLOGY

Use of the parabiotic model in studies of cutaneous wound healing to define the participation of circulating cells

(2010) Guodong Song et al.   WOUND REPAIR AND REGENERATION

JNK Signalling Controls Remodelling of the Segment Boundary through Cell Reprogramming during Drosophila Morphogenesis

(2010) Melanie Gettings et al.   PLOS BIOLOGY

Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling

(2009) Tatsushi Igaki   APOPTOSIS

The Scar-in-a-Jar: studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well

(2009) CZC Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

(2009) Sashwati Roy et al.   CARDIOVASCULAR RESEARCH

Closing in on Mechanisms of Tissue Morphogenesis

(2009) Matteo Rauzi et al.   CELL

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure

(2009) Jerome Solon et al.   CELL

Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

(2009) Alla Amcheslavsky et al.   Cell Stem Cell

Intestinal Stem Cells in Mammals and Drosophila

(2009) Andreu Casali et al.   Cell Stem Cell

miRNA regulation of cytokine genes

(2009) Ananthi J. Asirvatham et al.   CYTOKINE

Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferation

(2009) W.-C. Lee et al.   DEVELOPMENT

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc

(2009) A. Perez-Garijo et al.   DEVELOPMENT

Mechanical control of global cell behaviour during dorsal closure in Drosophila

(2009) N. Gorfinkiel et al.   DEVELOPMENT

JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30

(2009) Chloe Thomas et al.   DEVELOPMENTAL BIOLOGY

JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage

(2009) Katherine Beebe et al.   DEVELOPMENTAL BIOLOGY

Regenerative Growth in Drosophila Imaginal Discs Is Regulated by Wingless and Myc

(2009) Rachel K. Smith-Bolton et al.   DEVELOPMENTAL CELL

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

(2009) Rocio Sancho et al.   EMBO JOURNAL

Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes

(2009) Tanya Shaw et al.   EMBO REPORTS

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Genetic Screen in Drosophila melanogaster Uncovers a Novel Set of Genes Required for Embryonic Epithelial Repair

(2009) I. Campos et al.   GENETICS

MicroRNA in the immune system, microRNA as an immune system

(2009) Li-Fan Lu et al.   IMMUNOLOGY

Diverse miRNA spatial expression patterns suggest important roles in homeostasis and regeneration in planarians

(2009) Cristina Gonzalez-Estevez et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Tail Regeneration in Xenopus laevis as a Model for Understanding Tissue Repair

(2009) A.-S. Tseng et al.   JOURNAL OF DENTAL RESEARCH

Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster

(2009) S. R. Singh et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Cells keep a memory of their tissue origin during axolotl limb regeneration

(2009) Martin Kragl et al.   NATURE

The tyrosine kinase Stitcher activates Grainy head and epidermal wound healing in Drosophila

(2009) Shenqiu Wang et al.   NATURE CELL BIOLOGY

A Non-Redundant Role for Drosophila Mkk4 and Hemipterous/Mkk7 in TAK1-Mediated Activation of JNK

(2009) Peter Geuking et al.   PLoS One

Rab11 Helps Maintain Apical Crumbs and Adherens Junctions in the Drosophila Embryonic Ectoderm

(2009) Jeremiah F. Roeth et al.   PLoS One

Multiple transcription factor codes activate epidermal wound-response genes in Drosophila

(2009) J. C. Pearson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wound healing in oral mucosa results in reduced scar formation as compared with skin: Evidence from the red Duroc pig model and humans

(2009) Joyce W. Wong et al.   WOUND REPAIR AND REGENERATION

Paracrine Unpaired Signaling through the JAK/STAT Pathway Controls Self-renewal and Lineage Differentiation of Drosophila Intestinal Stem Cells

(2009) G. Lin et al.   Journal of Molecular Cell Biology

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

Effect of Wnt signaling pathway on wound healing

(2008) D.L. Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ronin Is Essential for Embryogenesis and the Pluripotency of Mouse Embryonic Stem Cells

(2008) Marion Dejosez et al.   CELL

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Signaling Molecules: The Pathogenic Role of the IL-6/STAT-3 Trans Signaling Pathway in Intestinal Inflammation and in Colonic Cancer

(2008) R. Atreya et al.   CURRENT DRUG TARGETS

Stem cell regulation by polycomb repressors: postponing commitment

(2008) Alexandra M Pietersen et al.   CURRENT OPINION IN CELL BIOLOGY

New regulators of vertebrate appendage regeneration

(2008) Viravuth P Yin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure

(2008) T. H. Millard et al.   DEVELOPMENT

Three genes control the timing, the site and the size of blastema formation in Drosophila

(2008) Kimberly D. McClure et al.   DEVELOPMENTAL BIOLOGY

Distinct Mechanisms of Apoptosis-Induced Compensatory Proliferation in Proliferating and Differentiating Tissues in the Drosophila Eye

(2008) Yun Fan et al.   DEVELOPMENTAL CELL

Stretching the limits: Stem cells in regeneration science

(2008) David L. Stocum et al.   DEVELOPMENTAL DYNAMICS

An innate immune response of blood cells to tumors and tissue damage in Drosophila

(2008) J. C. Pastor-Pareja et al.   Disease Models & Mechanisms

A Wingless and Notch double-repression mechanism regulates G1–S transition in the Drosophila wing

(2008) Héctor Herranz et al.   EMBO JOURNAL

Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos

(2008) Brian Stramer et al.   EMBO REPORTS

Developmental expression of Rab11, a small GTP-binding protein inDrosophilaepithelia

(2008) Satish Sasikumar et al.   GENESIS

Actomyosin purse strings: Renewable resources that make morphogenesis robust and resilient

(2008) Alice Rodriguez‐Diaz et al.   HFSP Journal

What is the cancer risk in Crohnʼs disease?

(2008) Hugh J. Freeman   INFLAMMATORY BOWEL DISEASES

Origin and proliferation of blastema cells during regeneration of Drosophila wing imaginal discs

(2008) Manel Bosch et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Transcriptional profiling defines the roles of ERK and p38 kinases in epidermal keratinocytes

(2008) Alix Gazel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

(2008) Guonan Lin et al.   NATURE

The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling

(2008) Shigeo Takashima et al.   NATURE

A two-tiered mechanism for stabilization and immobilization of E-cadherin

(2008) Matthieu Cavey et al.   NATURE

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

(2008) Matteo Rauzi et al.   NATURE CELL BIOLOGY

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

(2008) Shuang Chang et al.   Nature Chemical Biology

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic and Chemical Modifiers of a CUG Toxicity Model in Drosophila

(2008) Amparo Garcia-Lopez et al.   PLoS One

Apoptotic Force and Tissue Dynamics During Drosophila Embryogenesis

(2008) Y. Toyama et al.   SCIENCE

Generation and Regeneration of Cells of the Liver and Pancreas

(2008) K. S. Zaret et al.   SCIENCE

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Wnt5a-mediated non-canonical Wnt signalling regulates human endothelial cell proliferation and migration

(2007) Ching-wen Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS