Article
Chemistry, Medicinal
Tao Jia, Oumar Diane, Deepanjan Ghosh, Myriem Skander, Gaelle Fontaine, Pascal Retailleau, Joel Poupon, Jerome Bignon, Ytabelle Maga Moulai Siasia, Vincent Servajean, Nathalie Hue, Jean-Francois Betzer, Angela Marinetti, Sophie Bombard
Summary: This article introduces a new series of bimetallic platinum-(II) complexes with NHC-type bridging ligands, which exhibit cytotoxicity, cell accumulation, and DNA binding properties in cancerous cells. These complexes demonstrate significant radiosensitizing effects by inhibiting DNA repair mechanisms, leading to persistent accumulation of irradiation-induced DNA damages. This study provides the first in vitro evidence for the radiosensitizing properties of NHC-platinum complexes, suggesting their potential use in combined chemo-radiotherapy protocols.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Pui-Ki Wan, Ka-Chung Tong, Chun-Nam Lok, Chunlei Zhang, Xiao-Yong Chang, Kong-Hung Sze, Alice Sze Tsai Wong, Chi-Ming Che
Summary: A metal complex, Pt1a, has been found to interact with vimentin and inhibit tumor growth and metastasis, showing promise as an effective targeted chemotherapy for combating metastatic cancers.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Applied
Vanessa Vethacke, Vanessa Claus, Martin C. Dietl, Daniel Ehjeij, Arne Meister, Jonas F. Huber, Leon K. Paschai Darian, Matthias Rudolph, Frank Rominger, A. Stephen K. Hashmi
Summary: A variety of unsymmetric diaryl gold N-acyclic carbene (NAC) complexes were successfully synthesized by three different methods, allowing access to new complexes and overcoming previous limitations in the isonitrile route. These new complexes also proved to be successful as pre-catalysts in gold-catalyzed phenol synthesis.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Pharmacology & Pharmacy
Patricia Fernandez de Larrinoa, Jordan Parmentier, Antoine Kichler, Thierry Achard, Monique Dontenwill, Christel Herold-Mende, Sylvie Fournel, Benoit Frisch, Beatrice Heurtault, Stephane Bellemin-Laponnaz
Summary: A novel series of platinum(II) complexes modified with the mitochondria targeting group triphenylphosphonium were synthesized, which showed significantly higher anticancer activity on cancer stem cell line compared to oxaliplatin. Mechanistic studies revealed that these complexes altered mitochondrial function and induced atypical cell death.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Oliver Bysewski, Andreas Winter, Phil Liebing, Ulrich S. Schubert
Summary: N-Heterocyclic carbenes (NHCs) are widely used compounds, with benzimidazole and imidazole derivatives being commonly used. Caffeine, which contains an imidazole unit, has been used as a carbene-type ligand before, but its use in a tridentate bis-NHC system has not been reported. The ligand can be synthesized easily, and metal complexes can be obtained through silver-salt metathesis. Platinum(II) and palladium(II) complexes were successfully isolated, and the crystal structure of the platinum complex was analyzed. Luminescence was observed in both the solid state and solution for the Pt(II) complex.
Article
Chemistry, Inorganic & Nuclear
Clemens Kaussler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcantar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore
Summary: This study focuses on improving the design of metal complexes as stabilizers of noncanonical DNA secondary structures. A series of cyclic dinuclear Au(I) N-heterocyclic carbene complexes based on xanthine and benzimidazole ligands have been synthesized and characterized. The compounds show stabilization properties towards G-quadruplexes (G4s) and moderate antiproliferative activity in human cancer cells. The binding modes and free energy landscape of the most active compound have been studied using metadynamics.
INORGANIC CHEMISTRY
(2022)
Review
Chemistry, Inorganic & Nuclear
Sai Zhao, Zhibing Yang, Guizhi Jiang, Sheng Huang, Mianli Bian, Yunlong Lu, Wukun Liu
Summary: NHCs have been introduced as a new platform for the development of anticancer metal complexes, with platinum NHC complexes showing comparable activities to cisplatin and exhibiting different mechanisms of action, including the induction of biochemical hallmarks of immunogenic cell death (ICD) as a type II ICD inducer. These features make them promising candidates in the field of anticancer research.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Organic
Killari Satyam, Jakkula Ramarao, Surisetti Suresh
Summary: The NHC-catalyzed intramolecular benzoin condensation-oxidation allows for the expedient synthesis of diverse cyclic 1,2-diketones incorporated in dibenzo-fused seven-membered heterocycles in good to excellent yields under ambient conditions. The transformation appears to proceed through the benzoin intermediate followed by aerobic oxidation.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Thomas M. Kirse, Joschua Lueke, Ivan Maisuls, Alexander Hepp, Cristian A. Strassert
Summary: In this work, coordination compounds featuring caffeine-based carbene co-ligands and tridentate dianionic pincer luminophores were studied. The influence of different substituents on the photophysical properties was assessed. The results showed that the four luminophores performed similarly and cyclometallation improved the synthetic efficiency but was not essential for achieving high photoluminescence quantum yields. In summary, coordination chemical concepts based on natural products can lead to stable phosphorescent species with interesting excited-state properties.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Chemistry, Inorganic & Nuclear
Thomas Scattolin, Andrea Piccin, Matteo Mauceri, Flavio Rizzolio, Nicola Demitri, Vincenzo Canzonieri, Fabiano Visentin
Summary: Newly synthesized palladium allyl complexes exhibit lower antiproliferative activity, with similar anticancer activity in two ovarian cancer cell lines, suggesting a different mechanism of action compared to platinum-based anticancer drugs. Some compounds show lower cytotoxicity on normal cells and higher selectivity towards cancer cells. Comparing the IC50 values of NHC/PTA complexes and their trifluoromethyl congeners indicates similar antiproliferative activity against cancer cells, but the absence of the CF3 group decreases selectivity towards them.
Article
Biochemistry & Molecular Biology
Francesca Sacco, Matteo Tarchi, Giarita Ferraro, Antonello Merlino, Giorgio Facchetti, Isabella Rimoldi, Luigi Messori, Lara Massai
Summary: The study investigated the reactions of three novel platinum(II) complexes with model proteins through ESI MS analysis, revealing diverse reactivity patterns depending on the nature of the Pt complex and interacting proteins. The formation of protein-bound Pt fragments was identified, and crystal structures were used to determine the exact location of Pt binding sites, contributing to understanding the potential mechanisms of action of these innovative anticancer Pt complexes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Medicinal
Mianli Bian, Rong Fan, Zhibin Yang, Yanan Chen, Zhongren Xu, Yunlong Lu, Wukun Liu
Summary: The research introduces a new Pt(II)-NHC complex termed 2c, which exhibits potent anticancer activities in HCC cells and can induce cell death, potentially activating genes.
The study suggests that 2c is a type II ICD inducer, capable of inducing cell death in HCC cells by causing endoplasmic reticulum stress and generating reactive oxygen species.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Maria Ines P. S. Leitao, Maria Turos-Cabal, Ana Maria Sanchez-Sanchez, Clara S. B. Gomes, Federico Herrera, Vanesa Martin, Ana Petronilho
Summary: Platinum(II) complexes with N-heterocyclic carbenes based on guanosine and caffeine were synthesized by unassisted C-H oxidative addition, leading to the corresponding trans-hydride complexes. Platinum guanosine derivatives with triflate or bromide were also synthesized for structure-activity correlation. The hydride compounds showed high antiproliferative activity against all tested cell lines and changing the counterion had no significant effect. Increasing the bulkiness at N7 maintained the antiproliferative activity while decreasing toxicity for non-cancer cells.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Physical
Ricardo J. Alves, Laize Zaramello, Elvis N. Nishida, Frank H. Quina, Bruno S. Souza
Summary: In this study, we investigated the transient formation of N-heterocyclic carbenes (NHCs) in zwitterionic imidazolium sulfonate surfactants in a water environment. The formation of NHCs was accelerated above the critical micelle concentration, due to increased local concentration of hydroxide or deuteroxide ions. The rate of NHC formation could be controlled by the anions of added salts, which also affected the selectivity of anion binding to the micelle surface. The NHCs generated at the micelle surface promoted the selective oxidation of 4-nitrobenzaldehyde, demonstrating the importance of micellar microenvironment in controlling reactivity and selectivity in aqueous media.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Inorganic & Nuclear
Silvano R. Valandro, Ru He, James D. Bullock, Hadi Arman, Kirk S. Schanze
Summary: This study investigates the femto- and picosecond excited-state dynamics of a series of N-heterocyclic carbene ligand-containing platinum complexes, revealing ultrafast singlet to triplet intersystem crossing and subsequent relaxation processes influenced by ligand torsional modes and solvent viscosity. Experimental findings show that different conformers can be photoselected by varying excitation wavelengths, while density functional theory calculations suggest the impact of geometry and steric hindrance on the ground-state energy surface.
INORGANIC CHEMISTRY
(2021)
Article
Oncology
Wolfgang Walther, Dhiyaa Althagafi, Danielle Curran, Cillian O'Beirne, Cian Mc Carthy, Ingo Ott, Uttara Basu, Britta Buttner, Anja Sterner-Kock, Helge Mueller-Bunz, Goar Sanchez-Sanz, Xiangming Zhu, Matthias Tacke
Article
Chemistry, Multidisciplinary
Jing-Jing Zhang, Mohamed A. Abu el Maaty, Henrik Hoffmeister, Claudia Schmidt, Julienne K. Muenzner, Rainer Schobert, Stefan Wolfl, Ingo Ott
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Chemistry, Multidisciplinary
Maria Gil-Moles, Uttara Basu, Rolf Bussing, Henrik Hoffmeister, Sebastian Turck, Agnieszka Varchmin, Ingo Ott
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Pharmacology & Pharmacy
Dennis Bruening, Kathrin Hatlapatka, Verena Lier-Glaubitz, Vincent Andermark, Stephan Scherneck, Ingo Ott, Ingo Rustenbeck
Summary: The NADPH-thioredoxin system plays a critical role in maintaining beta cell viability, but may have a limiting effect on glucose-induced insulin secretion.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Katharina Butsch, Alexander Haseloer, Simon Schmitz, Ingo Ott, Julia Schur, Axel Klein
Summary: Three complexes containing the non-innocent anionic ligand opo(-) were synthesized and characterized using spectroscopic techniques. The compounds show distinct electronic and optical properties, with potential antiproliferative activities against cancer cell lines.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Medicinal
Rolf Buessing, Bianka Karge, Petra Lippmann, Peter G. Jones, Mark Broenstrup, Ingo Ott
Summary: The study demonstrates that gold complexes exhibit strong antibacterial effects against Gram-positive bacteria and efficiently inhibit bacterial thioredoxin reductase. Both gold(I) and gold(III) analogues show comparable efficacy in most assays.
Article
Chemistry, Inorganic & Nuclear
Daniel Menia, Holger Kopacka, Klaus Wurst, Thomas Mueller, Petra Lippmann, Ingo Ott, Benno Bildstein
Summary: Cobaltoceniumselenolate coordination with Au(I) metal centers results in highly colored, stable compounds with good anticancer activity against various standard cancer cell lines. Characterization of these complexes was done through various analytical techniques such as NMR, IR, UV-Vis, HR-MS and single crystal XRD.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Anja Busemann, Ingrid Flaspohler, Xue-Quan Zhou, Claudia Schmidt, Sina K. Goetzfried, Vincent H. S. van Rixel, Ingo Ott, Maxime A. Siegler, Sylvestre Bonnet
Summary: Two analogs complexes of a known ruthenium complex were synthesized and evaluated for their photochemistry and phototoxicity, showing higher cellular uptake and cytotoxicity than the conventional complex. The compounds were found to be promising candidates for photoactivated chemotherapy due to their enhanced cellular uptake and cytotoxicity after light activation.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2021)
Article
Oncology
Jerneja Kladnik, James P. C. Coverdale, Jakob Kljun, Hilke Burmeister, Petra Lippman, Francesca G. Ellis, Alan M. Jones, Ingo Ott, Isolda Romero-Canelon, Iztok Turel
Summary: Ovarian cancer is a common cancer in the developing world, and resistance to platinum-based anticancer agents is a growing concern in treatment. A new family of organoruthenium(II) pyrithione complexes were explored for their efficacy towards platinum-resistant ovarian cancer cells, showing high potency and a unique mechanism of action compared to platinum agents. This study highlights the development of next-generation anticancer agents that can overcome resistance to existing therapies and the potential of transition metal complexes in multi-targeting mechanisms.
Article
Chemistry, Applied
Thomas Scattolin, Petra Lippmann, Marek Belis, Kristof van Hecke, Ingo Ott, Steven P. Nolan
Summary: A straightforward synthetic route to new N-heterocyclic carbene (NHC)-gold-steroidyl complexes is reported, which displayed good cytotoxicity against cancer cells.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Tomer Babu, Hiba Ghareeb, Uttara Basu, Hemma Schueffl, Sarah Theiner, Petra Heffeter, Gunda Koellensperger, Norman Metanis, Valentina Gandin, Ingo Ott, Claudia Schmidt, Dan Gibson
Summary: Au-I-carbene and Pt-IV-Au-I-carbene prodrugs exhibit low to sub-mu M activity against various cancer cell lines and overcome cisplatin resistance. The most potent prodrug is achieved by linking a cisplatin-derived Pt-IV(phenylbutyrate) complex to an Au-I-phenylimidazolylidene complex 2. In vivo tests on Lewis Lung Carcinoma demonstrate that the prodrug Pt-IV(phenylbutyrate)-Au-I-carbene (7) and the co-administration of cisplatin:phenylbutyrate:2 efficiently inhibit tumor growth (approximately 95%), surpassing the effectiveness of 2 (75%) or cisplatin (84%), while only causing 5% body weight loss compared to 14% for 2, 20% for cisplatin, and >30% for the co-administration.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Inorganic & Nuclear
Reinhard Thaler, Holger Kopacka, Klaus Wurst, Thomas Mueller, Florian R. Neururer, Stephan Hohloch, Petra Lippmann, Ingo Ott, Benno Bildstein
Summary: New clathrochelate complexes of manganese, iron, and cobalt containing organometallic manganese moieties cymantrene or tromancenium were synthesized via self-assembly from dioximes, metal templates, and boronic acid pinacol esters. These complexes are air-stable, highly colored, oligometallic assemblies with complicated magnetic and electrochemical properties. The tetrametallic complexes with tromanceniumyl substituents exhibit promising anticancer activity against different tumor cell lines.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Maria Gil-Moles, Cillian O'Beirne, Igor V. V. Esarev, Petra Lippmann, Matthias Tacke, Jindrich Cinatl, Denisa Bojkova, Ingo Ott
Summary: The ongoing SARS-CoV-2 pandemic has led to a high demand for innovative antiviral drugs. In this study, silver NHC complexes with chloride or iodide ligands were found to be potent inhibitors of the SARS-CoV-2 papain-like protease (PLpro), but inactive against another SARS-CoV-2 protease, 3C-like protease (3CL(pro)). Mechanistic studies showed that the complexes could remove zinc from the zinc binding domain of PLpro, which was a relevant factor for their activity. In addition, enzyme kinetic experiments revealed that the complexes were uncompetitive inhibitors, offering advantages in selectivity. The silver NHC complexes with iodide ligands showed low or no host cell toxicity and showed strong effects on viral replication in SARS-CoV-2-infected cells, making them promising candidates for future antiviral drugs.
RSC MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Mihyun Park, Claudia Schmidt, Sebastian Tuerck, Franziska Hanusch, Simone V. Hirmer, Ingo Ott, Angela Casini, Shigeyoshi Inoue
Summary: A dinuclear gold(I) complex with a strongly donating bis-N-heterocyclic imine ligand was synthesized and characterized. It showed highly selective anticancer effects against non-small cell lung cancer cells, particularly A549 cells. The anticancer effects were not correlated with the amount of gold uptake by the cells but correlated with its selective inhibition of cancer cells overexpressing a specific enzyme.
Article
Chemistry, Multidisciplinary
Mauro Safir Filho, Thomas Scattolin, Pascal Dao, Nikolaos Tzouras, Rachid Benhida, Marina Saab, Kristof Van Hecke, Petra Lippmann, Anthony R. Martin, Ingo Ott, Steven P. Nolan
Summary: A simple and eco-friendly method for synthesizing gold-NHC complexes bearing different thiosugars was reported. The obtained complexes showed strong cytotoxic activities against selected cancer cell lines.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)