A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme

Genetic Targeting of Organ-Specific Blood VesselsNovelty and Significance

(2018) Wenjuan Pu et al.   CIRCULATION RESEARCH

Enhancing the precision of genetic lineage tracing using dual recombinases

(2017) Lingjuan He et al.   NATURE MEDICINE

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

(2016) Qi Chen et al.   Nature Communications

Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering

(2016) Madina Karimova et al.   Scientific Reports

Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes

(2015) Qiaozhen Liu et al.   CELL RESEARCH

Endocardium Contributes to Cardiac FatNovelty and Significance

(2015) Hui Zhang et al.   CIRCULATION RESEARCH

Expanding the power of recombinase-based labeling to uncover cellular diversity

(2015) N. W. Plummer et al.   DEVELOPMENT

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

(2014) Nina Schönhuber et al.   NATURE MEDICINE

Targeting cells with single vectors using multiple-feature Boolean logic

(2014) Lief E Fenno et al.   NATURE METHODS

How to Make a Heart Valve: From Embryonic Development to Bioengineering of Living Valve Substitutes

(2014) D. MacGrogan et al.   Cold Spring Harbor Perspectives in Medicine

Early patterning and specification of cardiac progenitors in gastrulating mesoderm

(2014) W Patrick Devine et al.   eLife

Lineage Tracing

(2012) Kai Kretzschmar et al.   CELL

Islet1 Derivatives in the Heart Are of Both Neural Crest and Second Heart Field Origin

(2012) Kurt A. Engleka et al.   CIRCULATION RESEARCH

Endocardial and Epicardial Epithelial to Mesenchymal Transitions in Heart Development and Disease

(2012) Alexander von Gise et al.   CIRCULATION RESEARCH

Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart

(2012) Andy Wessels et al.   DEVELOPMENTAL BIOLOGY

Atrioventricular valve development: New perspectives on an old theme

(2012) Annemarieke de Vlaming et al.   DIFFERENTIATION

Tracing Cells for Tracking Cell Lineage and Clonal Behavior

(2011) Margaret E. Buckingham et al.   DEVELOPMENTAL CELL

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Heart Valve Development

(2009) Michelle D. Combs et al.   CIRCULATION RESEARCH

Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart

(2009) Bin Zhou et al.   DEVELOPMENTAL BIOLOGY

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

A multifunctional reporter mouse line for Cre- and FLP-dependent lineage analysis

(2009) Masakazu Yamamoto et al.   GENESIS

Tbx18 and the fate of epicardial progenitors

(2009) Vincent M. Christoffels et al.   NATURE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Epicardium-Derived Cells in Development of Annulus Fibrosis and Persistence of Accessory Pathways

(2008) Denise P. Kolditz et al.   CIRCULATION

Origin and fate of cardiac mesenchyme

(2008) Brian S. Snarr et al.   DEVELOPMENTAL DYNAMICS

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

A myocardial lineage derives from Tbx18 epicardial cells

(2008) Chen-Leng Cai et al.   NATURE

Redefining the serotonergic system by genetic lineage

(2008) Patricia Jensen et al.   NATURE NEUROSCIENCE