Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(iii) N-methoxyalkylpyridylporphyrins

Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

(2010) Ines Batinić-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Acid–base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria

(2010) Tin Weitner et al.   DALTON TRANSACTIONS

Cationic Mn Porphyrins Change Their Action from anti- to pro-oxidative in the Presence of Cellular Reductants: Relevance to understanding the beneficial therapeutic effects of SOD mimics in vivo

(2010) Zrinka Rajic et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species: A radical role in development?

(2010) David Hernández-García et al.   FREE RADICAL BIOLOGY AND MEDICINE

A “Push−Pull” Mechanism for Heterolytic O−O Bond Cleavage in Hydroperoxo Manganese Porphyrins

(2010) Ning Jin et al.   INORGANIC CHEMISTRY

Superoxide dismutase activity of corrole metal complexes

(2009) Meital Eckshtain et al.   DALTON TRANSACTIONS

Antioxidants and Novel Therapeutics

(2009)   FREE RADICAL BIOLOGY AND MEDICINE

Lipophilicity of potent porphyrin-based antioxidants: Comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins

(2009) Ivan Kos et al.   FREE RADICAL BIOLOGY AND MEDICINE

High Lipophilicity of meta Mn(III)N-Alkylpyridylporphyrin-Based Superoxide Dismutase Mimics Compensates for Their Lower Antioxidant Potency and Makes Them as Effective as Ortho Analogues in Protecting Superoxide Dismutase-DeficientEscherichia coli

(2009) Ivan Kos et al.   JOURNAL OF MEDICINAL CHEMISTRY

Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance

(2009) T. Doyle et al.   NEUROSCIENCE

SOD-like activity of Mn(II) β-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself

(2008) Gilson DeFreitas-Silva et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Pharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP5+, in plasma and major organs of B6C3F1 mice

(2008) Ivan Spasojević et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes

(2008) Júlio S. Rebouças et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

(2008) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA