Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions

Proteasomal Degradation Resolves Competition between Cell Polarization and Cellular Wound Healing

(2012) Keiko Kono et al.   CELL

Kinesin-13 and Tubulin Posttranslational Modifications Regulate Microtubule Growth in Axon Regeneration

(2012) Anindya Ghosh-Roy et al.   DEVELOPMENTAL CELL

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Alterations in sulfated chondroitin glycosaminoglycans following controlled cortical impact injury in mice

(2012) Jae-Hyuk Yi et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Trk Activation of the ERK1/2 Kinase Pathway Stimulates Intermediate Chain Phosphorylation and Recruits Cytoplasmic Dynein to Signaling Endosomes for Retrograde Axonal Transport

(2012) D. J. Mitchell et al.   JOURNAL OF NEUROSCIENCE

Dynactin's pointed-end complex is a cargo-targeting module

(2012) Ting-Yu Yeh et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple modes of cytoplasmic dynein regulation

(2012) Richard B. Vallee et al.   NATURE CELL BIOLOGY

Dynein dynamics

(2012) Peter Höök et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy

(2012) M. B. Harms et al.   NEUROLOGY

The p150Glued CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini

(2012) Thomas E. Lloyd et al.   NEURON

Dynactin Is Required for Transport Initiation from the Distal Axon

(2012) Armen J. Moughamian et al.   NEURON

Candesartan, an Angiotensin II AT1-Receptor Blocker and PPAR-γ Agonist, Reduces Lesion Volume and Improves Motor and Memory Function After Traumatic Brain Injury in Mice

(2012) Sonia Villapol et al.   NEUROPSYCHOPHARMACOLOGY

Reconstitution of the human cytoplasmic dynein complex

(2012) M. Trokter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling

(2012) Strahil Iv. Pastuhov et al.   Nature Communications

Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons

(2012) Bing Zhou et al.   Cell Reports

Mouse Brain PSA-NCAM Levels Are Altered by Graded-Controlled Cortical Impact Injury

(2012) Craig S. Budinich et al.   NEURAL PLASTICITY

Exome Sequencing Identifies a DYNC1H1 Mutation in a Large Pedigree with Dominant Axonal Charcot-Marie-Tooth Disease

(2011) Michael N. Weedon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeting 14-3-3zeta in cancer therapy

(2011) X Yang et al.   CANCER GENE THERAPY

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles

(2011) Sandra E. Encalada et al.   CELL

Quantitative analysis of Pac1/LIS1-mediated dynein targeting: Implications for regulation of dynein activity in budding yeast

(2011) Steven M. Markus et al.   Cytoskeleton

Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin

(2011) Richard J. McKenney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p25 subunit of the dynactin complex is required for dynein–early endosome interaction

(2011) Jun Zhang et al.   JOURNAL OF CELL BIOLOGY

High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport

(2011) Julie Y. Yi et al.   JOURNAL OF CELL BIOLOGY

Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse

(2011) G. T. Banks et al.   JOURNAL OF NEUROSCIENCE

A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons

(2011) J. P. Pandey et al.   JOURNAL OF NEUROSCIENCE

Lithium Ameliorates Neurodegeneration, Suppresses Neuroinflammation, and Improves Behavioral Performance in a Mouse Model of Traumatic Brain Injury

(2011) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency

(2011) P-S Cheah et al.   MOLECULAR PSYCHIATRY

Axon Regeneration Pathways Identified by Systematic Genetic Screening in C. elegans

(2011) Lizhen Chen et al.   NEURON

Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit

(2011) C L Neal et al.   ONCOGENE

Evidence that a Panel of Neurodegeneration Biomarkers Predicts Vasospasm, Infarction, and Outcome in Aneurysmal Subarachnoid Hemorrhage

(2011) Robert Siman et al.   PLoS One

14-3-3 proteins in neurodegeneration

(2011) Petra Steinacker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance

(2010) Max A. Tischfield et al.   CELL

Linking molecular motors to membrane cargo

(2010) Anna Akhmanova et al.   CURRENT OPINION IN CELL BIOLOGY

Delivery of GABAARs to Synapses Is Mediated by HAP1-KIF5 and Disrupted by Mutant Huntingtin

(2010) Alison E. Twelvetrees et al.   NEURON

Mouse Cytoplasmic Dynein Intermediate Chains: Identification of New Isoforms, Alternative Splicing and Tissue Distribution of Transcripts

(2010) Anna Kuta et al.   PLoS One

Coordinating mitosis with cell polarity: Molecular motors at the cell cortex

(2010) Jeffrey K. Moore et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Refining the phenotype of α-1a Tubulin (TUBA1A) mutation in patients with classical lissencephaly

(2009) DJ Morris-Rosendahl et al.   CLINICAL GENETICS

A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

(2009) E. Perlson et al.   JOURNAL OF NEUROSCIENCE

Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria

(2009) Xavier Hubert Jaglin et al.   NATURE GENETICS

DCTN1 mutations in Perry syndrome

(2009) Matthew J Farrer et al.   NATURE GENETICS

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration

(2009) J. K. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport

(2009) Qiangge Zhang et al.   TRAFFIC

Neuronal Polarization: Old Cells Can Learn New Tricks

(2008) Eric S. Sweet et al.   CURRENT BIOLOGY

Plasticity of Polarization: Changing Dendrites into Axons in Neurons Integrated in Neuronal Circuits

(2008) Susana Gomis-Rüth et al.   CURRENT BIOLOGY

Action in the axon: generation and transport of signaling endosomes

(2008) Katharina E Cosker et al.   CURRENT OPINION IN NEUROBIOLOGY

Nerve injury signaling

(2008) Namiko Abe et al.   CURRENT OPINION IN NEUROBIOLOGY

Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin

(2008) E. S. Chevalier-Larsen et al.   HUMAN MOLECULAR GENETICS

A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes

(2008) Junghoon Ha et al.   JOURNAL OF CELL BIOLOGY

Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death

(2008) H. S. Ilieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA