Review
Pharmacology & Pharmacy
Huanhuan Pang, Zeping Hu
Summary: Emerging evidence has shown the vital role of metabolism in various diseases or disorders. Metabolomics provides a comprehensive understanding of metabolism in biological systems. With advanced analytical techniques, metabolomics has significant value in basic drug research, including understanding disease mechanisms and identifying drug targets.
ACTA PHARMACEUTICA SINICA B
(2023)
Review
Polymer Science
Saleh O. Alaswad, Amira S. Mahmoud, Prabhakarn Arunachalam
Summary: The rising significance and rapid progress of biopolymers, a distinctive class of polymeric materials, have been driven by their tunable electrical conductivity and biodegradability characteristics. This article discusses the recent advancements and applications of biodegradable polymers, with a focus on their use in drug delivery, tissue engineering, and wound healing.
Article
Medicine, Research & Experimental
Xueran Xiao, Hui Li, Lijian Zhao, Yanfen Zhang, Zhongcheng Liu
Summary: Aptamers are single stranded oligonucleotides with specific recognition and binding ability to target molecules. They have advantages of low molecular weight, easy modification and high stability. Aptamers play important roles in promoting food safety, monitoring the environment, basic research, and have great potential in clinical diagnosis and therapeutic drugs.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Review
Pharmacology & Pharmacy
Alexandra Pusta, Mihaela Tertis, Izabell Craciunescu, Rodica Turcu, Simona Mirel, Cecilia Cristea
Summary: This review provides a critical overview of recent advancements in the use of magnetic nanoparticles in drug delivery, including their classification, characteristics, synthesis and functionalization methods, limitations, and examples of magnetic drug delivery systems incorporating chemotherapeutics or RNA.
Article
Chemistry, Physical
Lijuan Wang, Yushuang Shang, Jie Zhang, Jiang Yuan, Jian Shen
Summary: The development of keratin-based biomaterials provides a valuable approach for addressing environmental pollutants and transforming waste into wealth. The properties and biomedical applications of keratin biomaterials, such as drug delivery, wound healing, and tissue engineering, are extensively discussed in this review, offering valuable insights for further research and development.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Review
Chemistry, Medicinal
Jian Song, Mingzheng Hu, Jun Zhou, Songbo Xie, Tianliang Li, Yan Li
Summary: Targeted protein degradation (TPD) is a promising therapeutic approach that offers advantages over traditional inhibitors. This method relies on cell self-degradation mechanisms and can be used to target dysregulated proteins. Various TPD strategies have been developed and show potential for drug discovery.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Min-Soo Hwang, Jae-Hyuck Choi, Kwang-Yong Jeong, Kyoung-Ho Kim, Ha-Reem Kim, Jae-Pil So, Hoo-Cheol Lee, Jungkil Kim, Soon-Hong Kwon, Hong-Gyu Park
Summary: High quality factor and small mode volume in nanocavities enable efficient nanophotonic devices with low power consumption, strong nonlinearity, and high modulation speed. Single nanocavity designs include semiconductor nanowires, plasmonic cavities, and quasi-bound states in the continuum (quasi-BIC); nanocavity array designs include BIC cavities, parity-time symmetry coupled cavities, and photonic topological cavities, offering various options for laser applications.
CHEMICAL COMMUNICATIONS
(2021)
Review
Chemistry, Multidisciplinary
Michael D. Jorgensen, Jean Chmielewski
Summary: This article describes the strategies for association of coiled-coil building blocks and their biomedical applications. These systems have proven to be useful in protein storage, cargo binding and delivery, three-dimensional cell culturing, and vaccine development, showing high promise for significant biomedical impact.
CHEMICAL COMMUNICATIONS
(2022)
Review
Chemistry, Applied
Jong Min An, Kyung Oh Jung, Myung Sook Oh, Dokyoung Kim
Summary: The correlation between diseases and acetylcholinesterase (AChE) has been emphasized in the medical field. AChE-responsive fluorescent probes can enhance the prevention of unexpected human diseases. This review discusses recent advances in AChE-responsive fluorescent probes for real-time detection of AChE expression and activity, categorized based on sensing rationale. Photophysical properties and proof-of-concept visualization studies are also summarized. It is hoped that this review will inspire the development of AChE-responsive fluorescent probes and contribute to improving global health conditions.
Article
Materials Science, Multidisciplinary
Feng Pan, Muhammad Khan, Ahmed H. Ragab, Elisha Javed, Hessa A. Alsalmah, Idrees Khan, Tongfei Lei, Amjad Hussain, Ahmed Mohamed, Amir Zada, Mohd Zahid Ansari
Summary: Nanodiamonds have attracted significant attention from researchers due to their unique attributes and wide range of applications in various fields of science. These attributes include biocompatibility, easy production, chemical inertness, rich surface chemistry, small size, and fluorescence resistance. In biomedical sciences, nanodiamonds have shown promise in diagnostics, drug delivery, and manufacturing of surgical instruments, tissue engineering scaffolds, and antimicrobial agents. This review discusses the benefits of nanodiamonds, their applications in different fields, and the importance of purification, synthesis, processing, and surface functionalization. It also covers recent advances in biomedical and biological sciences.
MATERIALS & DESIGN
(2023)
Review
Chemistry, Analytical
Yufeng Jiao, Liyang Gao, Yaru Ji, Wu Liu
Summary: Single-cell analysis (SCA) is a powerful tool in drug development, allowing the detection of cellular heterogeneity and providing unique insights into complex biological processes. It has been widely used to uncover the origin of drug resistance, identify new drug targets, accelerate drug screening, and predict drug response.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Applied
Liangpeng Zeng, Xinxing Lin, Ping Li, Fa-Qian Liu, Hui Guo, Wei-Hua Li
Summary: This review focuses on the current advances of organogels, summarizing fundamental understandings and emerging applications, as well as addressing the remaining challenges and future prospects.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Engineering, Electrical & Electronic
Roselien Vercauteren, Gilles Scheen, Jean-Pierre Raskin, Laurent A. Francis
Summary: Porous silicon membranes (PSiMs) show great potential for various applications and have seen progress in different areas, however, they still face challenges in terms of integration.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Review
Chemistry, Multidisciplinary
Wenbo Ming, Harjeet S. Soor, Xiaocui Liu, Alina Trofimova, Andrei K. Yudin, Todd B. Marder
Summary: Alpha-aminoboronic acids and their derivatives are widely used as bioactive agents, with several compounds approved by the FDA as protease inhibitors. In organic synthesis, they are important reagents for the synthesis of chiral molecules and valuable organic compounds.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
Sachchidanand Soaham Gupta, Vivek Mishra, Maumita Das Mukherjee, Parveen Saini, Kumar Rakesh Ranjan
Summary: Amino acids have emerged as promising biomaterials for synthesizing functional polymers, offering a wide range of applications in drug delivery, tissue engineering, and biosensing. These polymers, such as polyamides, polyesters, and polyurethanes, allow for control of functionality, conjugation, crosslinking, and mechanical/thermal properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
