Schistosomiasis

Modeling the Effect of Chronic Schistosomiasis on Childhood Development and the Potential for Catch-Up Growth with Different Drug Treatment Strategies Promoted for Control of Endemic Schistosomiasis

(2011) David Gurarie et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni

(2011) Luiza F Andrade et al.   BMC GENOMICS

A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

(2011) Rebecca A. Green et al.   CELL

Isothermal Microcalorimetry To Study Drugs against Schistosoma mansoni

(2011) T. Manneck et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Quantitative retrotransposon anchored PCR confirms transduction efficiency of transgenes in adult Schistosoma mansoni

(2011) Gabriel Rinaldi et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Schistosomiasis in travellers and migrants

(2011) Jan Clerinx et al.   Travel Medicine and Infectious Disease

Schistosomiasis in infants and preschool-aged children: Infection in a single Schistosoma haematobium and a mixed S. haematobium – S. mansoni foci of Niger

(2010) Amadou Garba et al.   ACTA TROPICA

Genetic Consequences of Mass Human Chemotherapy for Schistosoma mansoni: Population Structure Pre- and Post-Praziquantel Treatment in Tanzania

(2010) Alice J. Norton et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

In Vitro Praziquantel Test Capable of Detecting Reduced In Vivo Efficacy in Schistosoma mansoni Human Infections

(2010) Poppy H. L. Lamberton et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni

(2010) Elissaveta B. Tchoubrieva et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Efficacy and Safety of Mefloquine, Artesunate, Mefloquine‐Artesunate, and Praziquantel againstSchistosoma haematobium: Randomized, Exploratory Open‐Label Trial

(2010) Jennifer Keiser et al.   CLINICAL INFECTIOUS DISEASES

Schistosoma mansoni: Schistosomicidal effect of mefloquine and primaquine in vitro

(2010) M.C. Holtfreter et al.   EXPERIMENTAL PARASITOLOGY

Miltefosine, a promising novel agent for schistosomiasis mansoni

(2010) Maha M. Eissa et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

High Rate of Failure in Treatment of Imported Schistosomiasis

(2010) Marie Helleberg et al.   JOURNAL OF TRAVEL MEDICINE

Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel

(2010) Ravi S. Kasinathan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Schistosomula, pre-adults and adults of Schistosoma mansoni ingest fluorescence-labelled albumin in vitro and in vivo: implication for a drug-targeting model

(2010) M. C. HOLTFRETER et al.   PARASITOLOGY

Is there reduced susceptibility to praziquantel in Schistosoma japonicum? Evidence from China

(2010) WEI WANG et al.   PARASITOLOGY

Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum

(2010) Shu-hua Xiao et al.   PARASITOLOGY RESEARCH

Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach

(2010) Gregory J. Crowther et al.   PLoS Neglected Tropical Diseases

RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

(2010) Saša Štefanić et al.   PLoS Neglected Tropical Diseases

Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

(2010) Emily Peak et al.   PLoS Neglected Tropical Diseases

Comparison of Microscopy and Alamar Blue Reduction in a Larval Based Assay for Schistosome Drug Screening

(2010) Nuha R. Mansour et al.   PLoS Neglected Tropical Diseases

A Novel High Throughput Assay for Anthelmintic Drug Screening and Resistance Diagnosis by Real-Time Monitoring of Parasite Motility

(2010) Michael J. Smout et al.   PLoS Neglected Tropical Diseases

Improving draft assemblies by iterative mapping and assembly of short reads to eliminate gaps

(2010) Isheng J Tsai et al.   GENOME BIOLOGY

Parasites and poverty: The case of schistosomiasis

(2009) Charles H. King   ACTA TROPICA

Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome

(2009) David H Bos et al.   BMC GENOMICS

Image Analysis in High Content Screening

(2009) Antje Niederlein et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Prospects for the control of neglected tropical diseases by mass drug administration

(2009) Henk L Smits   Expert Review of Anti-Infective Therapy

Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel

(2009) Ravi S. Kasinathan et al.   FASEB JOURNAL

Unresolved issues in anthelmintic pharmacology for helminthiases of humans

(2009) Timothy G. Geary et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against Schistosomiasis

(2009) Ganesha Rai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rescuing the bottom billion through control of neglected tropical diseases

(2009) Peter J Hotez et al.   LANCET

The Schistosoma japonicum genome reveals features of host–parasite interplay

(2009)   NATURE

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002–2008

(2009) A. FENWICK et al.   PARASITOLOGY

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs

(2009) M. J. DOENHOFF et al.   PARASITOLOGY

In vitro and in vivo trematode models for chemotherapeutic studies

(2009) J. KEISER   PARASITOLOGY

Experimentally promising antischistosomal drugs: a review of some drug candidates not reaching the clinical use

(2009) Rashad A. Abdul-Ghani et al.   PARASITOLOGY RESEARCH

A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni

(2009) Conor R. Caffrey et al.   PLoS One

Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children

(2009) Mahamadou S. Sissoko et al.   PLoS One

Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni

(2009) Shona Wilson et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya

(2009) Carla L. Black et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

A Schistosome cAMP-Dependent Protein Kinase Catalytic Subunit Is Essential for Parasite Viability

(2009) Brett E. Swierczewski et al.   PLoS Neglected Tropical Diseases

Mefloquine—An Aminoalcohol with Promising Antischistosomal Properties in Mice

(2009) Jennifer Keiser et al.   PLoS Neglected Tropical Diseases

Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening

(2009) Maha-Hamadien Abdulla et al.   PLoS Neglected Tropical Diseases

Anti-schistosomal Intervention Targets Identified by Lifecycle Transcriptomic Analyses

(2009) Jennifer M. Fitzpatrick et al.   PLoS Neglected Tropical Diseases

Praziquantel Affects the Regulatory Myosin Light Chain of Schistosoma mansoni

(2008) M. Gnanasekar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evolutionary concepts in predicting and evaluating the impact of mass chemotherapy schistosomiasis control programmes on parasites and their hosts

(2008) Joanne P. Webster et al.   Evolutionary Applications

Towards an understanding of the mechanism of action of praziquantel

(2008) Anthony D. Aragon et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

(2008) Ahmed A Sayed et al.   NATURE MEDICINE

Genomic-scale prioritization of drug targets: the TDR Targets database

(2008) Fernán Agüero et al.   NATURE REVIEWS DRUG DISCOVERY

The burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe

(2008) N. Midzi et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Schistosomicidal activity of the antimalarial drug, mefloquine, in Schistosoma mansoni-infected mice

(2008) Luc Van Nassauw et al.   Travel Medicine and Infectious Disease

Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

(2008) Anton Simeonov et al.   PLoS Neglected Tropical Diseases