Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders

Central Nervous System Penetration of Antiretroviral Drugs: Pharmacokinetic, Pharmacodynamic and Pharmacogenomic Considerations

(2015) Eric H. Decloedt et al.   CLINICAL PHARMACOKINETICS

Proteostasis control by the unfolded protein response

(2015) Claudio Hetz et al.   NATURE CELL BIOLOGY

Myelin, myelin-related disorders, and psychosis

(2015) Michelle I. Mighdoll et al.   SCHIZOPHRENIA RESEARCH

Dimethyl Fumarate (Tecfidera)

(2014) Jineane V. Venci et al.   ANNALS OF PHARMACOTHERAPY

Remyelination and Multiple Sclerosis: Therapeutic Approaches and Challenges

(2014) Meredith D. Hartley et al.   Current Neurology and Neuroscience Reports

Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders

(2014) Alexander J. Gill et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian Target of Rapamycin Promotes Oligodendrocyte Differentiation, Initiation and Extent of CNS Myelination

(2014) S. E. Wahl et al.   JOURNAL OF NEUROSCIENCE

Early suppressive antiretroviral therapy in HIV infection is associated with measurable changes in the corpus callosum

(2014) Sean G. Kelly et al.   JOURNAL OF NEUROVIROLOGY

Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system

(2014) Cagla Akay et al.   JOURNAL OF NEUROVIROLOGY

Lipid domains control myelin basic protein adsorption and membrane interactions between model myelin lipid bilayers

(2014) D. W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurologic disease in HIV-infected children and the impact of combination antiretroviral therapy

(2014) Claudia S. Crowell et al.   REVIEWS IN MEDICAL VIROLOGY

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Update on the key developments of the neurologic complications in children infected with HIV

(2014) Jo M. Wilmshurst et al.   Current Opinion in HIV and AIDS

Evolving clinical phenotypes in HIV-associated neurocognitive disorders

(2014) Ned Sacktor et al.   Current Opinion in HIV and AIDS

CSF LPV concentrations and viral load in viral suppressed patients on LPV/r monotherapy given once daily

(2014) Juan Tiraboschi et al.   Journal of the International AIDS Society

Unfolded Protein Response Signaling and Metabolic Diseases

(2013) Jaemin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Brain Entry of HIV-1 Protease Inhibitors Is Facilitated When Used in Combination

(2013) Catia Marzolini et al.   MOLECULAR PHARMACEUTICS

Oxidative Stress and Mitochondrial Impairment After Treatment with Anti-HIV Drugs: Clinical Implications

(2012) Ana Blas-Garcia et al.   CURRENT PHARMACEUTICAL DESIGN

Enhanced extinction of cocaine seeking in brain-derived neurotrophic factor Val66Met knock-in mice

(2012) Lisa. A. Briand et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cognitive function after several years of antiretroviral therapy with stable central nervous system penetration score

(2012) Y Kahouadji et al.   HIV MEDICINE

Higher CNS Penetration-Effectiveness of Long-term Combination Antiretroviral Therapy Is Associated With Better HIV-1 Viral Suppression in Cerebrospinal Fluid

(2012) Alexia Cusini et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Infection of human pericytes by HIV-1 disrupts the integrity of the blood-brain barrier

(2012) Shinsuke Nakagawa et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Delayed Myelination in an Intrauterine Growth Retardation Model Is Mediated by Oxidative Stress Upregulating Bone Morphogenetic Protein 4

(2012) Mary V. Reid et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Antiretroviral neurotoxicity

(2012) Kevin Robertson et al.   JOURNAL OF NEUROVIROLOGY

Oral BG12 for treatment of relapsing–remitting MS

(2012) Volker Limmroth   Nature Reviews Neurology

Prolonged myelination in human neocortical evolution

(2012) D. J. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endoplasmic reticulum stress response in aging and age-related diseases

(2012) Marishka K. Brown et al.   Frontiers in Physiology

Canonical Wnt Signalling Requires the BMP Pathway to Inhibit Oligodendrocyte Maturation

(2011) Keith Feigenson et al.   ASN Neuro

Evidence for Time-Dependent Interactions between Ritonavir and Lopinavir/Ritonavir Plasma Levels Following P-Glycoprotein Inhibition in Sprague-Dawley Rats

(2011) Michael du Plooy et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The antiretroviral protease inhibitors indinavir and nelfinavir stimulate Mrp1-mediated GSH export from cultured brain astrocytes

(2011) Maria Brandmann et al.   JOURNAL OF NEUROCHEMISTRY

Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies

(2011) David F. Tate et al.   JOURNAL OF NEUROVIROLOGY

Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-1-Associated Neurocognitive Disorders

(2011) Alejandra Borjabad et al.   PLoS Pathogens

Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice

(2010) Paul J. Pistell et al.   ANTIVIRAL RESEARCH

Food Combination and Alzheimer Disease Risk

(2010) Yian Gu   ARCHIVES OF NEUROLOGY

Quantitative Diffusion Tensor Imaging Tractography Metrics are Associated with Cognitive Performance Among HIV-Infected Patients

(2010) David F. Tate et al.   Brain Imaging and Behavior

Antibody-mediated demyelination in experimental allergic encephalomyelitis is independent of complement membrane attack complex formation

(2010) S. PIDDLESDEN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Does highly active antiretroviral therapy improve neurocognitive function? A systematic review

(2010) John A Joska et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance

(2009) Christina M Marra et al.   AIDS

The transport of anti-HIV drugs across blood–CNS interfaces: Summary of current knowledge and recommendations for further research

(2009) Lavanya Varatharajan et al.   ANTIVIRAL RESEARCH

CHOP and the endoplasmic reticulum stress response in myelinating glia

(2009) Alexander Gow et al.   CURRENT OPINION IN NEUROBIOLOGY

Oxidative stress disrupts oligodendrocyte maturation

(2009) Heather Morein French et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Wnt signaling is sufficient to perturb oligodendrocyte maturation

(2009) Keith Feigenson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Callosal degradation in HIV-1 infection predicts hierarchical perception: A DTI study

(2009) Eva M. Müller-Oehring et al.   NEUROPSYCHOLOGIA

Neuropsychological Functioning and Antiretroviral Treatment in HIV/AIDS: A Review

(2009) Lucette A. Cysique et al.   NEUROPSYCHOLOGY REVIEW

Lovastatin induces the formation of abnormal myelin-like membrane sheets in primary oligodendrocytes

(2008) Olaf Maier et al.   GLIA

Human Immunodeficiency Virus Type 1 Infection Increases the In Vivo Capacity of Peripheral Monocytes To Cross the Blood-Brain Barrier into the Brain and the In Vivo Sensitivity of the Blood-Brain Barrier to Disruption by Lipopolysaccharide

(2008) H. Wang et al.   JOURNAL OF VIROLOGY

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS