The MITOS system predicts long-term survival in amyotrophic lateral sclerosis

Erythropoietin in amyotrophic lateral sclerosis: a multicentre, randomised, double blind, placebo controlled, phase III study

(2015) Giuseppe Lauria et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A phase II−III trial of olesoxime in subjects with amyotrophic lateral sclerosis

(2014) T. Lenglet et al.   EUROPEAN JOURNAL OF NEUROLOGY

Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial

(2014) Merit E Cudkowicz et al.   LANCET NEUROLOGY

Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?

(2014) Hiroshi Mitsumoto et al.   LANCET NEUROLOGY

Development and evaluation of a clinical staging system for amyotrophic lateral sclerosis

(2013) Adriano Chiò et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Evidence of multidimensionality in the ALSFRS-R Scale: a critical appraisal on its measurement properties using Rasch analysis

(2013) Franco Franchignoni et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial

(2013) Merit E Cudkowicz et al.   LANCET NEUROLOGY

Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial

(2013)   LANCET NEUROLOGY

Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS

(2013) Ettore Beghi et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

A study to evaluate safety and tolerability of repeated doses of tirasemtiv in patients with amyotrophic lateral sclerosis

(2013) Jeremy M. Shefner et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Lithium lacks effect on survival in amyotrophic lateral sclerosis: a phase IIb randomised sequential trial

(2012) Esther Verstraete et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A Randomized, Double Blind, Placebo-Controlled Trial of Pioglitazone in Combination with Riluzole in Amyotrophic Lateral Sclerosis

(2012) Luc Dupuis et al.   PLoS One

A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results

(2011) Francesco Saccà et al.   JOURNAL OF NEUROLOGY

Clinical diagnosis and management of amyotrophic lateral sclerosis

(2011) Orla Hardiman et al.   Nature Reviews Neurology

Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: Examining a more efficient trial design

(2011) R. G. Miller et al.   NEUROLOGY

Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

(2010) Swati P Aggarwal et al.   LANCET NEUROLOGY

Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial

(2010) A. Chio et al.   NEUROLOGY

A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis

(2009) Robert M. Pascuzzi et al.   Amyotrophic Lateral Sclerosis

Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: A double- blind, randomized, multicentre, placebo-controlled trial

(2009) Vincent Meininger et al.   Amyotrophic Lateral Sclerosis

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III

(2009) Petra Kaufmann et al.   ANNALS OF NEUROLOGY

Measuring function in advanced ALS: validation of ALSFRS-EX extension items

(2009) P. Wicks et al.   EUROPEAN JOURNAL OF NEUROLOGY

Creatine monohydrate in ALS: Effects on strength, fatigue, respiratory status and ALSFRS

(2008) Jeffrey Rosenfeld et al.   Amyotrophic Lateral Sclerosis

ALSFRS and appel ALS scores: Discordance with disease progression

(2008) Andrei Voustianiouk et al.   MUSCLE & NERVE

Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

(2008) E. J. Sorenson et al.   NEUROLOGY