Inflammation and Hypertension: New Understandings and Potential Therapeutic Targets

CMV Infection, TLR-2 and -4 Expression, and Cytokine Profiles in Early-Onset Preeclampsia with HELLP Syndrome

(2014) Fang Xie et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Association of Serum Concentration of TNFR1 With All-Cause Mortality in Patients With Type 2 Diabetes and Chronic Kidney Disease: Follow-up of the SURDIAGENE Cohort

(2014) Pierre-Jean Saulnier et al.   DIABETES CARE

CCL2-Dependent Macrophage Recruitment Is Critical for Mineralocorticoid Receptor-Mediated Cardiac Fibrosis, Inflammation, and Blood Pressure Responses in Male Mice

(2014) J.Z. Shen et al.   ENDOCRINOLOGY

Female Spontaneously Hypertensive Rats Have a Compensatory Increase in Renal Regulatory T Cells in Response to Elevations in Blood Pressure

(2014) Ashlee J. Tipton et al.   HYPERTENSION

Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

(2014) Cristián A. Amador et al.   HYPERTENSION

Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice

(2013) Xiao-xing Wang et al.   ACTA PHARMACOLOGICA SINICA

Toll-like receptors and damage-associated molecular patterns: novel links between inflammation and hypertension

(2013) Cameron G. McCarthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4

(2013) Chao-Fan Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction

(2013) Michael Hausding et al.   BASIC RESEARCH IN CARDIOLOGY

Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in l-NAME-induced hypertension

(2013) Daniel Sollinger et al.   CARDIOVASCULAR RESEARCH

Dendritic Cells in Cardiovascular Diseases

(2013) Anette Christ et al.   CIRCULATION

Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase

(2013) Jing Wu et al.   CIRCULATION RESEARCH

Potential role of Toll-like receptors in programming of vascular dysfunction

(2013) Jennifer A. Thompson et al.   CLINICAL SCIENCE

Immune mechanisms in hypertension and vascular injury

(2013) Ernesto L. Schiffrin   CLINICAL SCIENCE

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome

(2013) Shun-Min Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Immunosenescent CD8 + T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension

(2013) Jong-Chan Youn et al.   HYPERTENSION

Administration of Interleukin-17 Soluble Receptor C Suppresses T H 17 Cells, Oxidative Stress, and Hypertension in Response to Placental Ischemia During Pregnancy

(2013) Denise C. Cornelius et al.   HYPERTENSION

Abnormal High-Density Lipoprotein Induces Endothelial Dysfunction via Activation of Toll-like Receptor-2

(2013) Thimoteus Speer et al.   IMMUNITY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Toll-Like Receptors in Atherosclerosis

(2013) Mika Falck-Hansen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy

(2013) Miao Lin et al.   KIDNEY INTERNATIONAL

Unknown

(2013) Eileen Bauer et al.   MOLECULAR MEDICINE

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Toll-like receptors: sensing and reacting to diabetic injury in the kidney

(2013) M. Lin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Circulating dendritic cell precursors in chronic kidney disease: a cross-sectional study

(2013) Katharina Paul et al.   BMC Nephrology

Brain dendritic cells: biology and pathology

(2012) Paul M. D’Agostino et al.   ACTA NEUROPATHOLOGICA

Female spontaneously hypertensive rats have greater renal anti-inflammatory T lymphocyte infiltration than males

(2012) Ashlee J. Tipton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Superoxide Dismutase Mimetic, MnTE-2-PyP, Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension, Pulmonary Vascular Remodeling, and Activation of the NALP3 Inflammasome

(2012) Leah R. Villegas et al.   ANTIOXIDANTS & REDOX SIGNALING

Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

(2012) Hoanglan Nguyen et al.   CARDIOVASCULAR RESEARCH

Treatment With OPN-305, a Humanized Anti–Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs

(2012) Fatih Arslan et al.   Circulation-Cardiovascular Interventions

Recruitment of circulating dendritic cell precursors into the infarcted myocardium and pro-inflammatory response in acute myocardial infarction

(2012) Daniel Kretzschmar et al.   CLINICAL SCIENCE

Toll-like receptor 9 activation: a novel mechanism linking placenta-derived mitochondrial DNA and vascular dysfunction in pre-eclampsia

(2012) Styliani Goulopoulou et al.   CLINICAL SCIENCE

Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats

(2012) Gisele F. Bomfim et al.   CLINICAL SCIENCE

Evaluation of emerging biomarkers in cardiovascular risk stratification of hypertensive patients: a 2-year study

(2012) G. Derosa et al.   CURRENT MEDICAL RESEARCH AND OPINION

Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice

(2012) Christopher T. Chan et al.   HYPERTENSION

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice

(2012) Zhongyang Lu et al.   JOURNAL OF ENDOCRINOLOGY

Re(de)fining the dendritic cell lineage

(2012) Ansuman T Satpathy et al.   NATURE IMMUNOLOGY

Placental Toll-Like Receptor 3 and Toll-Like Receptor 7/8 Activation Contributes to Preeclampsia in Humans and Mice

(2012) Piyali Chatterjee et al.   PLoS One

Sex differences in primary hypertension

(2012) Kathryn Sandberg et al.   Biology of Sex Differences

Inflammation and Hypertension: The Interplay of Interleukin-6, Dietary Sodium, and the Renin-Angiotensin System in Humans

(2011) B. Chamarthi et al.   AMERICAN JOURNAL OF HYPERTENSION

Natural Regulatory T Cells Control Coronary Arteriolar Endothelial Dysfunction in Hypertensive Mice

(2011) Khalid Matrougui et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-10 Released by CD4 + CD25 + Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice

(2011) Modar Kassan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Emerging Role of Innate Immunity in the Heart and Vascular System

(2011) Douglas L. Mann   CIRCULATION RESEARCH

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

CD8+ CD28− and CD8+ CD57+ T cells and their role in health and disease

(2011) Marius Strioga et al.   IMMUNOLOGY

CD4+CD25+Foxp3+ regulatory T cells suppress cardiac fibrosis in the hypertensive heart

(2011) Peter Kanellakis et al.   JOURNAL OF HYPERTENSION

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

(2010) Antony Vinh et al.   CIRCULATION

Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension

(2010) Bernardo Rodriguez-Iturbe   Clinical and Experimental Nephrology

Changes in blood dendritic cell counts in relation to type of coronary artery disease and brachial endothelial cell function

(2010) Emily A. Van Vré et al.   CORONARY ARTERY DISEASE

Interleukin 6 Knockout Prevents Angiotensin II Hypertension

(2010) Michael W. Brands et al.   HYPERTENSION

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease

(2010) Reiko M. Onishi et al.   IMMUNOLOGY

Impaired Function of Dendritic Cells Deficient in Angiotensin II Type 1 Receptors

(2010) K. Nahmod et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TLR2 and TLR4 in Ischemia Reperfusion Injury

(2010) F. Arslan et al.   MEDIATORS OF INFLAMMATION

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus

(2010) Cristiana Guiducci et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Development and function of TH17 cells in health and disease

(2009) Jennifer Louten et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity

(2009) Andrés A. Herrada et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity

(2008) Chun Kwok Wong et al.   CLINICAL IMMUNOLOGY