Polycystic Ovary Syndrome as a Paradigm for Prehypertension, Prediabetes, and Preobesity
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Title
Polycystic Ovary Syndrome as a Paradigm for Prehypertension, Prediabetes, and Preobesity
Authors
Keywords
Adipose tissue dysfunction, Endothelial dysfunction, Gestational diabetes, Hyperandrogenism, Insulin resistance, Obesity, Oxidative stress, Polycystic ovary syndrome, Pathogenesis, Pregnancy-induced hypertension, Sympathetic overactivity, Type 2 diabetes mellitus, Hypertension
Journal
CURRENT HYPERTENSION REPORTS
Volume 16, Issue 12, Pages -
Publisher
Springer Nature
Online
2014-10-10
DOI
10.1007/s11906-014-0500-6
References
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Note: Only part of the references are listed.- Gestational Exposure to Elevated Testosterone Levels Induces Hypertension via Heightened Vascular Angiotensin II Type 1 Receptor Signaling in Rats1
- (2014) Vijayakumar Chinnathambi et al. BIOLOGY OF REPRODUCTION
- Increased risk of preterm delivery and pre-eclampsia in women with polycystic ovary syndrome and hyperandrogenaemia
- (2014) KV Naver et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Glucose-induced inhibition of the appetitive brain response to visual food cues in polycystic ovary syndrome patients
- (2014) Dean A. Van Vugt et al. BRAIN RESEARCH
- Practice Patterns in Screening for Metabolic Disease in Women with PCOS of Diverse Race-Ethnic Backgrounds
- (2014) Melanie Mott et al. Endocrine Practice
- β-Cell Induction In Vivo in Severely Diabetic Male Mice by Changing the Circulating Levels and Pattern of the Ratios of Estradiol to Androgens
- (2014) Akari Inada et al. ENDOCRINOLOGY
- Excess mortality in mothers of patients with polycystic ovary syndrome
- (2014) Y. V. Louwers et al. HUMAN REPRODUCTION
- Preconception predictors of gestational diabetes: a multicentre prospective cohort study on the predominant complication of pregnancy in polycystic ovary syndrome
- (2014) M. A. de Wilde et al. HUMAN REPRODUCTION
- Persistent Apparent Pancreatic β-Cell Defects in Premenarchal PCOS Relatives
- (2014) Laura C. Torchen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2014) Frank González et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Obesity-Associated Melanocortin-4 Receptor Mutations Are Associated With Changes in the Brain Response to Food Cues
- (2014) Agatha A. van der Klaauw et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Parent-of-Origin Effects on Glucose Homeostasis in Polycystic Ovary Syndrome
- (2014) Kristen Kobaly et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dihydrotestosterone deteriorates cardiac insulin signaling and glucose transport in the rat model of polycystic ovary syndrome
- (2014) Snežana Tepavčević et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Effects of iron overload on chronic metabolic diseases
- (2014) José Manuel Fernández-Real et al. Lancet Diabetes & Endocrinology
- Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptors
- (2013) Megan M. Wenner et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Developmental androgen excess programs sympathetic tone and adipose tissue dysfunction and predisposes to a cardiometabolic syndrome in female mice
- (2013) Kazunari Nohara et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Prenatal Testosterone Induces Sex-Specific Dysfunction in Endothelium-Dependent Relaxation Pathways in Adult Male and Female Rats1
- (2013) Vijayakumar Chinnathambi et al. BIOLOGY OF REPRODUCTION
- miRNA-93 Inhibits GLUT4 and Is Overexpressed in Adipose Tissue of Polycystic Ovary Syndrome Patients and Women With Insulin Resistance
- (2013) Y.-H. Chen et al. DIABETES
- Human Leukocyte/Endothelial Cell Interactions and Mitochondrial Dysfunction in Type 2 Diabetic Patients and Their Association With Silent Myocardial Ischemia
- (2013) A. Hernandez-Mijares et al. DIABETES CARE
- Hepcidin levels in diabetes mellitus and polycystic ovary syndrome
- (2013) A. H. Sam et al. DIABETIC MEDICINE
- Lipokines and oxysterols: Novel adipose-derived lipid hormones linking adipose dysfunction and insulin resistance
- (2013) Giuseppe Murdolo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Sexual dimorphism in adipose tissue function as evidenced by circulating adipokine concentrations in the fasting state and after an oral glucose challenge
- (2013) M. Luque-Ramirez et al. HUMAN REPRODUCTION
- Advanced glycation end products and their relevance in female reproduction
- (2013) Z. Merhi HUMAN REPRODUCTION
- Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp
- (2013) N. K. Stepto et al. HUMAN REPRODUCTION
- Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis
- (2013) Mora Murri et al. HUMAN REPRODUCTION UPDATE
- Testosterone Alters Maternal Vascular Adaptations
- (2013) Vijayakumar Chinnathambi et al. HYPERTENSION
- Office Blood Pressure, Ambulatory Blood Pressure Monitoring, and Echocardiographic Abnormalities in Women With Polycystic Ovary Syndrome
- (2013) Manuel Luque-Ramírez et al. HYPERTENSION
- Global Adiposity and Thickness of Intraperitoneal and Mesenteric Adipose Tissue Depots Are Increased in Women With Polycystic Ovary Syndrome (PCOS)
- (2013) Susana Borruel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Basal and Meal-Stimulated Ghrelin, PYY, CCK Levels and Satiety in Lean Women With Polycystic Ovary Syndrome: Effect of Low-Dose Oral Contraceptive
- (2013) Gulcan Arusoglu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Effects of Polycystic Ovary Syndrome (PCOS), Sex Hormones, and Obesity on Circulating miRNA-21, miRNA-27b, miRNA-103, and miRNA-155 Expression
- (2013) Mora Murri et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Divergences in Insulin Resistance Between the Different Phenotypes of the Polycystic Ovary Syndrome
- (2013) Paolo Moghetti et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Nontargeted Proteomic Study of the Influence of Androgen Excess on Human Visceral and Subcutaneous Adipose Tissue Proteomes
- (2013) Rafael Montes-Nieto et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)
- (2013) M. Ángeles Martínez-García et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Adolescent Anovulation: Maturational Mechanisms and Implications
- (2013) Robert L. Rosenfield JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Gestational Diabetes and Type 2 Diabetes in Reproductive-Aged Women With Polycystic Ovary Syndrome
- (2013) A. E. Joham et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Glucose-Stimulated Oxidative Stress in Mononuclear Cells Is Related to Pancreatic β-Cell Dysfunction in Polycystic Ovary Syndrome
- (2013) Steven K. Malin et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype
- (2013) Eleni Armeni et al. JOURNAL OF HYPERTENSION
- Nitric oxide-mediated cutaneous microvascular function is impaired in polycystic ovary sydrome but can be improved by exercise training
- (2013) V. S. Sprung et al. JOURNAL OF PHYSIOLOGY-LONDON
- PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways
- (2013) Lei Zhang et al. Journal of Translational Medicine
- Proteomic and metabolomic approaches to the study of polycystic ovary syndrome
- (2013) María Insenser et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Advanced glycation end products as an upstream molecule triggers ROS-induced sFlt-1 production in extravillous trophoblasts: A novel bridge between oxidative stress and preeclampsia
- (2013) Q.T. Huang et al. PLACENTA
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- (2013) Q.T. Huang et al. PLACENTA
- Adiponectin and Its Receptors in the Ovary: Further Evidence for a Link between Obesity and Hyperandrogenism in Polycystic Ovary Syndrome
- (2013) Fabio V. Comim et al. PLoS One
- Androgens inhibit adipogenesis during human adipose stem cell commitment to preadipocyte formation
- (2013) Gregorio Chazenbalk et al. STEROIDS
- Animal models of the polycystic ovary syndrome phenotype
- (2013) Vasantha Padmanabhan et al. STEROIDS
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- (2012) E. Amengual-Cladera et al. BRITISH JOURNAL OF NUTRITION
- Metabolic Heterogeneity in Polycystic Ovary Syndrome Is Determined by Obesity: Plasma Metabolomic Approach Using GC-MS
- (2012) H. F. Escobar-Morreale et al. CLINICAL CHEMISTRY
- Pervasive developmental disorders in children of hyperandrogenic women with polycystic ovary syndrome: a longitudinal case-control study
- (2012) Stefano Palomba et al. CLINICAL ENDOCRINOLOGY
- The sympathetic nervous system in polycystic ovary syndrome: a novel therapeutic target?
- (2012) Andrew Lansdown et al. CLINICAL ENDOCRINOLOGY
- Polycystic Ovary Syndrome Is a Risk Factor for Type 2 Diabetes: Results From a Long-Term Prospective Study
- (2012) A. Gambineri et al. DIABETES
- The Risk of a Persistent Glucose Metabolism Impairment After Gestational Diabetes Mellitus Is Increased in Patients With Polycystic Ovary Syndrome
- (2012) S. Palomba et al. DIABETES CARE
- Cardiometabolic Aspects of the Polycystic Ovary Syndrome
- (2012) Harpal S. Randeva et al. ENDOCRINE REVIEWS
- Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
- (2012) Evanthia Diamanti-Kandarakis et al. ENDOCRINE REVIEWS
- Birth weight and polycystic ovary syndrome in adult life: a register-based study on 523,757 Danish women born 1973–1991
- (2012) Hanne Mumm et al. FERTILITY AND STERILITY
- Age-related differences in the reproductive and metabolic implications of polycystic ovarian syndrome: findings in an obese, United States population
- (2012) Erica B. Johnstone et al. GYNECOLOGICAL ENDOCRINOLOGY
- In Vivo β-Adrenergic Blockade by Propranolol Prevents Isoproterenol-induced Polycystic Ovary in Adult Rats
- (2012) S. Luna et al. HORMONE AND METABOLIC RESEARCH
- Prevalence of functional disorders of androgen excess in unselected premenopausal women: a study in blood donors
- (2012) R. Sanchon et al. HUMAN REPRODUCTION
- Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis
- (2012) S.S. Lim et al. HUMAN REPRODUCTION UPDATE
- Inflammation in Response to Glucose Ingestion Is Independent of Excess Abdominal Adiposity in Normal-Weight Women with Polycystic Ovary Syndrome
- (2012) Frank González et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- PCOS Is Associated with Increased CD11c Expression and Crown-Like Structures in Adipose Tissue and Increased Central Abdominal Fat Depots Independent of Obesity
- (2012) Zhi Hua Huang et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Adipocytokine profiles in a putative novel postmenopausal polycystic ovary syndrome (PCOS) phenotype parallel those in premenopausal PCOS: the Rancho Bernardo Study
- (2012) Andrew J. Krentz et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The effect of obesity on polycystic ovary syndrome: a systematic review and meta-analysis
- (2012) S. S. Lim et al. Obesity Reviews
- Polycystic ovary syndrome in adolescence: impaired glucose tolerance occurs across the spectrum of BMI
- (2012) Clare A Flannery et al. PEDIATRIC DIABETES
- Iron metabolism and the polycystic ovary syndrome
- (2012) Héctor F. Escobar-Morreale TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Sex differences in primary hypertension
- (2012) Kathryn Sandberg et al. Biology of Sex Differences
- Effects of Testosterone on Renal Function in Salt-Loaded Rats
- (2011) Jianping Hu et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Fetal programming of adult hypertension in female rat offspring exposed to androgens in utero
- (2011) K. Sathishkumar et al. EARLY HUMAN DEVELOPMENT
- Ovarian Hypertension: Polycystic Ovary Syndrome
- (2011) Rhonda Bentley-Lewis et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Endocrinology and Gynecology of Girls and Women with Low Birth Weight
- (2011) Lourdes Ibáñez et al. FETAL DIAGNOSIS AND THERAPY
- Diet composition and physical activity in overweight and obese premenopausal women with or without polycystic ovary syndrome
- (2011) Francisco Álvarez-blasco et al. GYNECOLOGICAL ENDOCRINOLOGY
- Carotid artery intima-media thickness in polycystic ovary syndrome: a systematic review and meta-analysis
- (2011) Michelle L. Meyer et al. HUMAN REPRODUCTION UPDATE
- Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance
- (2011) Victor M. Victor et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Cardiovascular Disease and Risk Factors in PCOS Women of Postmenopausal Age: A 21-Year Controlled Follow-Up Study
- (2011) Johanna Schmidt et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Role of Decreased Circulating Hepcidin Concentrations in the Iron Excess of Women with the Polycystic Ovary Syndrome
- (2011) Manuel Luque-Ramírez et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sex Hormone-Binding Globulin, Oligomenorrhea, Polycystic Ovary Syndrome, and Childhood Insulin at Age 14 Years Predict Metabolic Syndrome and Class III Obesity at Age 24 Years
- (2011) Charles J. Glueck et al. JOURNAL OF PEDIATRICS
- Endothelin B receptor contribution to peripheral microvascular function in women with polycystic ovary syndrome
- (2011) Megan M. Wenner et al. JOURNAL OF PHYSIOLOGY-LONDON
- FTO and MC4R Gene Variants Are Associated with Obesity in Polycystic Ovary Syndrome
- (2011) Kathryn G. Ewens et al. PLoS One
- Surgical management of metabolic dysfunction in PCOS
- (2011) Héctor F. Escobar-Morreale STEROIDS
- Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)
- (2010) Susanne Tan et al. BMC Medical Genetics
- The determinants of insulin sensitivity, β-cell function, and glucose tolerance are different in patients with polycystic ovary syndrome than in women who do not have hyperandrogenism
- (2010) Manuel Luque-Ramírez et al. FERTILITY AND STERILITY
- Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis
- (2010) Héctor F. Escobar-Morreale et al. FERTILITY AND STERILITY
- Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis
- (2010) Lisa J. Moran et al. HUMAN REPRODUCTION UPDATE
- Adipose Tissue Has Aberrant Morphology and Function in PCOS: Enlarged Adipocytes and Low Serum Adiponectin, But Not Circulating Sex Steroids, Are Strongly Associated with Insulin Resistance
- (2010) Louise Mannerås-Holm et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Treatment of Obstructive Sleep Apnea Improves Cardiometabolic Function in Young Obese Women with Polycystic Ovary Syndrome
- (2010) Esra Tasali et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Body Iron Stores and Glucose Intolerance in Premenopausal Women: Role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism
- (2009) M. A. Martinez-Garcia et al. DIABETES CARE
- Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking
- (2009) Manuel Luque-Ramírez et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Antiandrogenic Contraceptives Increase Serum Adiponectin in Obese Polycystic Ovary Syndrome Patients
- (2008) Manuel Luque-Ramírez et al. Obesity
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