The Pathophysiology of Preeclampsia Involves Altered Levels of Angiogenic Factors Promoted by Hypoxia and Autoantibody-Mediated Mechanisms1

Elevated Maternal IL-16 Levels, Enhanced IL-16 Expressions in Endothelium and Leukocytes, and Increased IL-16 Production by Placental Trophoblasts in Women with Preeclampsia

(2014) Y. Gu et al.   JOURNAL OF IMMUNOLOGY

Hypertension in Response to AT1-AA: Role of Reactive Oxygen Species in Pregnancy-Induced Hypertension

(2011) M. R. Parrish et al.   AMERICAN JOURNAL OF HYPERTENSION

Local Retention Versus Systemic Release of Soluble VEGF Receptor-1 Are Mediated by Heparin-Binding and Regulated by Heparanase

(2011) Shay Sela et al.   CIRCULATION RESEARCH

The Loss of Endoglin Promotes the Invasion of Extravillous Trophoblasts

(2011) Yukio Mano et al.   ENDOCRINOLOGY

Hypertension in Response to Placental Ischemia During Pregnancy

(2011) Babbette LaMarca et al.   HYPERTENSION

Autoantibody-Mediated IL-6-Dependent Endothelin-1 Elevation Underlies Pathogenesis in a Mouse Model of Preeclampsia

(2011) C. C. Zhou et al.   JOURNAL OF IMMUNOLOGY

The Effect of Immune Factors, Tumor Necrosis Factor- , and Agonistic Autoantibodies to the Angiotensin II Type I Receptor on Soluble fms-Like Tyrosine-1 and Soluble Endoglin Production in Response to Hypertension During Pregnancy

(2010) M. R. Parrish et al.   AMERICAN JOURNAL OF HYPERTENSION

An immunological insight into the origins of pre-eclampsia

(2010) E. Laresgoiti-Servitje et al.   HUMAN REPRODUCTION UPDATE

Autoantibody-Mediated Angiotensin Receptor Activation Contributes to Preeclampsia Through Tumor Necrosis Factor-α Signaling

(2010) Roxanna A. Irani et al.   HYPERTENSION

Upregulation of Urotensin II Receptor in Preeclampsia Causes In Vitro Placental Release of Soluble Vascular Endothelial Growth Factor Receptor 1 in Hypoxia

(2010) Phillip S. Gould et al.   HYPERTENSION

Role of extracellular signal-regulated kinase and AKT cascades in regulating hypoxia-induced angiogenic factors produced by a trophoblast-derived cell line

(2010) Daisuke Fujita et al.   JOURNAL OF ENDOCRINOLOGY

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis

(2010) Q. Huang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating free fetal nucleic acids in maternal plasma and preeclampsia

(2010) Barbora Vlková et al.   MEDICAL HYPOTHESES

Angiotensin Receptor Agonistic Autoantibody Is Highly Prevalent in Preeclampsia

(2009) Athar H. Siddiqui et al.   HYPERTENSION

A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

(2009) Christie P. Thomas et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia

(2009) Roxanna A. Irani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation

(2009) Xiaoli Yang et al.   JOURNAL OF HYPERTENSION

Autoimmune Disease in Lyn-Deficient Mice Is Dependent on an Inflammatory Environment Established by IL-6

(2009) E. Tsantikos et al.   JOURNAL OF IMMUNOLOGY

Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells

(2009) E. Tskitishvili et al.   MOLECULAR HUMAN REPRODUCTION

Preeclampsia: The Role of Angiogenic Factors in Its Pathogenesis

(2009) Alice Wang et al.   PHYSIOLOGY

A Novel Human-Specific Soluble Vascular Endothelial Growth Factor Receptor 1

(2008) Shay Sela et al.   CIRCULATION RESEARCH

Metal Transcription Factor-1 Is Involved in Hypoxia-Dependent Regulation of Placenta Growth Factor in Trophoblast-Derived Cells

(2008) Fumihito Nishimoto et al.   ENDOCRINOLOGY

Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (VEGFR-1) but not for soluble endoglin induction in villous trophoblast

(2008) C. Munaut et al.   HUMAN REPRODUCTION

Autoantibody From Women With Preeclampsia Induces Soluble Fms-Like Tyrosine Kinase-1 Production via Angiotensin Type 1 Receptor and Calcineurin/Nuclear Factor of Activated T-Cells Signaling

(2008) Cissy Chenyi Zhou et al.   HYPERTENSION

Autoantibodies to the Angiotensin Type I Receptor in Response to Placental Ischemia and Tumor Necrosis Factor α in Pregnant Rats

(2008) Babbette LaMarca et al.   HYPERTENSION

Adverse Perinatal Outcomes and Risk Factors for Preeclampsia in Women With Chronic Hypertension

(2008) Lucy C. Chappell et al.   HYPERTENSION

Activation of Local Chorionic Villi Angiotensin II Levels But Not Angiotensin (1-7) in Preeclampsia

(2008) Lauren Anton et al.   HYPERTENSION

Prevalence of Agonistic Autoantibodies Against the Angiotensin II Type 1 Receptor and Soluble fms-Like Tyrosine Kinase 1 in a Gestational Age–Matched Case Study

(2008) Florian Herse et al.   HYPERTENSION

T Cell-Independent and Toll-like Receptor-Dependent Antigen-Driven Activation of Autoreactive B Cells

(2008) Robin A. Herlands et al.   IMMUNITY

Anti-inflammatory effects of tumour necrosis factor (TNF)-α are mediated via TNF-R2 (p75) in tolerogenic transforming growth factor-β-treated antigen-presenting cells

(2008) Sharmila Masli et al.   IMMUNOLOGY

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

(2008) Maria Armaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

(2008) Cissy C Zhou et al.   NATURE MEDICINE

Endothelial Angiotensin II Generation Induced by Placenta-derived Factors From Preeclampsia

(2008) Yuping Wang et al.   Reproductive Sciences

Censoring of Autoreactive B Cell Development by the Pre-B Cell Receptor

(2008) R. A. Keenan et al.   SCIENCE

Placental Productions and Expressions of Soluble Endoglin, Soluble fms-Like Tyrosine Kinase Receptor-1, and Placental Growth Factor in Normal and Preeclamptic Pregnancies

(2007) Yang Gu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM