Animal Models in Obesity and Hypertension

Role of leptin and central nervous system melanocortins in obesity hypertension

(2013) Alexandre A. da Silva et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity

(2012) Aline M. Hilzendeger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension

(2012) Naoko Deji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Non-Communicable Disease: A Welcome and Long Needed Addition to the WHO’s 2012 World Heath Statistics

(2012) Jonathan Owen et al.   CURRENT HYPERTENSION REPORTS

Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques

(2012) P. Kievit et al.   DIABETES

The Development of Hypertension and Hyperaldosteronism in a Rodent Model of Life-Long Obesity

(2012) Carrie A. Northcott et al.   ENDOCRINOLOGY

Melanocortin 3/4 receptors in paraventricular nucleus modulate sympathetic outflow and blood pressure

(2012) Peng Li et al.   EXPERIMENTAL PHYSIOLOGY

Adipocyte Deficiency of Angiotensinogen Prevents Obesity-Induced Hypertension in Male Mice

(2012) Frederique Yiannikouris et al.   HYPERTENSION

Enhanced Adipose Afferent Reflex Contributes to Sympathetic Activation in Diet-Induced Obesity Hypertension

(2012) Xiao-Qing Xiong et al.   HYPERTENSION

Adipocytes Produce Aldosterone Through Calcineurin-Dependent Signaling Pathways

(2012) Ana M. Briones et al.   HYPERTENSION

Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats

(2012) Nathan T. Jenkins et al.   JOURNAL OF APPLIED PHYSIOLOGY

Evaluation of the Zucker Diabetic Fatty (ZDF) Rat as a Model for Human Disease Based on Urinary Peptidomic Profiles

(2012) Justyna Siwy et al.   PLoS One

Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study

(2012) Conall M O'Seaghdha et al.   BMC Endocrine Disorders

Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

(2011) Jussara M. do Carmo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice

(2011) Frederique Yiannikouris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system

(2011) Curt D. Sigmund   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Azilsartan treatment improves insulin sensitivity in obese spontaneously hypertensive Koletsky rats

(2011) M. Zhao et al.   DIABETES OBESITY & METABOLISM

Sitagliptin lowers glucagon and improves glucose tolerance in prediabetic obese SHROB rats

(2011) Brian Chen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Control of Blood Pressure, Appetite, and Glucose by Leptin in Mice Lacking Leptin Receptors in Proopiomelanocortin Neurons

(2011) Jussara M. do Carmo et al.   HYPERTENSION

Adipocyte-Derived Factors Regulate Vascular Smooth Muscle Cells Through Mineralocorticoid and Glucocorticoid Receptors

(2011) Aurelie Nguyen Dinh Cat et al.   HYPERTENSION

Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet

(2011) John H Dubinion et al.   JOURNAL OF HYPERTENSION

The role of the brain renin–angiotensin system in hypertension: Implications for new treatment

(2011) Yannick Marc et al.   PROGRESS IN NEUROBIOLOGY

Adipose Tissue–Specific Regulation of Angiotensinogen in Obese Humans and Mice: Impact of Nutritional Status and Adipocyte Hypertrophy

(2010) Shintaro Yasue et al.   AMERICAN JOURNAL OF HYPERTENSION

The Brain Renin-Angiotensin System Controls Divergent Efferent Mechanisms to Regulate Fluid and Energy Balance

(2010) Justin L. Grobe et al.   Cell Metabolism

Periadventitial Adipose Tissue Promotes Endothelial Dysfunction via Oxidative Stress in Diet-Induced Obese C57Bl/6 Mice

(2010) Juha Ketonen et al.   CIRCULATION JOURNAL

Calcineurin mediates the angiotensin II-induced aldosterone synthesis in the adrenal glands by up-regulation of transcription of the CYP11B2 gene

(2010) T. Yamashiro et al.   JOURNAL OF BIOCHEMISTRY

Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins

(2010) John E. Hall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity and Hypertension: Mechanisms, Cardio-Renal Consequences, and Therapeutic Approaches

(2009) Efrain Reisin et al.   MEDICAL CLINICS OF NORTH AMERICA

The adipose renin–angiotensin system: Role in cardiovascular disease

(2009) Sean Thatcher et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Animals models of MCH function and what they can tell us about its role in energy balance

(2009) Pavlos Pissios   PEPTIDES

Diabetic Hypertensive Leptin Receptor–Deficient db/db Mice Develop Cardioregulatory Autonomic Dysfunction

(2008) Andrey C. da Costa Goncalves et al.   HYPERTENSION