Melanocortin 3/4 receptors in paraventricular nucleus modulate sympathetic outflow and blood pressure

Sympathetic activation by chemical stimulation of white adipose tissues in rats

(2012) Zhen Shi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway

(2011) Daniela Valenti et al.   BIOCHEMICAL JOURNAL

Melanocortin MC4 receptor expression sites and local function

(2011) Jacqueline E. Siljee-Wong   EUROPEAN JOURNAL OF PHARMACOLOGY

Structure, function and regulation of the melanocortin receptors

(2011) Yingkui Yang   EUROPEAN JOURNAL OF PHARMACOLOGY

Responses of neurons in paraventricular nucleus to activation of cardiac afferents and acute myocardial ischaemia in rats

(2011) Bo Xu et al.   EXPERIMENTAL PHYSIOLOGY

Endogenous hydrogen peroxide in paraventricular nucleus mediates sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats

(2011) Yao Xu et al.   EXPERIMENTAL PHYSIOLOGY

Sympathetic Response to Insulin Is Mediated by Melanocortin 3/4 Receptors in the Hypothalamic Paraventricular Nucleus

(2011) Kathryn R. Ward et al.   HYPERTENSION

Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP – Protein kinase A pathway

(2011) Carla Caruso et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibition of Cardiac Sympathetic Afferent Reflex and Sympathetic Activity by Baroreceptor and Vagal Afferent Inputs in Chronic Heart Failure

(2011) Xian-Bing Gan et al.   PLoS One

Therapeutic strategies for targeting excessive central sympathetic activation in human hypertension

(2010) James P. Fisher et al.   EXPERIMENTAL PHYSIOLOGY

Neuronal nitric oxide synthase within paraventricular nucleus: blood pressure and baroreflex in two-kidney, one-clip hypertensive rats

(2010) Noreen F. Rossi et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin AT1receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats

(2010) Ai-Dong Chen et al.   EXPERIMENTAL PHYSIOLOGY

Methods of assessing vagus nerve activity and reflexes

(2010) Mark W. Chapleau et al.   HEART FAILURE REVIEWS

Sympathetic Function in Human Carriers of Melanocortin-4 Receptor Gene Mutations

(2010) Friedhelm Sayk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity

(2010) John H Dubinion et al.   JOURNAL OF HYPERTENSION

N-Methyl-d-aspartate glutamate receptors in the hypothalamic paraventricular nucleus modulate cardiac component of the baroreflex in unanesthetized rats

(2010) Carlos C. Crestani et al.   NEUROSCIENCE RESEARCH

Sustained antagonism of acute ethanol-induced ataxia following microinfusion of cyclic AMP and cpt-cAMP in the mouse cerebellum

(2010) M. Saeed Dar   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats

(2010) Zeng-You Ye et al.   REGULATORY PEPTIDES

Modulation of cardiorespiratory function mediated by the paraventricular nucleus

(2010) Prabha Kc et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

The ‘neuroadrenergic hypothesis’ in hypertension: current evidence

(2009) Guido Grassi et al.   EXPERIMENTAL PHYSIOLOGY

The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunction

(2008) Alastair V Ferguson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Endogenous Melanocortin System Activity Contributes to the Elevated Arterial Pressure in Spontaneously Hypertensive Rats

(2008) Alexandre A. da Silva et al.   HYPERTENSION

Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage

(2007) D Giuliani et al.   BRITISH JOURNAL OF PHARMACOLOGY