An open-label trial in Friedreich ataxia suggests clinical benefit with high-dose resveratrol, without effect on frataxin levels
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An open-label trial in Friedreich ataxia suggests clinical benefit with high-dose resveratrol, without effect on frataxin levels
Authors
Keywords
Friedreich ataxia, Clinical trial, Resveratrol, Oxidative stress, Mitochondrial disorder
Journal
JOURNAL OF NEUROLOGY
Volume 262, Issue 5, Pages 1344-1353
Publisher
Springer Nature
Online
2015-04-06
DOI
10.1007/s00415-015-7719-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Rating disease progression of Friedreich’s ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database
- (2013) Günther Metz et al. BRAIN
- Effects of low-fat or full-fat fermented and non-fermented dairy foods on selected cardiovascular biomarkers in overweight adults
- (2013) Paul J. Nestel et al. BRITISH JOURNAL OF NUTRITION
- Review of recent data on the metabolism, biological effects, and toxicity of resveratrol in humans
- (2013) Charles-Henry Cottart et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Pharmacological Screening Using an FXN-EGFP Cellular Genomic Reporter Assay for the Therapy of Friedreich Ataxia
- (2013) Lingli Li et al. PLoS One
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
- (2013) B. P. Hubbard et al. SCIENCE
- A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma
- (2012) Rakesh Popat et al. BRITISH JOURNAL OF HAEMATOLOGY
- SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
- (2012) Nathan L. Price et al. Cell Metabolism
- FXN methylation predicts expression and clinical outcome in Friedreich ataxia
- (2011) Marguerite V. Evans-Galea et al. ANNALS OF NEUROLOGY
- Friedreich's ataxia: Past, present and future
- (2011) Daniele Marmolino BRAIN RESEARCH REVIEWS
- Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases--Safety, Pharmacokinetics, and Pharmacodynamics
- (2011) L. M. Howells et al. Cancer Prevention Research
- Early Changes in Left Ventricular Long-Axis Function in Friedreich Ataxia: Relation with the FXN Gene Mutation and Cardiac Structural Change
- (2011) Philip M. Mottram et al. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
- Correlation of frataxin content in blood and skeletal muscle endorses frataxin as a biomarker in Friedreich ataxia
- (2011) Wolfgang Nachbauer et al. MOVEMENT DISORDERS
- Resveratrol Pretreatment Attenuates Cerebral Ischemic Injury by Upregulating Expression of Transcription Factor Nrf2 and HO-1 in Rats
- (2011) Junwei Ren et al. NEUROCHEMICAL RESEARCH
- What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
- (2011) Ole Vang et al. PLoS One
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study
- (2010) H.-H. S. Chow et al. Cancer Prevention Research
- Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis
- (2010) V. A. Brown et al. CANCER RESEARCH
- Steady-State Pharmacokinetics and Tolerability of Trans-Resveratrol 2000 mg Twice Daily with Food, Quercetin and Alcohol (Ethanol) in Healthy Human Subjects
- (2010) Charles la Porte et al. CLINICAL PHARMACOKINETICS
- Reliability, Stability, and Sensitivity to Change and Impairment in Acoustic Measures of Timing and Frequency
- (2010) Adam P. Vogel et al. JOURNAL OF VOICE
- Measuring the rate of progression in Friedreich ataxia: Implications for clinical trial design
- (2010) Lisa S. Friedman et al. MOVEMENT DISORDERS
- PGC-1alpha Down-Regulation Affects the Antioxidant Response in Friedreich's Ataxia
- (2010) Daniele Marmolino et al. PLoS One
- A high throughput electrochemiluminescence assay for the quantification of frataxin protein levels
- (2009) Hannes Steinkellner et al. ANALYTICA CHIMICA ACTA
- Urine 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a specific marker of oxidative stress, using direct, isocratic LC–MS/MS: Method evaluation and application in study of biological variation in healthy adults
- (2009) Kam-fai Lee et al. CLINICA CHIMICA ACTA
- Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARγ pathway as a therapeutic target in Friedreich’s ataxia
- (2009) Giovanni Coppola et al. HUMAN MOLECULAR GENETICS
- Friedreich's ataxia impact scale: A new measure striving to provide the flexibility required by today's studies
- (2009) Stefan J. Cano et al. MOVEMENT DISORDERS
- Speech perception ability in individuals with Friedreich ataxia
- (2008) Gary Rance et al. BRAIN
- PPAR-γ Agonist Azelaoyl PAF Increases Frataxin Protein and mRNA Expression. New Implications for the Friedreich’s Ataxia Therapy
- (2008) Daniele Marmolino et al. CEREBELLUM
- Lateral-flow immunoassay for the frataxin protein in Friedreich’s ataxia patients and carriers
- (2008) John H. Willis et al. MOLECULAR GENETICS AND METABOLISM
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search