Immune Monitoring of Islet and Pancreas Transplant Recipients

Immune responses against islet allografts during tapering of immunosuppression - a pilot study in 5 subjects

(2012) V. A. L. Huurman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Alloantibody and Autoantibody Monitoring Predicts Islet Transplantation Outcome in Human Type 1 Diabetes

(2012) L. Piemonti et al.   DIABETES

Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

(2012) F. B. Barton et al.   DIABETES CARE

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

(2012) Wendy W. J. Unger et al.   PLoS One

State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression

(2011) A. M. James Shapiro   Current Diabetes Reports

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers

(2011) Wendy W. Unger et al.   JOURNAL OF AUTOIMMUNITY

Islet inflammation and CXCL10 in recent-onset type 1 diabetes

(2010) B. O. Roep et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Recurrence of Type 1 Diabetes After Simultaneous Pancreas-Kidney Transplantation, Despite Immunosuppression, Is Associated With Autoantibodies and Pathogenic Autoreactive CD4 T-Cells

(2010) F. Vendrame et al.   DIABETES

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Prediction and Pathogenesis in Type 1 Diabetes

(2010) Anette-G. Ziegler et al.   IMMUNITY

Evidence for Humoral Rejection of a Pancreatic Islet Graft and Rescue with Rituximab and IV Immunoglobulin Therapy

(2009) L. Kessler et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation

(2009) D. L. Roelen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differences in Baseline Lymphocyte Counts and Autoreactivity Are Associated With Differences in Outcome of Islet Cell Transplantation in Type 1 Diabetic Patients

(2009) R. Hilbrands et al.   DIABETES

Graves Hyperthyroidism After Stopping Immunosuppressive Therapy in Type 1 Diabetic Islet Cell Recipients With Pretransplant TPO Autoantibodies

(2009) P. Gillard et al.   DIABETES CARE

Allograft-Specific Cytokine Profiles Associate with Clinical Outcome After Islet Cell Transplantation

(2008) V. A. L. Huurman et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation

(2008) Elsa Laughlin et al.   CLINICAL IMMUNOLOGY

Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreas allograft of a type 1 diabetic recipient

(2008) J. H. Velthuis et al.   DIABETOLOGIA

Cellular Islet Autoimmunity Associates with Clinical Outcome of Islet Cell Transplantation

(2008) Volkert A. L. Huurman et al.   PLoS One