Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo

Granzyme B Promotes Cytotoxic Lymphocyte Transmigration via Basement Membrane Remodeling

(2014) Monica D. Prakash et al.   IMMUNITY

Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS

(2014) E. Zastepa et al.   NEUROLOGY

Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing

(2014) I Hsu et al.   Cell Death & Disease

The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE)

(2013) Curtis A. Benson et al.   BEHAVIOURAL BRAIN RESEARCH

Bridging, switching or drug holidays – how to treat a patient who stops natalizumab?

(2013) Joachim Havla et al.   Therapeutics and Clinical Risk Management

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n

(2012) Michael J. Coronado et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

(2012) C. G. Bien et al.   BRAIN

Disease Modifying Drugs in Multiple Sclerosis: Mechanisms of Action and New Drugs in the Horizon

(2012) Monica Marta et al.   CNS & Neurological Disorders-Drug Targets

Neurodegeneration in multiple sclerosis: novel treatment strategies

(2012) Felix Luessi et al.   Expert Review of Neurotherapeutics

A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis

(2012) Smriti M Agrawal et al.   Journal of Neuroinflammation

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Measurement and clinical effect of grey matter pathology in multiple sclerosis

(2012) Jeroen JG Geurts et al.   LANCET NEUROLOGY

The MAO inhibitor phenelzine improves functional outcomes in mice with experimental autoimmune encephalomyelitis (EAE)

(2011) Travis Musgrave et al.   BRAIN BEHAVIOR AND IMMUNITY

A quarter century of granzymes

(2011) C L Ewen et al.   CELL DEATH AND DIFFERENTIATION

Granule-Derived Granzyme B Mediates the Vulnerability of Human Neurons to T Cell-Induced Neurotoxicity

(2011) Y. Haile et al.   JOURNAL OF IMMUNOLOGY

CD4+ CD25+ CD127dim Foxp3+ T cells are cytotoxic for human neurons

(2011) Yohannes Haile et al.   JOURNAL OF LEUKOCYTE BIOLOGY

EMMPRIN: A Novel Regulator of Leukocyte Transmigration into the CNS in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

(2011) S. M. Agrawal et al.   JOURNAL OF NEUROSCIENCE

Granzymes in cancer and immunity

(2010) S P Cullen et al.   CELL DEATH AND DIFFERENTIATION

Enhanced Antiviral T Cell Function in the Absence of B7-H1 Is Insufficient To Prevent Persistence but Exacerbates Axonal Bystander Damage during Viral Encephalomyelitis

(2010) T. W. Phares et al.   JOURNAL OF IMMUNOLOGY

Collateral Bystander Damage by Myelin-Directed CD8+ T Cells Causes Axonal Loss

(2009) Bettina Sobottka et al.   AMERICAN JOURNAL OF PATHOLOGY

Interferon-γ Prevents Death of Bystander Neurons during CD8 T Cell Responses in the Brain

(2009) Kirsten Richter et al.   AMERICAN JOURNAL OF PATHOLOGY

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Association of α-Synuclein Immunoreactivity With Inflammatory Activity in Multiple Sclerosis Lesions

(2009) Jian-Qiang Lu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma

(2009) Wendy Anne Boivin et al.   LABORATORY INVESTIGATION

Granzyme-b mediated cell death in the spinal cord-injured rat model

(2009) Ganta Vijay Chaitanya et al.   NEUROPATHOLOGY

Granzyme-b is involved in mediating post-ischemic neuronal death during focal cerebral ischemia in rat model

(2009) G.V. Chaitanya et al.   NEUROSCIENCE

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE)

(2008) Camille J. Olechowski et al.   PAIN