The Role of Antisense Oligonucleotide Therapy in Patients with Familial Hypercholesterolemia: Risks, Benefits, and Management Recommendations
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Role of Antisense Oligonucleotide Therapy in Patients with Familial Hypercholesterolemia: Risks, Benefits, and Management Recommendations
Authors
Keywords
Familial hypercholesterolemia, LDL cholesterol, ASO, Antisense oligonucleotide therapy, Mipomersen
Journal
Current Atherosclerosis Reports
Volume 17, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-11-15
DOI
10.1007/s11883-014-0467-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Lomitapide: A novel agent for the treatment of homozygous familial hypercholesterolemia
- (2014) K. A. Davis et al. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
- Antisense Oligonucleotide-Based Therapy in Human Erythropoietic Protoporphyria
- (2014) Vincent Oustric et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Lomitapide and Mipomersen
- (2014) Daniel J. Rader et al. CIRCULATION
- Update on Primary Hypobetalipoproteinemia
- (2014) Amanda J. Hooper et al. Current Atherosclerosis Reports
- Targeting the androgen receptor in prostate cancer
- (2014) Zoran Culig EXPERT OPINION ON PHARMACOTHERAPY
- Modulation of Hepcidin as Therapy for Primary and Secondary Iron Overload Disorders
- (2014) Paul J. Schmidt et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Lack of Clinical Pharmacodynamic and Pharmacokinetic Drug–Drug Interactions Between Warfarin and the Antisense Oligonucleotide Mipomersen
- (2014) Zhaoyang Li et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Lipoprotein(a) and Cardiovascular Disease in Heterozygous Familial Hypercholesterolemia
- (2014) Raul D. Santos JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The Severe Hypercholesterolemia Phenotype
- (2014) Allan D. Sniderman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice
- (2014) Xianjun Gao et al. MOLECULAR THERAPY
- Antisense Oligonucleotides Targeting Parasite Inositol 1,4,5-Trisphosphate Receptor Inhibits Mammalian Host Cell Invasion by Trypanosoma cruzi
- (2014) Muneaki Hashimoto et al. Scientific Reports
- Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy
- (2014) Andrew P. Lieberman et al. Cell Reports
- Changes in Mipomersen Dosing Regimen Provide Similar Exposure With Improved Tolerability in Randomized Placebo‐Controlled Study of Healthy Volunteers
- (2014) JoAnn D. Flaim et al. Journal of the American Heart Association
- Diagnosis and treatment of familial hypercholesterolaemia
- (2013) G. Kees Hovingh et al. EUROPEAN HEART JOURNAL
- Mipomersen, an Apolipoprotein B Synthesis Inhibitor, Reduces Atherogenic Lipoproteins in Patients With Severe Hypercholesterolemia at High Cardiovascular Risk
- (2013) Gregory S. Thomas et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Antisense battles small molecule for slice of rare lipid disorder market
- (2013) Gunjan Sinha NATURE BIOTECHNOLOGY
- Prospects for nucleic acid-based therapeutics against hepatitis C virus
- (2013) Chang Ho Lee WORLD JOURNAL OF GASTROENTEROLOGY
- Apolipoprotein B Synthesis Inhibition With Mipomersen in Heterozygous Familial Hypercholesterolemia
- (2012) Evan A. Stein et al. CIRCULATION
- Randomized, Placebo-Controlled Trial of Mipomersen in Patients with Severe Hypercholesterolemia Receiving Maximally Tolerated Lipid-Lowering Therapy
- (2012) Mary P. McGowan et al. PLoS One
- Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia
- (2011) Fatima Akdim et al. EUROPEAN HEART JOURNAL
- Management of Familial Hypercholesterolemias in adult patients: Recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
- (2011) Matthew K. Ito et al. Journal of Clinical Lipidology
- Familial Hypercholesterolemia: Screening, diagnosis and management of pediatric and adult patients
- (2011) Anne C. Goldberg et al. Journal of Clinical Lipidology
- Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice
- (2011) Adam E. Mullick et al. JOURNAL OF LIPID RESEARCH
- Effect of Mipomersen, an Apolipoprotein B Synthesis Inhibitor, on Low-Density Lipoprotein Cholesterol in Patients With Familial Hypercholesterolemia
- (2010) Fatima Akdim et al. AMERICAN JOURNAL OF CARDIOLOGY
- RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
- (2010) C. Frank Bennett et al. Annual Review of Pharmacology and Toxicology
- Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy
- (2010) Fatima Akdim et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
- (2010) Frederick J Raal et al. LANCET
- Other Therapies for Reducing Low-Density Lipoprotein Cholesterol: Medications in Development
- (2009) Evan A. Stein ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now