Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease

Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

(2014) J. K. Alder et al.   JOURNAL OF IMMUNOLOGY

CD14CD16 Monocyte Subset Levels in Heart Failure Patients

(2013) Chiara Barisione et al.   DISEASE MARKERS

Elevated CD14 ++ CD16 − Monocytes Predict Cardiovascular Events

(2012) Katarina E. Berg et al.   Circulation-Cardiovascular Genetics

Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis

(2012) Florian Leuschner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origins of tumor-associated macrophages and neutrophils

(2012) V. Cortez-Retamozo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

CD14 dim CD16 + and CD14 + CD16 + Monocytes in Obesity and During Weight Loss

(2011) Christine Poitou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Oral Spleen Tyrosine Kinase Inhibitor Fostamatinib Attenuates Inflammation and Atherogenesis in Low-Density Lipoprotein Receptor–Deficient Mice

(2011) Ingo Hilgendorf et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Incidence of Coronary Events and Case Fatality Rate in Relation to Blood Lymphocyte and Neutrophil Counts

(2011) Samuel Adamsson Eryd et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset

(2011) A. M. Zawada et al.   BLOOD

Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets

(2011) K. L. Wong et al.   BLOOD

Extramedullary Hematopoiesis Generates Ly-6C high Monocytes That Infiltrate Atherosclerotic Lesions

(2011) Clinton S. Robbins et al.   CIRCULATION

Identification of a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Adventitia of Postnatal Murine Aorta

(2011) Peter J. Psaltis et al.   CIRCULATION

Binding of CD40L to Mac-1's I-Domain Involves the EQLKKSKTL Motif and Mediates Leukocyte Recruitment and Atherosclerosis—But Does Not Affect Immunity and Thrombosis in Mice

(2011) Dennis Wolf et al.   CIRCULATION RESEARCH

Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity

(2011) Isabelle T.M.N. Daissormont et al.   CIRCULATION RESEARCH

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

(2011) Anouk A.J. Hamers et al.   CIRCULATION RESEARCH

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis

(2011) Jae-Hoon Choi et al.   IMMUNITY

Dendritic Cell and Macrophage Heterogeneity In Vivo

(2011) Daigo Hashimoto et al.   IMMUNITY

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

(2011) Andrew J. Murphy et al.   JOURNAL OF CLINICAL INVESTIGATION

The CD14++CD16+ monocyte subset and monocyte-platelet interactions in patients with ST-elevation myocardial infarction

(2011) L. D. TAPP et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris

(2010) Toshio Imanishi et al.   ATHEROSCLEROSIS

Association of monocyte subsets with vulnerability characteristics of coronary plaques as assessed by 64-slice multidetector computed tomography in patients with stable angina pectoris

(2010) Manabu Kashiwagi et al.   ATHEROSCLEROSIS

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Association Between Circulating Monocyte Subsets and In-Stent Restenosis After Coronary Stent Implantation in Patients With ST-Elevation Myocardial Infarction

(2010) Yong Liu et al.   CIRCULATION JOURNAL

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction

(2010) Florian Leuschner et al.   CIRCULATION RESEARCH

CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease

(2010) Kyrill S. Rogacev et al.   EUROPEAN HEART JOURNAL

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis

(2010) Peter Panizzi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Peripheral Blood CD14high CD16+Monocytes are Main Producers of IL-10

(2010) J. Skrzeczyńska-Moncznik et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Circulating monocyte subsets and cardio - vascular risk factors in coronary artery disease

(2010) Mihail Hristov et al.   THROMBOSIS AND HAEMOSTASIS

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

Leukocyte count in peripheral arterial disease: A simple, reliable, inexpensive approach to cardiovascular risk prediction

(2009) Giuseppe Giugliano et al.   ATHEROSCLEROSIS

Comparison of gene expression profiles between human and mouse monocyte subsets

(2009) M. A. Ingersoll et al.   BLOOD

Functional Role of CD11c + Monocytes in Atherogenesis Associated With Hypercholesterolemia

(2009) Huaizhu Wu et al.   CIRCULATION

Monocyte Subtypes Predict Clinical Course and Prognosis in Human Stroke

(2009) Xabier Urra et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

(2009) Su-Ning Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impact of Heterogeneity of Human Peripheral Blood Monocyte Subsets on Myocardial Salvage in Patients With Primary Acute Myocardial Infarction

(2009) Hiroto Tsujioka et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Monocyte Subset Dynamics in Human Atherosclerosis Can Be Profiled with Magnetic Nano-Sensors

(2009) Moritz Wildgruber et al.   PLoS One

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

P-Selectin Glycoprotein Ligand-1 Is Highly Expressed on Ly-6C hi Monocytes and a Major Determinant for Ly-6C hi Monocyte Recruitment to Sites of Atherosclerosis in Mice

(2008) Guangyu An et al.   CIRCULATION

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

(2008) Christophe Combadière et al.   CIRCULATION

Exercise training-induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise?

(2008) Kyle L. Timmerman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

CD14++CD16+ monocytes but not total monocyte numbers predict cardiovascular events in dialysis patients

(2007) G.H. Heine et al.   KIDNEY INTERNATIONAL

Predictive value of white blood cell subtypes for long-term outcome following myocardial infarction

(2006) Robert Dragu et al.   ATHEROSCLEROSIS