Neurochemical Metabolomics Reveals Disruption to Sphingolipid Metabolism Following Chronic Haloperidol Administration

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis

(2013) Stefan Leucht et al.   LANCET

Biological functions of sphingomyelins

(2013) J. Peter Slotte   PROGRESS IN LIPID RESEARCH

Update on Typical and Atypical Antipsychotic Drugs

(2012) Herbert Y. Meltzer   Annual Review of Medicine

Extrapyramidal motor side-effects of first- and second-generation antipsychotic drugs

(2012) Michael J. Peluso et al.   BRITISH JOURNAL OF PSYCHIATRY

Large-scale neurochemical metabolomics analysis identifies multiple compounds associated with methamphetamine exposure

(2012) Joseph L. McClay et al.   Metabolomics

Metabolomics: the apogee of the omics trilogy

(2012) Gary J. Patti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

(2012) J. Xia et al.   NUCLEIC ACIDS RESEARCH

The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013

(2012) Janna Hastings et al.   NUCLEIC ACIDS RESEARCH

mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia

(2012) Rafal T. Olszewski et al.   SCHIZOPHRENIA RESEARCH

Increased N-acetylaspartate in model mouse of pelizaeus-merzbacher disease

(2011) Jun-ichi Takanashi et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

(2011) James J. Crowley et al.   MAMMALIAN GENOME

Human metabolic individuality in biomedical and pharmaceutical research

(2011) Karsten Suhre et al.   NATURE

Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst

(2011) Jianguo Xia et al.   Nature Protocols

N-Acetylaspartylglutamate (NAAG) and N-Acetylaspartate (NAA) in Patients With Schizophrenia

(2011) Frank Jessen et al.   SCHIZOPHRENIA BULLETIN

C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements

(2010) Smadar Levy et al.   IUBMB LIFE

Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice

(2010) J J Crowley et al.   PHARMACOGENOMICS JOURNAL

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

(2010) Corey D DeHaven et al.   Journal of Cheminformatics

Differential Expression of Metabotropic Glutamate Receptors 2 and 3 in Schizophrenia: A Mechanism for Antipsychotic Drug Action?

(2009) Subroto Ghose et al.   AMERICAN JOURNAL OF PSYCHIATRY

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

Genomewide Association Study of Movement-Related Adverse Antipsychotic Effects

(2009) Karolina Åberg et al.   BIOLOGICAL PSYCHIATRY

The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

(2009) K. Kolodziejczyk et al.   BRAIN

The consolidation of neuroleptic therapy: Janssen, the discovery of haloperidol and its introduction into clinical practice

(2009) Francisco López-Muñoz et al.   BRAIN RESEARCH BULLETIN

Antipsychotic-Induced Extrapyramidal Side Effects in Bipolar Disorder and Schizophrenia

(2009) Keming Gao et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

In situ3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: a new tool for metabolomics research

(2009) Robin A. de Graaf et al.   JOURNAL OF NEUROCHEMISTRY

Analyzing the Effects of Psychotropic Drugs on Metabolite Profiles in Rat Brain Using1H NMR Spectroscopy

(2009) Gerard A. McLoughlin et al.   JOURNAL OF PROTEOME RESEARCH

Schizophrenia

(2009) Jim van Os et al.   LANCET

SMPDB: The Small Molecule Pathway Database

(2009) Alex Frolkis et al.   NUCLEIC ACIDS RESEARCH

Untargeted Metabolomic Profiling as an Evaluative Tool of Fenofibrate-Induced Toxicology in Fischer 344 Male Rats

(2009) Tetsuya Ohta et al.   TOXICOLOGIC PATHOLOGY

Metabonomic studies of schizophrenia and psychotropic medications: focus on alterations in CNS energy homeostasis

(2009) Dan Ma et al.   Bioanalysis

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system

(2008) T OKADA et al.   CELLULAR SIGNALLING

N-Acetylaspartate and N-acetylaspartylglutamate: Neurobiology and clinical significance

(2008) E. E. Benarroch   NEUROLOGY